| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tadalafil perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tadalafil_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.142211 |
| FAM13A | family with sequence similarity 13, member A | 0.0894307 |
| HELZ | helicase with zinc finger | 0.0817912 |
| MEF2A | myocyte enhancer factor 2A | 0.0814589 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0677593 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0606375 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0485998 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0479969 |
| NDRG1 | N-myc downstream regulated 1 | 0.0440511 |
| FNBP1 | formin binding protein 1 | 0.039579 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0395222 |
| WAC | WW domain containing adaptor with coiled-coil | 0.038162 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0373069 |
| USP3 | ubiquitin specific peptidase 3 | 0.0359333 |
| WDR45B | WD repeat domain 45B | 0.0352472 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0348037 |
| XPO1 | exportin 1 | 0.0318395 |
| ZNF292 | zinc finger protein 292 | 0.0312463 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0309637 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0309 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0300568 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0299682 |
| RAB6A | RAB6A, member RAS oncogene family | 0.02962 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0293903 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0291478 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0288874 |
| NUP58 | nucleoporin 58 | 0.0287374 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0282119 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0273249 |
| MEIS2 | Meis homeobox 2 | 0.027089 |
| ZNF148 | zinc finger protein 148 | 0.0270446 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0269427 |
| SNX13 | sorting nexin 13 | 0.0268945 |
| CCNL1 | cyclin L1 | 0.0263545 |
| QKI | QKI, KH domain containing, RNA binding | 0.0263347 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0260882 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.025873 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0258632 |
| TLK2 | tousled-like kinase 2 | 0.0254467 |
| OGA | O-GlcNAcase | 0.0252057 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0248832 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0247606 |
| RIOK3 | RIO kinase 3 | 0.0245461 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0244607 |
| CDC73 | cell division cycle 73 | 0.0239211 |
| DTNA | dystrobrevin, alpha | 0.023635 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.023338 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0231523 |
| COPA | coatomer protein complex, subunit alpha | 0.0230252 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0229883 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0229871 |
| MINDY3 | MINDY lysine 48 deubiquitinase 3 | 0.0226339 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0225022 |
| RNF145 | ring finger protein 145 | 0.0224527 |
| RTN4 | reticulon 4 | 0.0221523 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0217969 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0213751 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.021186 |
| INSIG2 | insulin induced gene 2 | 0.0210371 |
| FOXO3 | forkhead box O3 | 0.0209603 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0209418 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0208186 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0207846 |
| ATP13A3 | ATPase type 13A3 | 0.0207304 |
| NEK7 | NIMA-related kinase 7 | 0.0206547 |
| TFG | TRK-fused gene | 0.0201952 |
| NGLY1 | N-glycanase 1 | 0.0199607 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0195907 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0195796 |
| CUL3 | cullin 3 | 0.0194313 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0192943 |
| CCNY | cyclin Y | 0.0192522 |
| GOLGA4 | golgin A4 | 0.0191033 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0188134 |
| RFX7 | regulatory factor X, 7 | 0.0187415 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.018684 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0184448 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0182703 |
| PTEN | phosphatase and tensin homolog | 0.0181359 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0180051 |
| YME1L1 | YME1-like 1 ATPase | 0.0179473 |
| DST | dystonin | 0.0178602 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0177336 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0176196 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0174598 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0173058 |
| USP12 | ubiquitin specific peptidase 12 | 0.017291 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0172461 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0171677 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0170354 |
| ASPH | aspartate beta-hydroxylase | 0.0168911 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0166621 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0162738 |
| CASC3 | cancer susceptibility candidate 3 | 0.0162568 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0162426 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0160353 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.016016 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0158892 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0158632 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0157729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.212055 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129984 |
| LSAMP | limbic system-associated membrane protein | -0.125687 |
| VCL | vinculin | -0.0900301 |
| VIM | vimentin | -0.082902 |
| ACTG1 | actin gamma 1 | -0.0607168 |
| NRG1 | neuregulin 1 | -0.0574515 |
| BPTF | bromodomain PHD finger transcription factor | -0.0548256 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0542601 |
| COL1A1 | collagen, type I, alpha 1 | -0.0534062 |
| RPLP1 | ribosomal protein, large, P1 | -0.0517946 |
| TLE4 | transducin-like enhancer of split 4 | -0.0448214 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0445561 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0438456 |
| RPS24 | ribosomal protein S24 | -0.0428807 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0392682 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0384854 |
| VMP1 | vacuole membrane protein 1 | -0.0367096 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0352846 |
| RPL34 | ribosomal protein L34 | -0.0340773 |
| RNF213 | ring finger protein 213 | -0.0316663 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0311976 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0297013 |
| THBS1 | thrombospondin 1 | -0.0296111 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.029439 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0293309 |
| DPH6 | diphthamine biosynthesis 6 | -0.0292673 |
| RPL19 | ribosomal protein L19 | -0.029195 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0290757 |
| PTMA | prothymosin, alpha | -0.0289732 |
| SYT1 | synaptotagmin I | -0.0288677 |
| EGR1 | early growth response 1 | -0.028511 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.028092 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0271126 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0269801 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0263875 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.026155 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.026077 |
| PRKCA | protein kinase C, alpha | -0.0252123 |
| RPLP0 | ribosomal protein, large, P0 | -0.02513 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0248669 |
| FMN1 | formin 1 | -0.0244854 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0242715 |
| RPL38 | ribosomal protein L38 | -0.0242068 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0238412 |
| TPM4 | tropomyosin 4 | -0.0237844 |
| KLHL13 | kelch-like family member 13 | -0.0237794 |
| RPL35A | ribosomal protein L35a | -0.0237036 |
| S100A9 | S100 calcium binding protein A9 | -0.0233392 |
| SMYD3 | SET and MYND domain containing 3 | -0.0233333 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0231972 |
| RPL30 | ribosomal protein L30 | -0.0224865 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0222488 |
| IER3 | immediate early response 3 | -0.0217547 |
| ZNF609 | zinc finger protein 609 | -0.0210178 |
| RPS19 | ribosomal protein S19 | -0.0209903 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0208352 |
| RPL31 | ribosomal protein L31 | -0.0207873 |
| AEBP2 | AE binding protein 2 | -0.0205968 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0205883 |
| RPL37A | ribosomal protein L37a | -0.0205006 |
| SEPTIN2 | septin 2 | -0.0203372 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0197761 |
| RPL7 | ribosomal protein L7 | -0.0196576 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0195499 |
| TMSB10 | thymosin beta 10 | -0.0195386 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0195071 |
| CUX1 | cut-like homeobox 1 | -0.0193449 |
| PCNX4 | pecanex 4 | -0.018865 |
| RPL12 | ribosomal protein L12 | -0.0184439 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0184288 |
| TPM1 | tropomyosin 1 (alpha) | -0.018306 |
| RPL36 | ribosomal protein L36 | -0.0182901 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0182178 |
| EHBP1 | EH domain binding protein 1 | -0.0181151 |
| GPC5 | glypican 5 | -0.0179009 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0178251 |
| GATA3 | GATA binding protein 3 | -0.0174644 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0174517 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0173971 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0171998 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0171525 |
| R3HDM2 | R3H domain containing 2 | -0.0170794 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0170121 |
| RPS23 | ribosomal protein S23 | -0.0169578 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.016917 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0168974 |
| RPL23 | ribosomal protein L23 | -0.0167513 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0166568 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0166108 |
| S100A6 | S100 calcium binding protein A6 | -0.0165193 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0164336 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0164322 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0164267 |
| DSTN | destrin (actin depolymerizing factor) | -0.0164014 |
| RPL26 | ribosomal protein L26 | -0.0163753 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0163639 |
| CFDP1 | craniofacial development protein 1 | -0.0161822 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0160969 |
| TBCA | tubulin folding cofactor A | -0.0160461 |
