TYW5 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description tRNA-yW synthesizing protein 5 (NCBI Entrez Gene Database, 129450)
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Genes

312 genes differentially expressed following the TYW5 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
KLF4 Kruppel-like factor 4 (gut) 4.2343
TAS1R1 taste receptor, type 1, member 1 4.2343
LAMP5 lysosomal-associated membrane protein family, member 5 4.2343
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 4.2343
SPDYE11 speedy/RINGO cell cycle regulator family member E11 4.2343
NUTM2A NUT family member 2A 4.2343
FLI1 Fli-1 proto-oncogene, ETS transcription factor 4.2343
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 4.2343
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 4.2343
NAPSA napsin A aspartic peptidase 4.2343
CHADL chondroadherin-like 4.2343
AKAP14 A kinase (PRKA) anchor protein 14 4.2343
OTOP2 otopetrin 2 4.2343
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 4.2343
CSP2 CS pseudogene 2 4.2343
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 4.2343
CPNE8-AS1 CPNE8 antisense RNA 1 4.2343
PITX3 paired-like homeodomain 3 4.2343
MYOT myotilin 4.2343
LOC124903233 uncharacterized LOC124903233 4.2343
CCNA1 cyclin A1 4.2343
IL17B interleukin 17B 4.20929
C1ORF141 chromosome 1 open reading frame 141 4.20929
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 4.20929
UMODL1 uromodulin-like 1 4.20929
RAB7B RAB7B, member RAS oncogene family 4.20929
BSX brain-specific homeobox 4.20929
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 4.20929
UNC45B unc-45 homolog B (C. elegans) 4.20929
TCAF2 TRPM8 channel-associated factor 2 4.20929
FAM3D family with sequence similarity 3, member D 4.20929
SHCBP1L SHC SH2-domain binding protein 1-like 4.20929
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 4.20929
RBP3 retinol binding protein 3, interstitial 4.20929
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 4.20929
TMEM89 transmembrane protein 89 4.20929
ZNF648 zinc finger protein 648 4.20929
ANXA2R annexin A2 receptor 4.20929
EPHB3 EPH receptor B3 4.20929
HAS1 hyaluronan synthase 1 4.20929
IL18R1 interleukin 18 receptor 1 4.20929
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 4.20929
CD34 CD34 molecule 4.20929
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 4.20929
THEMIS thymocyte selection associated 4.20929
FAM181B family with sequence similarity 181, member B 4.20929
ETV7 ets variant 7 4.20929
SETSIP SET-like protein 4.20929
COL15A1 collagen, type XV, alpha 1 4.20929
S100A2 S100 calcium binding protein A2 4.20929
DKK2 dickkopf WNT signaling pathway inhibitor 2 4.20929
KIF2B kinesin family member 2B 4.20929
ADAMTSL5 ADAMTS-like 5 4.20929
TUBB1 tubulin, beta 1 class VI 4.20929
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 4.20929
AWAT2 acyl-CoA wax alcohol acyltransferase 2 4.20929
MYH13 myosin, heavy chain 13, skeletal muscle 4.20929
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 4.20929
LOC124901449 uncharacterized LOC124901449 4.20929
EXOC3L4 exocyst complex component 3-like 4 4.20929
LTA lymphotoxin alpha 4.20929
NDP Norrie disease (pseudoglioma) 4.20929
CSAG3 CSAG family, member 3 4.20929
FAM228A family with sequence similarity 228, member A 4.20929
ZNF705A zinc finger protein 705A 4.20929
ADRB1 adrenoceptor beta 1 4.20929
OTOR otoraplin 4.20929
NSG2 neuronal vesicle trafficking associated 2 4.20929
ATP5MGL ATP synthase membrane subunit g like 4.20929
TERB1 telomere repeat binding bouquet formation protein 1 4.20929
H2BW1 H2B.W histone 1 4.20929
LHFPL7 LHFPL tetraspan subfamily member 7 4.20929
ERVFRD-1 endogenous retrovirus group FRD, member 1 4.20929
CLDN9 claudin 9 4.20929
PRB2 proline-rich protein BstNI subfamily 2 4.20929
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 4.20929
AADACL4 arylacetamide deacetylase-like 4 4.20929
GJB3 gap junction protein, beta 3, 31kDa 4.20929
PNMA5 paraneoplastic Ma antigen family member 5 4.20929
HORMAD1 HORMA domain containing 1 4.20929
TMEM176B transmembrane protein 176B 4.20929
ASB15 ankyrin repeat and SOCS box containing 15 4.20929
COL20A1 collagen, type XX, alpha 1 4.20929
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 4.20929
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 4.20929
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 4.20929
PVRIG poliovirus receptor related immunoglobulin domain containing 4.20929
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit 4.20929
DNAI1 dynein, axonemal, intermediate chain 1 4.20929
PTTG2 pituitary tumor-transforming 2 4.20929
IL12RB1 interleukin 12 receptor, beta 1 4.20929
CCIN calicin 4.20929
C20ORF204 chromosome 20 open reading frame 204 4.20929
VNN2 vanin 2 4.20929
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 4.20929
CLEC7A C-type lectin domain family 7, member A 4.20929
PLA1A phospholipase A1 member A 4.20929
CT55 cancer/testis antigen 55 4.20929
ZMYND12 zinc finger, MYND-type containing 12 4.20929
C20ORF144 chromosome 20 open reading frame 144 4.20929
TEX12 testis expressed 12 4.20929
TCF21 transcription factor 21 4.20929
FIGLA folliculogenesis specific basic helix-loop-helix 4.20929
RAD9B RAD9 homolog B (S. pombe) 4.20929
UTS2R urotensin 2 receptor 4.20929
SEC14L3 SEC14-like 3 (S. cerevisiae) 4.20929
FBXO39 F-box protein 39 4.20929
VWA3B von Willebrand factor A domain containing 3B 4.20929
WFDC6 WAP four-disulfide core domain 6 4.20929
CLDN34 claudin 34 4.20929
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 4.20929
CDH19 cadherin 19, type 2 4.20929
OR56A3 olfactory receptor, family 56, subfamily A, member 3 4.20929
RANBP3L RAN binding protein 3-like 4.20929
EMP1 epithelial membrane protein 1 4.20929
GLYATL3 glycine-N-acyltransferase-like 3 4.20929
KRT3 keratin 3, type II 4.20929
DRD2 dopamine receptor D2 4.20929
LMOD2 leiomodin 2 (cardiac) 4.20929
FZD1 frizzled class receptor 1 4.20929
RP1 retinitis pigmentosa 1 (autosomal dominant) 4.20929
TSPYL6 TSPY-like 6 4.20929
DLX3 distal-less homeobox 3 4.20929
ALLC allantoicase 4.20929
CCNI2 cyclin I family, member 2 4.20929
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 4.20929
LYZL1 lysozyme-like 1 4.20929
GOLGA8R golgin A8 family, member R 4.20929
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 4.20929
IL37 interleukin 37 4.20929
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 4.20929
GSTA1 glutathione S-transferase alpha 1 4.20929
WFDC9 WAP four-disulfide core domain 9 4.20929
LAMP3 lysosomal-associated membrane protein 3 4.20929
EPO erythropoietin 4.20929
PSORS1C1 psoriasis susceptibility 1 candidate 1 4.20929
SLC7A4 solute carrier family 7, member 4 4.20929
FADS6 fatty acid desaturase 6 4.20929
SLITRK1 SLIT and NTRK-like family, member 1 4.20929
ROM1 retinal outer segment membrane protein 1 4.20929
MMP3 matrix metallopeptidase 3 4.20929
TF transferrin 4.20929
NPAS4 neuronal PAS domain protein 4 4.20929
FLG2 filaggrin family member 2 4.20929
LIF leukemia inhibitory factor 4.15852
SDS serine dehydratase 4.15852
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 4.15852
ADPRH ADP-ribosylarginine hydrolase 4.15852
DUSP26 dual specificity phosphatase 26 (putative) 4.15852
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 4.15852
BCL2L10 BCL2-like 10 (apoptosis facilitator) 3.66235
CDIP1 cell death-inducing p53 target 1 3.61736
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 3.25117
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 3.15988
MLIP muscular LMNA-interacting protein 3.10846
LINGO3 leucine rich repeat and Ig domain containing 3 3.10846
RNF17 ring finger protein 17 3.10846
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 3.10846
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 3.10846
DRC1 dynein regulatory complex subunit 1 3.10846
STAR steroidogenic acute regulatory protein 3.10846
TNN tenascin N 3.10846
PRR14 proline rich 14 3.10276
DCAF10 DDB1 and CUL4 associated factor 10 3.09353
MOCS2 molybdenum cofactor synthesis 2 2.97187
RNF31 ring finger protein 31 2.85082
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.84658
DNAH2 dynein, axonemal, heavy chain 2 2.81232
POT1 protection of telomeres 1 2.78158
LAT2 linker for activation of T cells family, member 2 2.7696
WTAP Wilms tumor 1 associated protein 2.76333
OPRK1 opioid receptor, kappa 1 2.47941
SLC7A6OS solute carrier family 7, member 6 opposite strand 2.4794
MRPS12 mitochondrial ribosomal protein S12 2.43916
IL10RB interleukin 10 receptor, beta 2.43599
PCDHB3 protocadherin beta 3 2.42608
CRYBG3 beta-gamma crystallin domain containing 3 2.40892
CZIB CXXC motif containing zinc binding protein 2.38221
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.36277
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 2.3305
ZSWIM3 zinc finger, SWIM-type containing 3 2.3305
MAGED4 melanoma antigen family D4 2.31694
LBHD1 LBH domain containing 1 2.31694
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.31694
DUSP22 dual specificity phosphatase 22 2.30411
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.30316
ZBTB7A zinc finger and BTB domain containing 7A 2.26525
SNX12 sorting nexin 12 2.26525
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 2.26525
ZFP69B ZFP69 zinc finger protein B 2.26525
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.23859
TREH trehalase (brush-border membrane glycoprotein) 2.23859
C2ORF69 chromosome 2 open reading frame 69 2.23755
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.23358
HOMEZ homeobox and leucine zipper encoding 2.21549
GOT1 glutamic-oxaloacetic transaminase 1, soluble 2.21435
MCM10 minichromosome maintenance complex component 10 2.20612
MXRA7 matrix-remodelling associated 7 2.18359
GCLM glutamate-cysteine ligase, modifier subunit 2.15792
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.13884
CCDC85A coiled-coil domain containing 85A 2.12758
CTTNBP2NL CTTNBP2 N-terminal like 2.12758
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) 2.1236
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.10141
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.08375
EAPP E2F-associated phosphoprotein 2.07087
CEP120 centrosomal protein 120kDa 2.06334
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.04631
IFRD1 interferon-related developmental regulator 1 2.02466
CYTL1 cytokine-like 1 2.02415
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 2.01262
GPATCH2L G patch domain containing 2-like 2.00253

decreased expression

Symbol Name Standardized Value
ZDHHC11B zinc finger, DHHC-type containing 11B -4.2343
EPOP elongin BC and polycomb repressive complex 2 associated protein -4.2343
SPMIP4 sperm microtubule inner protein 4 -4.2343
IKZF3 IKAROS family zinc finger 3 (Aiolos) -4.2343
PLSCR2 phospholipid scramblase 2 -4.2343
TM4SF1 transmembrane 4 L six family member 1 -4.20929
RRAD Ras-related associated with diabetes -4.20929
TMEM100 transmembrane protein 100 -4.20929
LGALS9 lectin, galactoside-binding, soluble, 9 -4.20929
TSHZ1 teashirt zinc finger homeobox 1 -4.20929
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) -4.20929
PCDHGA11 protocadherin gamma subfamily A, 11 -4.20929
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like -4.20929
ZC3H11C zinc finger CCCH-type containing 11C -4.20929
NXPH4 neurexophilin 4 -4.20929
SLC26A9 solute carrier family 26 (anion exchanger), member 9 -4.20929
CFAP157 cilia and flagella associated protein 157 -4.20929
DEPP1 DEPP autophagy regulator 1 -4.20929
CFAP65 cilia and flagella associated protein 65 -4.20929
SPRR2F small proline-rich protein 2F -4.20929
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -4.20929
OR2A14 olfactory receptor, family 2, subfamily A, member 14 -4.20929
SYT15 synaptotagmin XV -4.20929
MIA melanoma inhibitory activity -4.20929
CATSPERD catsper channel auxiliary subunit delta -4.20929
SPDYE6 speedy/RINGO cell cycle regulator family member E6 -4.20929
TRPM5 transient receptor potential cation channel, subfamily M, member 5 -4.20929
AMER2 APC membrane recruitment protein 2 -4.20929
ART1 ADP-ribosyltransferase 1 -4.20929
NIM1K NIM1 serine/threonine protein kinase -4.20929
IER5L immediate early response 5-like -4.20929
CLRN1 clarin 1 -4.20929
PTGDR prostaglandin D2 receptor (DP) -4.20929
WFDC8 WAP four-disulfide core domain 8 -4.20929
TSPAN16 tetraspanin 16 -4.20929
THRA thyroid hormone receptor, alpha -4.15965
ADRA1A adrenoceptor alpha 1A -4.15852
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 -4.15852
TMEM221 transmembrane protein 221 -4.15852
SHROOM1 shroom family member 1 -3.66027
ATP5MC3 ATP synthase membrane subunit c locus 3 -3.4482
ZP3 zona pellucida glycoprotein 3 (sperm receptor) -3.26946
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -3.14496
DRC3 dynein regulatory complex subunit 3 -3.10133
FIG4 FIG4 phosphoinositide 5-phosphatase -3.07784
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -2.96862
MAP7 microtubule-associated protein 7 -2.96862
TLR2 toll-like receptor 2 -2.89828
TESK1 testis-specific kinase 1 -2.88623
FYTTD1 forty-two-three domain containing 1 -2.77172
NEURL1B neuralized E3 ubiquitin protein ligase 1B -2.74208
RPH3AL rabphilin 3A-like (without C2 domains) -2.59463
SIRT4 sirtuin 4 -2.52416
OLFML2A olfactomedin-like 2A -2.49258
ZNF587 zinc finger protein 587 -2.48351
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -2.47576
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.4715
FAM186B family with sequence similarity 186, member B -2.46653
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B -2.46653
ATG4D autophagy related 4D, cysteine peptidase -2.46653
EPHA7 EPH receptor A7 -2.4564
GOLGA8A golgin A8 family, member A -2.43916
ZNF487 zinc finger protein 487 -2.42608
RNF180 ring finger protein 180 -2.39135
TP53BP1 tumor protein p53 binding protein 1 -2.37771
FUNDC1 FUN14 domain containing 1 -2.35274
TCF4 transcription factor 4 -2.34483
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.33261
PCDHA4 protocadherin alpha 4 -2.33261
ZMYM1 zinc finger, MYM-type 1 -2.3305
JMJD1C jumonji domain containing 1C -2.31336
YAF2 YY1 associated factor 2 -2.30411
GSTO2 glutathione S-transferase omega 2 -2.29472
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -2.28574
OLFM3 olfactomedin 3 -2.27499
ANO1 anoctamin 1, calcium activated chloride channel -2.27164
NCF2 neutrophil cytosolic factor 2 -2.26525
FRZB frizzled-related protein -2.26525
GYPE glycophorin E (MNS blood group) -2.26525
C19ORF38 chromosome 19 open reading frame 38 -2.26525
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.26525
TTC29 tetratricopeptide repeat domain 29 -2.26525
TCP11L2 t-complex 11, testis-specific-like 2 -2.24675
RUNX2 runt-related transcription factor 2 -2.23157
SAR1B secretion associated, Ras related GTPase 1B -2.21435
PQBP1 polyglutamine binding protein 1 -2.21074
INAFM1 InaF-motif containing 1 -2.18483
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -2.16521
ATP11A ATPase, class VI, type 11A -2.15792
SNTG2 syntrophin, gamma 2 -2.13049
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.1101
TMEM38B transmembrane protein 38B -2.10718
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -2.09731
CHPT1 choline phosphotransferase 1 -2.08768
AFF2 AF4/FMR2 family, member 2 -2.08768
VEZT vezatin, adherens junctions transmembrane protein -2.08353
APOL2 apolipoprotein L, 2 -2.077
STRADB STE20-related kinase adaptor beta -2.04312
FOXP1 forkhead box P1 -2.0162
ATAT1 alpha tubulin acetyltransferase 1 -2.01057