| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.151384 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0880365 |
| PTMA | prothymosin, alpha | 0.0828212 |
| SQSTM1 | sequestosome 1 | 0.0800812 |
| CAVIN1 | caveolae associated protein 1 | 0.0573818 |
| CSTB | cystatin B (stefin B) | 0.0552082 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0530961 |
| THBS2 | thrombospondin 2 | 0.0497224 |
| ACTG1 | actin gamma 1 | 0.0487412 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0486104 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.044258 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0441387 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0439744 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0423714 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0415412 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0415331 |
| FSTL1 | follistatin-like 1 | 0.0401232 |
| RPS3 | ribosomal protein S3 | 0.0398051 |
| TMSB4X | thymosin beta 4, X-linked | 0.0387553 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0382842 |
| LMNA | lamin A/C | 0.0382312 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0373406 |
| ANXA2 | annexin A2 | 0.0359723 |
| MT2A | metallothionein 2A | 0.0352408 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0342946 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0323216 |
| RPL12 | ribosomal protein L12 | 0.0319993 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0317512 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0309093 |
| PGK1 | phosphoglycerate kinase 1 | 0.0300868 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0294966 |
| KLF6 | Kruppel-like factor 6 | 0.0284903 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0282662 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0282122 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0280578 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0280235 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0274391 |
| CCND1 | cyclin D1 | 0.026962 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0266915 |
| S100A10 | S100 calcium binding protein A10 | 0.0266115 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0254021 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.024522 |
| RPS2 | ribosomal protein S2 | 0.0245184 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0241706 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0241273 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0239833 |
| HLA-E | major histocompatibility complex, class I, E | 0.0236371 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0234097 |
| RPL26 | ribosomal protein L26 | 0.0233201 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0227076 |
| HIP1 | huntingtin interacting protein 1 | 0.0226836 |
| RPS19 | ribosomal protein S19 | 0.0221141 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0215838 |
| TMEM263 | transmembrane protein 263 | 0.0213172 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0210302 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0209 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0208648 |
| CEP350 | centrosomal protein 350kDa | 0.0206665 |
| RACK1 | receptor for activated C kinase 1 | 0.0204709 |
| GOLGA4 | golgin A4 | 0.0202647 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0202535 |
| RPL37A | ribosomal protein L37a | 0.0199522 |
| CLINT1 | clathrin interactor 1 | 0.0198984 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0198624 |
| NEFL | neurofilament, light polypeptide | 0.019319 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | 0.0192035 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0192021 |
| HLA-B | major histocompatibility complex, class I, B | 0.0189423 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0188283 |
| UBE2I | ubiquitin-conjugating enzyme E2I | 0.0186823 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0184828 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0181617 |
| RPL19 | ribosomal protein L19 | 0.0180738 |
| CDK13 | cyclin-dependent kinase 13 | 0.0180546 |
| TLE4 | transducin-like enhancer of split 4 | 0.0179792 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.017944 |
| ARF1 | ADP-ribosylation factor 1 | 0.017933 |
| CDH13 | cadherin 13 | 0.0177704 |
| RPL32 | ribosomal protein L32 | 0.0173315 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0172998 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.017109 |
| HMBOX1 | homeobox containing 1 | 0.0169664 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0169135 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0167263 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0167204 |
| RPS8 | ribosomal protein S8 | 0.016652 |
| RPL4 | ribosomal protein L4 | 0.0164897 |
| PFDN2 | prefoldin subunit 2 | 0.0162705 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0162472 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.01621 |
| HDLBP | high density lipoprotein binding protein | 0.0161874 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0161743 |
| DTNA | dystrobrevin, alpha | 0.0160216 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0159605 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0159442 |
| FYTTD1 | forty-two-three domain containing 1 | 0.015867 |
| RPL36 | ribosomal protein L36 | 0.0157878 |
| SRGN | serglycin | 0.0156815 |
| DENND1A | DENN/MADD domain containing 1A | 0.0156532 |
| SRP9 | signal recognition particle 9kDa | 0.0154635 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.232901 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.172247 |
| UBC | ubiquitin C | -0.136007 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.12511 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0996243 |
| CD44 | CD44 molecule (Indian blood group) | -0.0883059 |
| PKM | pyruvate kinase, muscle | -0.0875022 |
| NDRG1 | N-myc downstream regulated 1 | -0.0797124 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0701302 |
| CALR | calreticulin | -0.0692632 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0686267 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0680632 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0665233 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0662763 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0661969 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0642179 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0631861 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0618454 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0605524 |
| MYADM | myeloid-associated differentiation marker | -0.0601759 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0593624 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0587451 |
| POTEF | POTE ankyrin domain family, member F | -0.0540228 |
| NAV1 | neuron navigator 1 | -0.0514821 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0485403 |
| LDHA | lactate dehydrogenase A | -0.048183 |
| COPA | coatomer protein complex, subunit alpha | -0.0474734 |
| COL1A2 | collagen, type I, alpha 2 | -0.0461031 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0451349 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0447004 |
| MAP1B | microtubule-associated protein 1B | -0.0433124 |
| COL5A1 | collagen, type V, alpha 1 | -0.0427317 |
| ZNF207 | zinc finger protein 207 | -0.0408852 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0402984 |
| VEGFA | vascular endothelial growth factor A | -0.0388842 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0384009 |
| LOX | lysyl oxidase | -0.0382734 |
| TAPBP | TAP binding protein (tapasin) | -0.0364582 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0364459 |
| TXNIP | thioredoxin interacting protein | -0.0364457 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0345166 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0340052 |
| SP3 | Sp3 transcription factor | -0.0335457 |
| FLNB | filamin B, beta | -0.0332384 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0330253 |
| FBN1 | fibrillin 1 | -0.0326804 |
| RUNX1 | runt-related transcription factor 1 | -0.0310153 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0301821 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0300047 |
| EGFR | epidermal growth factor receptor | -0.029073 |
| CANX | calnexin | -0.0289917 |
| COL5A2 | collagen, type V, alpha 2 | -0.0283806 |
| MX2 | MX dynamin-like GTPase 2 | -0.0279969 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0278161 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274785 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0270057 |
| SP100 | SP100 nuclear antigen | -0.026629 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0263808 |
| VIM | vimentin | -0.0260788 |
| CLIC4 | chloride intracellular channel 4 | -0.0259589 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0255037 |
| C1D | C1D nuclear receptor corepressor | -0.0253983 |
| TGFB1 | transforming growth factor, beta 1 | -0.0251424 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0251051 |
| OPTN | optineurin | -0.0239992 |
| TAGLN2 | transgelin 2 | -0.0239564 |
| NOTCH2 | notch 2 | -0.0235268 |
| SETX | senataxin | -0.0234265 |
| XPO1 | exportin 1 | -0.0231073 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0229088 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0225896 |
| TMSB10 | thymosin beta 10 | -0.0223035 |
| AXL | AXL receptor tyrosine kinase | -0.0222878 |
| GLIS3 | GLIS family zinc finger 3 | -0.0221909 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0221904 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0221894 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0221459 |
| LAMB1 | laminin, beta 1 | -0.0219869 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.021831 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0217986 |
| PRELID2 | PRELI domain containing 2 | -0.0217951 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0217406 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0217073 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0215308 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0215115 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0214924 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0212717 |
| TPM1 | tropomyosin 1 (alpha) | -0.0212452 |
| LOXL2 | lysyl oxidase-like 2 | -0.021196 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0211577 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0211094 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0208662 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.020117 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0197361 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | -0.019616 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0195926 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0195422 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0193951 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0193838 |
| SMIM44 | small integral membrane protein 44 | -0.0193032 |
