Tachycardia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A rapid heartrate that exceeds the range of the normal resting heartrate for age. (Human Phenotype Ontology, HP_0001649)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D013610
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Genes

727 genes/proteins associated with the disease Tachycardia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 2.88009
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 2.88009
VIP vasoactive intestinal peptide 2.88009
TRH thyrotropin-releasing hormone 2.88009
INS insulin 2.88009
LHB luteinizing hormone beta polypeptide 2.88009
LEP leptin 2.88009
TNF tumor necrosis factor 2.88009
BCHE butyrylcholinesterase 2.88009
DRD2 dopamine receptor D2 2.88009
GAL galanin/GMAP prepropeptide 2.88009
AHR aryl hydrocarbon receptor 2.88009
SCT secretin 2.88009
VAV3 vav 3 guanine nucleotide exchange factor 2.88009
GNAS GNAS complex locus 2.88009
RYR2 ryanodine receptor 2 (cardiac) 2.88009
GCG glucagon 2.88009
REN renin 2.5613
MAPK1 mitogen-activated protein kinase 1 2.54957
MAPK3 mitogen-activated protein kinase 3 2.5494
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.54862
ADRB1 adrenoceptor beta 1 2.54823
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.54797
FOS FBJ murine osteosarcoma viral oncogene homolog 2.54672
CAT catalase 2.53085
BCL2 B-cell CLL/lymphoma 2 2.52875
ADRB2 adrenoceptor beta 2, surface 2.52246
IL6 interleukin 6 2.51972
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.5178
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.51458
BAX BCL2-associated X protein 2.50743
NPPA natriuretic peptide A 2.49673
IL1B interleukin 1, beta 2.49361
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.49264
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.49204
PRL prolactin 2.48696
NOS2 nitric oxide synthase 2, inducible 2.4545
BDNF brain-derived neurotrophic factor 2.45142
EDN1 endothelin 1 2.44737
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.44524
TGFB1 transforming growth factor, beta 1 2.43864
TH tyrosine hydroxylase 2.43389
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.42908
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.42428
CCL2 chemokine (C-C motif) ligand 2 2.41927
CRH corticotropin releasing hormone 2.41129
JUN jun proto-oncogene 2.4106
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.40506
CREB1 cAMP responsive element binding protein 1 2.40233
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.39986
NOS3 nitric oxide synthase 3 (endothelial cell) 2.39751
IL10 interleukin 10 2.3968
NPY neuropeptide Y 2.38645
VEGFA vascular endothelial growth factor A 2.37363
AVP arginine vasopressin 2.37163
POMC proopiomelanocortin 2.36761
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.36738
SOD2 superoxide dismutase 2, mitochondrial 2.36584
NPPB natriuretic peptide B 2.34026
EGR1 early growth response 1 2.33791
TP53 tumor protein p53 2.32529
MMP9 matrix metallopeptidase 9 2.32434
MMP2 matrix metallopeptidase 2 2.31862
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.30971
PENK proenkephalin 2.30687
CALCA calcitonin-related polypeptide alpha 2.30516
MPO myeloperoxidase 2.30249
TAC1 tachykinin, precursor 1 2.29947
HMOX1 heme oxygenase 1 2.29157
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.28092
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.28043
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 2.27766
CXCL8 chemokine (C-X-C motif) ligand 8 2.27526
ICAM1 intercellular adhesion molecule 1 2.27499
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.27464
DRD1 dopamine receptor D1 2.27245
ADRB3 adrenoceptor beta 3 2.23543
IGF1 insulin-like growth factor 1 (somatomedin C) 2.23355
GSK3B glycogen synthase kinase 3 beta 2.22957
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.22423
GFAP glial fibrillary acidic protein 2.22096
MAPK8 mitogen-activated protein kinase 8 2.21455
NOS1 nitric oxide synthase 1 (neuronal) 2.21294
MYH7 myosin, heavy chain 7, cardiac muscle, beta 2.20399
BCL2L1 BCL2-like 1 2.20256
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.1838
IL4 interleukin 4 2.18037
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.17737
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.17706
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.17654
IL1A interleukin 1, alpha 2.17138
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.16549
IFNG interferon, gamma 2.16298
PPARG peroxisome proliferator-activated receptor gamma 2.15699
FASLG Fas ligand (TNF superfamily, member 6) 2.15618
COL1A1 collagen, type I, alpha 1 2.15286
NGF nerve growth factor (beta polypeptide) 2.15055
SOD1 superoxide dismutase 1, soluble 2.14621
FAS Fas cell surface death receptor 2.14591
GSTP1 glutathione S-transferase pi 1 2.13697
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.13305
EGFR epidermal growth factor receptor 2.12333
FGF2 fibroblast growth factor 2 (basic) 2.12286
VCAM1 vascular cell adhesion molecule 1 2.11865
OPRM1 opioid receptor, mu 1 2.10341
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 2.09857
MAPK14 mitogen-activated protein kinase 14 2.07854
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.06722
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.06173
APP amyloid beta (A4) precursor protein 2.06076
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.05595
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.05231
DDIT3 DNA-damage-inducible transcript 3 2.04371
CCND1 cyclin D1 2.04045
PPARA peroxisome proliferator-activated receptor alpha 2.04045
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.03185
JUNB jun B proto-oncogene 2.02307
ARC activity-regulated cytoskeleton-associated protein 2.02265
OXT oxytocin/neurophysin I prepropeptide 2.01952
MAOA monoamine oxidase A 2.01105
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.01037
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.0055
GH1 growth hormone 1 1.98989
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.98974
HOMER1 homer scaffolding protein 1 1.98568
ALB albumin 1.98338
PARP1 poly (ADP-ribose) polymerase 1 1.95797
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.95782
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.93875
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.93844
NFE2L2 nuclear factor, erythroid 2-like 2 1.93736
ADIPOQ adiponectin, C1Q and collagen domain containing 1.9369
TIMP1 TIMP metallopeptidase inhibitor 1 1.93674
DUSP1 dual specificity phosphatase 1 1.93322
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.9288
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.92753
GAP43 growth associated protein 43 1.92548
G6PD glucose-6-phosphate dehydrogenase 1.92312
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.92026
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.92009
FN1 fibronectin 1 1.91167
CNR1 cannabinoid receptor 1 (brain) 1.90175
NUPR1 nuclear protein, transcriptional regulator, 1 1.8991
MAP2K1 mitogen-activated protein kinase kinase 1 1.8928
ACHE acetylcholinesterase (Yt blood group) 1.89058
IL12A interleukin 12A 1.88932
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.88786
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.88458
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.87194
LPL lipoprotein lipase 1.86924
IL12B interleukin 12B 1.8655
ACE angiotensin I converting enzyme 1.86271
PRKCE protein kinase C, epsilon 1.85712
PRKCB protein kinase C, beta 1.85415
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.84605
PRKCD protein kinase C, delta 1.84341
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.83948
ODC1 ornithine decarboxylase 1 1.83449
ADRA2A adrenoceptor alpha 2A 1.8306
CREM cAMP responsive element modulator 1.82743
IL2 interleukin 2 1.82673
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.82272
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.82272
FASN fatty acid synthase 1.81939
TLR4 toll-like receptor 4 1.8152
CXCL10 chemokine (C-X-C motif) ligand 10 1.80775
CLU clusterin 1.8068
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.80661
COL3A1 collagen, type III, alpha 1 1.80623
SREBF1 sterol regulatory element binding transcription factor 1 1.79427
MAPK9 mitogen-activated protein kinase 9 1.79044
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.7893
GAST gastrin 1.7872
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.78302
STAR steroidogenic acute regulatory protein 1.77801
CYBB cytochrome b-245, beta polypeptide 1.77801
OPRK1 opioid receptor, kappa 1 1.77179
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.77101
GSTM1 glutathione S-transferase mu 1 1.76849
CYCS cytochrome c, somatic 1.76713
ADORA1 adenosine A1 receptor 1.76597
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.76559
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.76462
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.76462
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.76443
ADRA1D adrenoceptor alpha 1D 1.76405
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.76072
ADORA2A adenosine A2a receptor 1.76072
S100A9 S100 calcium binding protein A9 1.75934
PCNA proliferating cell nuclear antigen 1.7568
GJA1 gap junction protein, alpha 1, 43kDa 1.75381
OPRD1 opioid receptor, delta 1 1.74601
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.74601
LDLR low density lipoprotein receptor 1.74561
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.74281
MSMO1 methylsterol monooxygenase 1 1.7426
TFRC transferrin receptor 1.74099
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.73738
PDYN prodynorphin 1.73231
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.73089
RB1 retinoblastoma 1 1.72863
MAOB monoamine oxidase B 1.72758
CCL5 chemokine (C-C motif) ligand 5 1.72137
CRYAB crystallin, alpha B 1.72096
MMP1 matrix metallopeptidase 1 1.71586
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.71193
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.70844
PLAT plasminogen activator, tissue 1.70491
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.7043
BAD BCL2-associated agonist of cell death 1.70265
APOE apolipoprotein E 1.69825
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.69742
CPT1A carnitine palmitoyltransferase 1A (liver) 1.69405
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.68846
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.68782
ADRA1A adrenoceptor alpha 1A 1.68697
TIMP2 TIMP metallopeptidase inhibitor 2 1.68106
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.68106
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.67675
CTSD cathepsin D 1.6759
IL1RN interleukin 1 receptor antagonist 1.67419
TGFB2 transforming growth factor, beta 2 1.67137
GPX1 glutathione peroxidase 1 1.66964
BAK1 BCL2-antagonist/killer 1 1.66857
AGTR1 angiotensin II receptor, type 1 1.66598
RGS2 regulator of G-protein signaling 2 1.66511
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.66382
NCF1 neutrophil cytosolic factor 1 1.65731
SGK1 serum/glucocorticoid regulated kinase 1 1.65445
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.65358
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.64797
CDK4 cyclin-dependent kinase 4 1.6473
CYBA cytochrome b-245, alpha polypeptide 1.6464
TAGLN transgelin 1.64618
KNG1 kininogen 1 1.64326
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.64326
HSPA1A heat shock 70kDa protein 1A 1.64326
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.64235
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.63966
GSR glutathione reductase 1.63899
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 1.63698
FABP1 fatty acid binding protein 1, liver 1.63406
CXCL2 chemokine (C-X-C motif) ligand 2 1.63272
STAT1 signal transducer and activator of transcription 1, 91kDa 1.63116
SPP1 secreted phosphoprotein 1 1.62915
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.62445
ACTA2 actin, alpha 2, smooth muscle, aorta 1.62312
BIRC5 baculoviral IAP repeat containing 5 1.61736
KLF4 Kruppel-like factor 4 (gut) 1.61413
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.61365
PRKCA protein kinase C, alpha 1.61154
PLCG1 phospholipase C, gamma 1 1.60804
DRD3 dopamine receptor D3 1.60641
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.60501
AGTR2 angiotensin II receptor, type 2 1.60501
FSHB follicle stimulating hormone, beta polypeptide 1.59966
ADCY5 adenylate cyclase 5 1.59567
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.59544
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.59544
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.59497
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.59218
INHBE inhibin, beta E 1.59077
HSPA8 heat shock 70kDa protein 8 1.5903
CTGF connective tissue growth factor 1.58795
S100B S100 calcium binding protein B 1.58232
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.58113
EPO erythropoietin 1.57947
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.57877
F3 coagulation factor III (thromboplastin, tissue factor) 1.57853
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.57712
THBS1 thrombospondin 1 1.57641
PER1 period circadian clock 1 1.57522
POR P450 (cytochrome) oxidoreductase 1.57114
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.5673
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.56582
HPCA hippocalcin 1.56361
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.56312
COMT catechol-O-methyltransferase 1.555
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.55255
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.54888
EGR2 early growth response 2 1.54864
IRS1 insulin receptor substrate 1 1.54815
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.54718
CCL3 chemokine (C-C motif) ligand 3 1.54645
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.54378
CCND3 cyclin D3 1.54232
GADD45A growth arrest and DNA-damage-inducible, alpha 1.54111
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.53772
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.53531
CES2 carboxylesterase 2 1.53531
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.53308
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.53283
EDNRB endothelin receptor type B 1.53061
PF4 platelet factor 4 1.52212
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.52212
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.52212
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.51911
HRH1 histamine receptor H1 1.51886
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.51886
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.51708
GDNF glial cell derived neurotrophic factor 1.51557
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.51557
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.51531
TDO2 tryptophan 2,3-dioxygenase 1.5143
CD36 CD36 molecule (thrombospondin receptor) 1.5123
HSPB1 heat shock 27kDa protein 1 1.5108
S100A8 S100 calcium binding protein A8 1.50903
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.50877
APOA1 apolipoprotein A-I 1.50776
CHRM1 cholinergic receptor, muscarinic 1 1.50423
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.50423
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.50323
FNDC4 fibronectin type III domain containing 4 1.50095
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.49864
CTSB cathepsin B 1.4933
VIM vimentin 1.49174
CHRM5 cholinergic receptor, muscarinic 5 1.49148
HSPA4 heat shock 70kDa protein 4 1.49019
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.48967
BID BH3 interacting domain death agonist 1.48813
ATF4 activating transcription factor 4 1.48787
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.48684
C10ORF10 chromosome 10 open reading frame 10 1.48428
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.48299
MCL1 myeloid cell leukemia 1 1.48068
CALB1 calbindin 1, 28kDa 1.47838
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.47838
ADRA1B adrenoceptor alpha 1B 1.47787
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.4753
RGS4 regulator of G-protein signaling 4 1.4727
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.46858
MMP3 matrix metallopeptidase 3 1.46621
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.46595
ELK1 ELK1, member of ETS oncogene family 1.4633
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.46304
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.45405
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.45352
GPX3 glutathione peroxidase 3 1.45352
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.45063
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 1.45063
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.44845
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.44681
IL2RA interleukin 2 receptor, alpha 1.44626
CCK cholecystokinin 1.44029
THY1 Thy-1 cell surface antigen 1.43946
SELE selectin E 1.43864
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.43591
F2 coagulation factor II (thrombin) 1.43455
FOSL2 FOS-like antigen 2 1.43157
PKM pyruvate kinase, muscle 1.42831
CHRM4 cholinergic receptor, muscarinic 4 1.42804
CXCR4 chemokine (C-X-C motif) receptor 4 1.42723
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.42347
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.42183
APAF1 apoptotic peptidase activating factor 1 1.42183
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.42183
XDH xanthine dehydrogenase 1.41992
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.41667
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.41559
PHGDH phosphoglycerate dehydrogenase 1.41424
MBP myelin basic protein 1.41257
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.40568
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.40568
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.40486
CASP12 caspase 12 (gene/pseudogene) 1.40176
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.40148
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.3998
CTSL cathepsin L 1.39813
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 1.3973
CDK2 cyclin-dependent kinase 2 1.38835
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.38527
CRP C-reactive protein, pentraxin-related 1.38469
LOX lysyl oxidase 1.38071
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.37958
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.3793
COL1A2 collagen, type I, alpha 2 1.37761
HSF1 heat shock transcription factor 1 1.37705
EDNRA endothelin receptor type A 1.3736
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.37246
JUND jun D proto-oncogene 1.37018
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.36648
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.36332
IL18 interleukin 18 1.36104
IL5 interleukin 5 1.36104
MAP2 microtubule-associated protein 2 1.36047
PRKCZ protein kinase C, zeta 1.36047
FOXO1 forkhead box O1 1.35763
ALDOA aldolase A, fructose-bisphosphate 1.35357
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.35184
NTF3 neurotrophin 3 1.35155
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.35155
NQO1 NAD(P)H dehydrogenase, quinone 1 1.35098
MMP13 matrix metallopeptidase 13 1.34897
GLUL glutamate-ammonia ligase 1.34694
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.34694
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.34694
NOX4 NADPH oxidase 4 1.34606
CCND2 cyclin D2 1.34343
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.34256
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.3414
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.34082
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.34053
E2F1 E2F transcription factor 1 1.34053
MT2A metallothionein 2A 1.3388
CCNA2 cyclin A2 1.33612
ESR1 estrogen receptor 1 1.33494
LCN2 lipocalin 2 1.33494
EPHX2 epoxide hydrolase 2, cytoplasmic 1.33405
SIRT1 sirtuin 1 1.33375
GHRL ghrelin/obestatin prepropeptide 1.33022
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.32786
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.32637
GCLM glutamate-cysteine ligase, modifier subunit 1.32369
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.32369
DUSP6 dual specificity phosphatase 6 1.32132
ACACA acetyl-CoA carboxylase alpha 1.32132
C3 complement component 3 1.32103
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.32015
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.31656
MAP2K2 mitogen-activated protein kinase kinase 2 1.31506
ATF3 activating transcription factor 3 1.30788
RAMP3 receptor (G protein-coupled) activity modifying protein 3 1.30574
CKM creatine kinase, muscle 1.30482
CHGA chromogranin A 1.30177
SYN2 synapsin II 1.30177
FOSL1 FOS-like antigen 1 1.30177
ANXA1 annexin A1 1.29966
ACO2 aconitase 2, mitochondrial 1.29966
DRD4 dopamine receptor D4 1.29812
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.29626
TPI1 triosephosphate isomerase 1 1.29564
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.29533
LBP lipopolysaccharide binding protein 1.29471
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 1.29379
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.29164
ARRB2 arrestin, beta 2 1.2861
TGFB3 transforming growth factor, beta 3 1.28333
PLAU plasminogen activator, urokinase 1.28027
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.28027
SST somatostatin 1.28027
S100A4 S100 calcium binding protein A4 1.27533
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 1.27533
CKB creatine kinase, brain 1.27162
PDE4B phosphodiesterase 4B, cAMP-specific 1.27162
NEFH neurofilament, heavy polypeptide 1.27162
MYL9 myosin, light chain 9, regulatory 1.2707
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.26856
CALR calreticulin 1.26794
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.26763
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.26607
FGF1 fibroblast growth factor 1 (acidic) 1.26452
BDKRB1 bradykinin receptor B1 1.26298
NTS neurotensin 1.26175
PECAM1 platelet/endothelial cell adhesion molecule 1 1.25713
CYP3A cytochrome P450, family 3, subfamily A 1.25713
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.25494
BDKRB2 bradykinin receptor B2 1.25276
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.25245
IL23A interleukin 23, alpha subunit p19 1.25214
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 1.25059
DUSP8 dual specificity phosphatase 8 1.25059
BIRC3 baculoviral IAP repeat containing 3 1.24997
NAMPT nicotinamide phosphoribosyltransferase 1.24874
CAPN2 calpain 2, (m/II) large subunit 1.24843
MAPT microtubule-associated protein tau 1.24718
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.24655
RHOA ras homolog family member A 1.24528
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.24496
GSK3A glycogen synthase kinase 3 alpha 1.2437
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 1.2437
ADM adrenomedullin 1.24213
THRA thyroid hormone receptor, alpha 1.2415
NCAM1 neural cell adhesion molecule 1 1.24118
HPN hepsin 1.23712
CAV1 caveolin 1, caveolae protein, 22kDa 1.23616
CD14 CD14 molecule 1.23328
APOB apolipoprotein B 1.23265
LDHB lactate dehydrogenase B 1.23074
INHBA inhibin, beta A 1.23042
ADRBK1 adrenergic, beta, receptor kinase 1 1.23011
IGF1R insulin-like growth factor 1 receptor 1.2279
PRLR prolactin receptor 1.22696
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.22664
FLT1 fms-related tyrosine kinase 1 1.22339
PER2 period circadian clock 2 1.22242
VASP vasodilator-stimulated phosphoprotein 1.22048
CFLAR CASP8 and FADD-like apoptosis regulator 1.22016
CDC42 cell division cycle 42 1.21823
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.21759
COX1 1.21402
IGF2 insulin-like growth factor 2 1.21402
NRN1 neuritin 1 1.21337
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.21173
COX5A cytochrome c oxidase subunit Va 1.21108
VCAN versican 1.21011
JAK1 Janus kinase 1 1.20978
SQLE squalene epoxidase 1.20558
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.20526
PVALB parvalbumin 1.20493
ADORA3 adenosine A3 receptor 1.20493
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.20196
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.2013
SYP synaptophysin 1.20031
GCLC glutamate-cysteine ligase, catalytic subunit 1.19966
INSIG1 insulin induced gene 1 1.199
TJP1 tight junction protein 1 1.19868
MB myoglobin 1.19868
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.19704
HINT1 histidine triad nucleotide binding protein 1 1.19704
PLP1 proteolipid protein 1 1.19704
TAAR1 trace amine associated receptor 1 1.19639
ACTA1 actin, alpha 1, skeletal muscle 1.19542
NT5E 5'-nucleotidase, ecto (CD73) 1.19542
CDK1 cyclin-dependent kinase 1 1.19379
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.19345
DHCR24 24-dehydrocholesterol reductase 1.19345
HRH2 histamine receptor H2 1.19279
GRM1 glutamate receptor, metabotropic 1 1.19279
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.19047
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.19014
PDE4A phosphodiesterase 4A, cAMP-specific 1.18948
CHRM3 cholinergic receptor, muscarinic 3 1.18948
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.18652
EFNB3 ephrin-B3 1.18554
PLCD4 phospholipase C, delta 4 1.18554
HBEGF heparin-binding EGF-like growth factor 1.18159
GATA4 GATA binding protein 4 1.18093
SELL selectin L 1.18093
CHAT choline O-acetyltransferase 1.18093
NQO2 NAD(P)H dehydrogenase, quinone 2 1.18093
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.18093
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.17563
CCNB1 cyclin B1 1.173
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.17168
LITAF lipopolysaccharide-induced TNF factor 1.17168
VWF von Willebrand factor 1.17168
HDC histidine decarboxylase 1.17168
KDR kinase insert domain receptor 1.17034
XBP1 X-box binding protein 1 1.17
BECN1 beclin 1, autophagy related 1.17
ENO1 enolase 1, (alpha) 1.17
SDC4 syndecan 4 1.167
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.16666
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.16666
TRIB3 tribbles pseudokinase 3 1.16434
ACTG2 actin, gamma 2, smooth muscle, enteric 1.16368
NOX1 NADPH oxidase 1 1.16368
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.16269
ATF2 activating transcription factor 2 1.16236
STMN1 stathmin 1 1.16203
KRAS Kirsten rat sarcoma viral oncogene homolog 1.1617
IGFBP1 insulin-like growth factor binding protein 1 1.1617
CYC1 cytochrome c-1 1.15967
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.15899
CHRM2 cholinergic receptor, muscarinic 2 1.15865
SMAD3 SMAD family member 3 1.1556
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.15492
EIF4B eukaryotic translation initiation factor 4B 1.15256
ADCY7 adenylate cyclase 7 1.15256
GLRA1 glycine receptor, alpha 1 1.15256
PTK2 protein tyrosine kinase 2 1.15256
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.15223
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.15089
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.15055
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.14919
GSTT1 glutathione S-transferase theta 1 1.1485
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.14541
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.14541
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.1437
CD44 CD44 molecule (Indian blood group) 1.14234
OPRL1 opiate receptor-like 1 1.13862
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.13724
FABP4 fatty acid binding protein 4, adipocyte 1.13689
FGF5 fibroblast growth factor 5 1.13655
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.13621
GPNMB glycoprotein (transmembrane) nmb 1.13586
GSTA1 glutathione S-transferase alpha 1 1.13518
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.13381
E2F3 E2F transcription factor 3 1.13177
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.13143
TNNI3 troponin I type 3 (cardiac) 1.13075
TXN thioredoxin 1.13075
HMGB1 high mobility group box 1 1.1294
BGLAP bone gamma-carboxyglutamate (gla) protein 1.1294
ERP29 endoplasmic reticulum protein 29 1.12564
PARK7 parkinson protein 7 1.12564
SCN5A sodium channel, voltage gated, type V alpha subunit 1.1253
ERBB4 erb-b2 receptor tyrosine kinase 4 1.1253
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.1253
SIGMAR1 sigma non-opioid intracellular receptor 1 1.12323
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.12219
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.12219
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.12219
S100A11 S100 calcium binding protein A11 1.12048
PKLR pyruvate kinase, liver and RBC 1.11911
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.11911
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.11911
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 1.11877
SCG2 secretogranin II 1.11877
OTC ornithine carbamoyltransferase 1.11877
GRIK2 glutamate receptor, ionotropic, kainate 2 1.11877
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.11877
CCNE1 cyclin E1 1.11843
TOP2A topoisomerase (DNA) II alpha 170kDa 1.11775
H2AFX H2A histone family, member X 1.11775
GDF15 growth differentiation factor 15 1.11775
CP ceruloplasmin (ferroxidase) 1.11571
ERN1 endoplasmic reticulum to nucleus signaling 1 1.11501
NCF2 neutrophil cytosolic factor 2 1.11501
USF1 upstream transcription factor 1 1.1129
CDK5 cyclin-dependent kinase 5 1.1122
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.1122
FOXO3 forkhead box O3 1.11186
BAG3 BCL2-associated athanogene 3 1.11081
BPTF bromodomain PHD finger transcription factor 1.11011
IL13 interleukin 13 1.10803
EGF epidermal growth factor 1.10631
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.10596
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 1.10596
PRDX2 peroxiredoxin 2 1.10493
EGR3 early growth response 3 1.10069
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.10069
TEX261 testis expressed 261 1.10069
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.09857
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.09822
PDGFA platelet-derived growth factor alpha polypeptide 1.09822
SOCS3 suppressor of cytokine signaling 3 1.09506
FADD Fas (TNFRSF6)-associated via death domain 1.09471
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 1.09471
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 1.09366
PHB prohibitin 1.09083
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.09083
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.09083
MT1A metallothionein 1A 1.09047
LIN7C lin-7 homolog C (C. elegans) 1.08904
RPS6 ribosomal protein S6 1.08833
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.08726
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.08726
CXCL5 chemokine (C-X-C motif) ligand 5 1.0869
CD40LG CD40 ligand 1.08584
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.08584
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.08549
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.08478
NREP neuronal regeneration related protein 1.08126
CES1 carboxylesterase 1 1.08091
PDGFB platelet-derived growth factor beta polypeptide 1.0784
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.07804
MAPK7 mitogen-activated protein kinase 7 1.07768
ADCY6 adenylate cyclase 6 1.07768
COL18A1 collagen, type XVIII, alpha 1 1.07199
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.07199
CTSK cathepsin K 1.07199
SMAD2 SMAD family member 2 1.07128
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.06987
TUBA4A tubulin, alpha 4a 1.06952
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.06952
BHLHE40 basic helix-loop-helix family, member e40 1.06771
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.06734
GSTM3 glutathione S-transferase mu 3 (brain) 1.06698
SP1 Sp1 transcription factor 1.06698
MAP1B microtubule-associated protein 1B 1.0637
G0S2 G0/G1 switch 2 1.0637
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.06261
CST3 cystatin C 1.06261
UBC ubiquitin C 1.06261
TKT transketolase 1.06261
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.06225
ACTB actin, beta 1.06152
GSTA3 glutathione S-transferase alpha 3 1.06116
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.05828
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.05828
EFNA1 ephrin-A1 1.05828
CCKBR cholecystokinin B receptor 1.05793
ADCY8 adenylate cyclase 8 (brain) 1.05648
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.05498
TF transferrin 1.05349
SCARB1 scavenger receptor class B, member 1 1.05349
AOC1 amine oxidase, copper containing 1 1.05237
IFRD1 interferon-related developmental regulator 1 1.05237
IRAK1 interleukin-1 receptor-associated kinase 1 1.05237
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.04904
TACR1 tachykinin receptor 1 1.04904
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 1.04757
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.04757
TGFA transforming growth factor, alpha 1.04647
CHUK conserved helix-loop-helix ubiquitous kinase 1.04647
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.04501
NGFR nerve growth factor receptor 1.04465
CDKN2A cyclin-dependent kinase inhibitor 2A 1.04427
DIO2 deiodinase, iodothyronine, type II 1.04163
PRKG1 protein kinase, cGMP-dependent, type I 1.04126
BAG1 BCL2-associated athanogene 1.04126
RXRG retinoid X receptor, gamma 1.04014
SQSTM1 sequestosome 1 1.03715
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.03604
EIF4E eukaryotic translation initiation factor 4E 1.03567
VEGFC vascular endothelial growth factor C 1.03567
PGK1 phosphoglycerate kinase 1 1.03419
ARRB1 arrestin, beta 1 1.03308
IDI1 isopentenyl-diphosphate delta isomerase 1 1.03046
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.03009
AVPR1A arginine vasopressin receptor 1A 1.03009
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 1.03009
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.02933
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.02821
RRM2 ribonucleotide reductase M2 1.02821
VGF VGF nerve growth factor inducible 1.02596
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.02596
SRXN1 sulfiredoxin 1 1.02522
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.02373
ALAS1 5'-aminolevulinate synthase 1 1.02373
PDIA3 protein disulfide isomerase family A, member 3 1.02003
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.01966
LIPE lipase, hormone-sensitive 1.01966
CGA glycoprotein hormones, alpha polypeptide 1.01966
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.01928
CARTPT CART prepropeptide 1.01928
GATA3 GATA binding protein 3 1.0189
IL12RB2 interleukin 12 receptor, beta 2 1.01663
CTH cystathionine gamma-lyase 1.01663
MYLK myosin light chain kinase 1.01474
RELN reelin 1.01437
ALAD aminolevulinate dehydratase 1.01324
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.01324
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.01249
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.01249
TPH2 tryptophan hydroxylase 2 1.01099