| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tadalafil perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tadalafil_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.14828 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.142023 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.119604 |
| ECT2 | epithelial cell transforming 2 | 0.116273 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.112607 |
| ZNF292 | zinc finger protein 292 | 0.107402 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.100123 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0934116 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0932336 |
| PDGFC | platelet derived growth factor C | 0.0898421 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0782604 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0752584 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0678978 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0678484 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0676841 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0673989 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0667621 |
| EVI5 | ecotropic viral integration site 5 | 0.0663862 |
| XPO1 | exportin 1 | 0.065785 |
| QKI | QKI, KH domain containing, RNA binding | 0.0654839 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0653488 |
| TJP1 | tight junction protein 1 | 0.06373 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0622122 |
| CDC73 | cell division cycle 73 | 0.0605688 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.059821 |
| HELZ | helicase with zinc finger | 0.0592394 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0584561 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0581714 |
| RBM39 | RNA binding motif protein 39 | 0.0568391 |
| PTMA | prothymosin, alpha | 0.056634 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0565612 |
| HDAC9 | histone deacetylase 9 | 0.0550021 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0540382 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0536627 |
| TXNIP | thioredoxin interacting protein | 0.0533223 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0529071 |
| TFG | TRK-fused gene | 0.0510835 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0492248 |
| MKI67 | marker of proliferation Ki-67 | 0.0486665 |
| CCNL1 | cyclin L1 | 0.0484625 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0481645 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0476502 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.047303 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0461796 |
| NUP58 | nucleoporin 58 | 0.0459005 |
| GOLGA4 | golgin A4 | 0.0457697 |
| MATR3 | matrin 3 | 0.0453398 |
| NCKAP1 | NCK-associated protein 1 | 0.0446794 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0445792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0443998 |
| PHIP | pleckstrin homology domain interacting protein | 0.0437044 |
| DIAPH3 | diaphanous-related formin 3 | 0.0435021 |
| YAP1 | Yes-associated protein 1 | 0.0432542 |
| SRPK2 | SRSF protein kinase 2 | 0.0432023 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0431067 |
| CENPF | centromere protein F, 350/400kDa | 0.0428048 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0422191 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0415476 |
| BMP10 | bone morphogenetic protein 10 | 0.0415296 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0415203 |
| PGK1 | phosphoglycerate kinase 1 | 0.0412613 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0409282 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0404293 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0403451 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0400493 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0397755 |
| PDS5B | PDS5 cohesin associated factor B | 0.0395704 |
| MED13L | mediator complex subunit 13-like | 0.0383941 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0378203 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0377311 |
| PTK2 | protein tyrosine kinase 2 | 0.0376151 |
| RYBP | RING1 and YY1 binding protein | 0.0375283 |
| VCL | vinculin | 0.0374019 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0370526 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0367696 |
| SEPTIN7 | septin 7 | 0.0367565 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0363617 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.036217 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0360147 |
| FAT1 | FAT atypical cadherin 1 | 0.0357937 |
| ANLN | anillin, actin binding protein | 0.0352824 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0351655 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0344435 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0344414 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.033972 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0338093 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0338032 |
| CKAP5 | cytoskeleton associated protein 5 | 0.033799 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0330222 |
| ENO1 | enolase 1, (alpha) | 0.032993 |
| POU2F1 | POU class 2 homeobox 1 | 0.0329697 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0328278 |
| NAV2 | neuron navigator 2 | 0.0325657 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0322208 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0320431 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0318597 |
| TPX2 | TPX2, microtubule-associated | 0.0317255 |
| RCOR1 | REST corepressor 1 | 0.031685 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0315908 |
| ZNF451 | zinc finger protein 451 | 0.0315317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111533 |
| S100A6 | S100 calcium binding protein A6 | -0.0777054 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0767336 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0686053 |
| ACTG1 | actin gamma 1 | -0.0629054 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0619424 |
| EGFR | epidermal growth factor receptor | -0.0591278 |
| TXNRD1 | thioredoxin reductase 1 | -0.0570644 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0547266 |
| TMSB4X | thymosin beta 4, X-linked | -0.0407807 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0401367 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0387967 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0387865 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.037728 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0363921 |
| ANK2 | ankyrin 2, neuronal | -0.0350602 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0335953 |
| OSMR | oncostatin M receptor | -0.0320515 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0315549 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0307232 |
| LDHA | lactate dehydrogenase A | -0.0296275 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0295677 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0288144 |
| GLI2 | GLI family zinc finger 2 | -0.0279671 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0273726 |
| DUSP6 | dual specificity phosphatase 6 | -0.0268176 |
| RPL12 | ribosomal protein L12 | -0.0267252 |
| HDLBP | high density lipoprotein binding protein | -0.0256241 |
| SQSTM1 | sequestosome 1 | -0.0249571 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0247993 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0247535 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0241086 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0227123 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0215142 |
| PLPP3 | phospholipid phosphatase 3 | -0.0215133 |
| HLA-B | major histocompatibility complex, class I, B | -0.0214488 |
| PKM | pyruvate kinase, muscle | -0.0210103 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0207324 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.020673 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0206214 |
| AHI1 | Abelson helper integration site 1 | -0.0205888 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0201426 |
| FLNB | filamin B, beta | -0.019808 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0194429 |
| RPL13A | ribosomal protein L13a | -0.0194207 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0193992 |
| CCND1 | cyclin D1 | -0.019353 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0191787 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0190103 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0184961 |
| RIGI | RNA sensor RIG-I | -0.0182321 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0182186 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0182024 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0180134 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0179795 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0179715 |
| HM13 | histocompatibility (minor) 13 | -0.0179292 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.017841 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0177072 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0173982 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0173337 |
| ATRN | attractin | -0.0170878 |
| LRRC7 | leucine rich repeat containing 7 | -0.0170264 |
| TRERF1 | transcriptional regulating factor 1 | -0.0167985 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.016542 |
| DUSP4 | dual specificity phosphatase 4 | -0.0165282 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0163422 |
| RACK1 | receptor for activated C kinase 1 | -0.016222 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0162159 |
| SMARCAD1 | SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 | -0.0160412 |
| ZNF248 | zinc finger protein 248 | -0.0159044 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0158856 |
| PMM2 | phosphomannomutase 2 | -0.0158346 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0158132 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.0157671 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0157068 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0154914 |
| FTL | ferritin, light polypeptide | -0.0153402 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0152875 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0152632 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0151747 |
| MTAP | methylthioadenosine phosphorylase | -0.0151392 |
| GLI3 | GLI family zinc finger 3 | -0.0151261 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0150307 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0148279 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0146964 |
| PTPRS | protein tyrosine phosphatase, receptor type, S | -0.0146422 |
| ATP9B | ATPase, class II, type 9B | -0.0145663 |
| CANX | calnexin | -0.0144974 |
| ARF1 | ADP-ribosylation factor 1 | -0.0144915 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0144672 |
| RRBP1 | ribosome binding protein 1 | -0.0143958 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0143679 |
| HDAC8 | histone deacetylase 8 | -0.0141824 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0141465 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0140595 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0140295 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.013966 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0139655 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.0139575 |
