| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tadalafil perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tadalafil_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD109 | CD109 molecule | 0.0648972 |
| MT2A | metallothionein 2A | 0.0606882 |
| SPAG9 | sperm associated antigen 9 | 0.0503507 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0461609 |
| RNF145 | ring finger protein 145 | 0.042547 |
| NDRG1 | N-myc downstream regulated 1 | 0.0423416 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0415934 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0401059 |
| OGA | O-GlcNAcase | 0.0384007 |
| RPS3 | ribosomal protein S3 | 0.0381753 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0379716 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0371133 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0368098 |
| NEK7 | NIMA-related kinase 7 | 0.0365478 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0360035 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.034248 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0338156 |
| AFDN | afadin, adherens junction formation factor | 0.0326297 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0310706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.029916 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0299088 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0298069 |
| HELZ | helicase with zinc finger | 0.0295695 |
| COPA | coatomer protein complex, subunit alpha | 0.0293915 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0289862 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0283712 |
| HDGF | hepatoma-derived growth factor | 0.0282547 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0279488 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0262673 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0260521 |
| TPR | translocated promoter region, nuclear basket protein | 0.0257856 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0251729 |
| CENPF | centromere protein F, 350/400kDa | 0.0251457 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0247788 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0247484 |
| RPS2 | ribosomal protein S2 | 0.0246936 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0244826 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0242634 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.024221 |
| SUCO | SUN domain containing ossification factor | 0.0240478 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0238299 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0235231 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0231118 |
| XPO1 | exportin 1 | 0.0229181 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0227816 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0227503 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0224871 |
| JMJD1C | jumonji domain containing 1C | 0.0218822 |
| GPC6 | glypican 6 | 0.0217979 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0217721 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0217221 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0217202 |
| CAB39 | calcium binding protein 39 | 0.0216907 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0216638 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0214539 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.021201 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0210742 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0209454 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0208731 |
| CEP192 | centrosomal protein 192kDa | 0.0208577 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.020711 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0205817 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0205521 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0204944 |
| SP3 | Sp3 transcription factor | 0.0204806 |
| YAP1 | Yes-associated protein 1 | 0.0203624 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0203115 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0200655 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0199802 |
| RANBP9 | RAN binding protein 9 | 0.019974 |
| RCOR1 | REST corepressor 1 | 0.0198419 |
| FOXO3 | forkhead box O3 | 0.0197401 |
| USP53 | ubiquitin specific peptidase 53 | 0.0196095 |
| FOXJ3 | forkhead box J3 | 0.0194493 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0194021 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0191962 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0191947 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.018947 |
| SNX13 | sorting nexin 13 | 0.0188855 |
| ATP11A | ATPase, class VI, type 11A | 0.0188756 |
| CUL3 | cullin 3 | 0.0187986 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0186892 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0186803 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0186578 |
| HYOU1 | hypoxia up-regulated 1 | 0.0185301 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0184311 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0184178 |
| PDZD8 | PDZ domain containing 8 | 0.0183104 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0181747 |
| CDK19 | cyclin-dependent kinase 19 | 0.0181512 |
| WDR45B | WD repeat domain 45B | 0.0180587 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0179862 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0179739 |
| CCNL1 | cyclin L1 | 0.0178063 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0178055 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0177902 |
| KIF16B | kinesin family member 16B | 0.0177842 |
| ORC4 | origin recognition complex, subunit 4 | 0.0176969 |
| PCNX1 | pecanex 1 | 0.0176849 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0176792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.186676 |
| NRG1 | neuregulin 1 | -0.183828 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.15458 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.147453 |
| HMGA2 | high mobility group AT-hook 2 | -0.102292 |
| ASPH | aspartate beta-hydroxylase | -0.101949 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100935 |
| CANX | calnexin | -0.0865279 |
| TMSB10 | thymosin beta 10 | -0.0805425 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0781861 |
| VIM | vimentin | -0.0762918 |
| S100A6 | S100 calcium binding protein A6 | -0.0753114 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0751242 |
| HLA-B | major histocompatibility complex, class I, B | -0.0736002 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0703682 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0669376 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0634141 |
| MAP1B | microtubule-associated protein 1B | -0.0619271 |
| SQSTM1 | sequestosome 1 | -0.0612028 |
| TMSB4X | thymosin beta 4, X-linked | -0.0587455 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0563994 |
| GLIS3 | GLIS family zinc finger 3 | -0.0562118 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0540181 |
| PTMA | prothymosin, alpha | -0.0514299 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0489675 |
| FTL | ferritin, light polypeptide | -0.0483001 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0481497 |
| SFTPA2 | surfactant protein A2 | -0.0446498 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0444371 |
| TMEM156 | transmembrane protein 156 | -0.0440852 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0420848 |
| SYT1 | synaptotagmin I | -0.0417836 |
| ITGA1 | integrin, alpha 1 | -0.0405412 |
| HMGA1 | high mobility group AT-hook 1 | -0.0402626 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0402285 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0399387 |
| FOXP1 | forkhead box P1 | -0.0396332 |
| RPS24 | ribosomal protein S24 | -0.0394725 |
| S100A10 | S100 calcium binding protein A10 | -0.0392772 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0368014 |
| B2M | beta-2-microglobulin | -0.0361712 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0359856 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0351988 |
| RAI14 | retinoic acid induced 14 | -0.0351229 |
| EREG | epiregulin | -0.0344801 |
| RPS6 | ribosomal protein S6 | -0.0342324 |
| VCL | vinculin | -0.0340901 |
| CTSD | cathepsin D | -0.0338993 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0334705 |
| ACTG1 | actin gamma 1 | -0.0329586 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0328484 |
| ARF1 | ADP-ribosylation factor 1 | -0.0325628 |
| ETV1 | ets variant 1 | -0.0325328 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0325022 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0323886 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0322409 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0322301 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0318726 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0316925 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0315045 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0312646 |
| IER3 | immediate early response 3 | -0.0306906 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0305538 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0301875 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0300598 |
| LMNA | lamin A/C | -0.0299579 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0294872 |
| KLHL5 | kelch-like family member 5 | -0.0291163 |
| YBX3 | Y box binding protein 3 | -0.0287946 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0284042 |
| DST | dystonin | -0.0283081 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0282733 |
| AHI1 | Abelson helper integration site 1 | -0.0281982 |
| LOC112694756 | uncharaterized LOC112694756 | -0.027973 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0279339 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0276518 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0268741 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0266344 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0266285 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264667 |
| NTN4 | netrin 4 | -0.0264659 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0263821 |
| TPI1 | triosephosphate isomerase 1 | -0.0262874 |
| RPL37 | ribosomal protein L37 | -0.0262271 |
| RPS21 | ribosomal protein S21 | -0.0262031 |
| SEPTIN9 | septin 9 | -0.026038 |
| RAB10 | RAB10, member RAS oncogene family | -0.025996 |
| RPLP0 | ribosomal protein, large, P0 | -0.0256863 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0253461 |
| RPS20 | ribosomal protein S20 | -0.0253043 |
| H1-0 | H1.0 linker histone | -0.0252863 |
| OSMR | oncostatin M receptor | -0.0249736 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0246931 |
| UBC | ubiquitin C | -0.0246506 |
| TMEM131 | transmembrane protein 131 | -0.0244759 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0243798 |
| RACK1 | receptor for activated C kinase 1 | -0.0243698 |
| BSG | basigin (Ok blood group) | -0.023852 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0237067 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0233742 |
