| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tadalafil perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tadalafil_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0764104 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.061367 |
| RBM39 | RNA binding motif protein 39 | 0.0610315 |
| PGK1 | phosphoglycerate kinase 1 | 0.0600228 |
| FNDC3B | fibronectin type III domain containing 3B | 0.059582 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0586878 |
| TMSB10 | thymosin beta 10 | 0.0582337 |
| RPL35A | ribosomal protein L35a | 0.0571886 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0559017 |
| RNF145 | ring finger protein 145 | 0.0557027 |
| RPS12 | ribosomal protein S12 | 0.0548439 |
| MED13L | mediator complex subunit 13-like | 0.0530107 |
| RPS2 | ribosomal protein S2 | 0.0527315 |
| ONECUT3 | one cut homeobox 3 | 0.0512258 |
| RPS19 | ribosomal protein S19 | 0.0509088 |
| RPL37A | ribosomal protein L37a | 0.0504462 |
| RPS3 | ribosomal protein S3 | 0.0466445 |
| MT2A | metallothionein 2A | 0.0454836 |
| FAM13A | family with sequence similarity 13, member A | 0.0428699 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0426896 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0423539 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0422992 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0419311 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0411859 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0411685 |
| RPS23 | ribosomal protein S23 | 0.0410301 |
| RPS8 | ribosomal protein S8 | 0.0409142 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0397473 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0394143 |
| RPS29 | ribosomal protein S29 | 0.0387409 |
| RPL36 | ribosomal protein L36 | 0.0380071 |
| RPL34 | ribosomal protein L34 | 0.0378807 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0371342 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0370747 |
| S100P | S100 calcium binding protein P | 0.0370078 |
| MYO5B | myosin VB | 0.0366456 |
| RPS17 | ribosomal protein S17 | 0.0360869 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.035707 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0349779 |
| RPL26 | ribosomal protein L26 | 0.0348833 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0344599 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0342426 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0338011 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0330825 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0330724 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0328948 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0326079 |
| AHNAK | AHNAK nucleoprotein | 0.0318405 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0316645 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0315843 |
| NCKAP1 | NCK-associated protein 1 | 0.0315343 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.031342 |
| LRRC1 | leucine rich repeat containing 1 | 0.0313194 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0309003 |
| TFG | TRK-fused gene | 0.0304346 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0302775 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0296642 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0291231 |
| RPLP2 | ribosomal protein, large, P2 | 0.0288602 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.028578 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0283767 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0277796 |
| B2M | beta-2-microglobulin | 0.0270359 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0265737 |
| EREG | epiregulin | 0.0263488 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0263101 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0262302 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0261272 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0259111 |
| FOXJ3 | forkhead box J3 | 0.0258449 |
| RPL38 | ribosomal protein L38 | 0.0257402 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0255417 |
| CCNL1 | cyclin L1 | 0.0252535 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0250978 |
| AREG | amphiregulin | 0.0250774 |
| RAB21 | RAB21, member RAS oncogene family | 0.0249178 |
| AFDN | afadin, adherens junction formation factor | 0.024809 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0247566 |
| COPA | coatomer protein complex, subunit alpha | 0.0247552 |
| RPL4 | ribosomal protein L4 | 0.024401 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0243421 |
| RREB1 | ras responsive element binding protein 1 | 0.0242887 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0237251 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0236345 |
| PARD3 | par-3 family cell polarity regulator | 0.023493 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0232885 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0231406 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0228489 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0228292 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0227703 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0226677 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.022585 |
| CCNY | cyclin Y | 0.0225179 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.022483 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0224583 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0222927 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0222754 |
| ACTN4 | actinin, alpha 4 | 0.0219708 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0216651 |
| RPL30 | ribosomal protein L30 | 0.0215465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.246082 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.222485 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.158825 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.150452 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.13213 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.11082 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.104437 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0960732 |
| EZR | ezrin | -0.0950047 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0936405 |
| KRT18 | keratin 18, type I | -0.0912389 |
| TXNIP | thioredoxin interacting protein | -0.0855683 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0754689 |
| LDHA | lactate dehydrogenase A | -0.0657186 |
| DSPP | dentin sialophosphoprotein | -0.064327 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0573815 |
| HMGA1 | high mobility group AT-hook 1 | -0.0565045 |
| PTMA | prothymosin, alpha | -0.0563205 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0560927 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0560883 |
| PERP | PERP, TP53 apoptosis effector | -0.0545066 |
| GDF15 | growth differentiation factor 15 | -0.0534228 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.05313 |
| MED13 | mediator complex subunit 13 | -0.0488076 |
| RPLP0 | ribosomal protein, large, P0 | -0.0482023 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.046864 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0457261 |
| S100A6 | S100 calcium binding protein A6 | -0.0450644 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0449903 |
| PIGR | polymeric immunoglobulin receptor | -0.0442638 |
| MLEC | malectin | -0.0411926 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0410105 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0387514 |
| EMP1 | epithelial membrane protein 1 | -0.0386441 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0383872 |
| CALB1 | calbindin 1, 28kDa | -0.038226 |
| ITGA6 | integrin, alpha 6 | -0.0380675 |
| DSTN | destrin (actin depolymerizing factor) | -0.0377224 |
| KRT19 | keratin 19, type I | -0.0375219 |
| ANXA1 | annexin A1 | -0.0365103 |
| AGR2 | anterior gradient 2 | -0.0364384 |
| MUC17 | mucin 17, cell surface associated | -0.0361792 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0361111 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0358896 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0357363 |
| TPM4 | tropomyosin 4 | -0.0354712 |
| JUN | jun proto-oncogene | -0.0347288 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0346129 |
| EPCAM | epithelial cell adhesion molecule | -0.0346129 |
| ITGB4 | integrin, beta 4 | -0.0323491 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0323067 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0322701 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0318249 |
| FHL2 | four and a half LIM domains 2 | -0.0315223 |
| KLF6 | Kruppel-like factor 6 | -0.0308997 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0299503 |
| GPHN | gephyrin | -0.0298786 |
| CALR | calreticulin | -0.0292391 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0292176 |
| CD44 | CD44 molecule (Indian blood group) | -0.0288792 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0288461 |
| POTEF | POTE ankyrin domain family, member F | -0.0288265 |
| PFN1 | profilin 1 | -0.0285297 |
| SHROOM3 | shroom family member 3 | -0.0283058 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0279892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0278889 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0274299 |
| FBXO32 | F-box protein 32 | -0.0273715 |
| INSIG1 | insulin induced gene 1 | -0.0271545 |
| ACTG1 | actin gamma 1 | -0.0270139 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0270121 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0265678 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0262909 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.026066 |
| DENND4C | DENN/MADD domain containing 4C | -0.0260531 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0260209 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.025691 |
| CANX | calnexin | -0.0252402 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0250412 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0250183 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0245587 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0243693 |
| ABLIM1 | actin binding LIM protein 1 | -0.0243441 |
| DSG2 | desmoglein 2 | -0.0241591 |
| YBX1 | Y box binding protein 1 | -0.0234247 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0232193 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0231296 |
| MAGT1 | magnesium transporter 1 | -0.0230549 |
| TMEM135 | transmembrane protein 135 | -0.0228253 |
| KRT8 | keratin 8, type II | -0.0228102 |
| CLDN7 | claudin 7 | -0.0227754 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.022625 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0225408 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0225253 |
| TAGLN2 | transgelin 2 | -0.0224888 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0224261 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.022323 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.022316 |
| NFIA | nuclear factor I/A | -0.0219861 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0219144 |
