| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.18842 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.177114 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0886429 |
| H1-0 | H1.0 linker histone | 0.0774477 |
| GOLGB1 | golgin B1 | 0.0767047 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0742134 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0741019 |
| EZR | ezrin | 0.0730797 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0688752 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0687604 |
| CANX | calnexin | 0.0629782 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0609777 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0592803 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0580197 |
| SQSTM1 | sequestosome 1 | 0.0574406 |
| PHF3 | PHD finger protein 3 | 0.0561381 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0547706 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0544739 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.053741 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0533223 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0531528 |
| HDLBP | high density lipoprotein binding protein | 0.0522798 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.051637 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0493282 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0491859 |
| MKI67 | marker of proliferation Ki-67 | 0.0482774 |
| RUNX1 | runt-related transcription factor 1 | 0.0474808 |
| AHNAK | AHNAK nucleoprotein | 0.0453321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0448617 |
| CALU | calumenin | 0.044403 |
| DSPP | dentin sialophosphoprotein | 0.0400712 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0398197 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0397887 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0396294 |
| ANXA2 | annexin A2 | 0.039548 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0395072 |
| SEC24D | SEC24 family member D | 0.0393005 |
| TC2N | tandem C2 domains, nuclear | 0.0389505 |
| RNF43 | ring finger protein 43 | 0.0386547 |
| EHF | ets homologous factor | 0.0385479 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0383247 |
| IRF1 | interferon regulatory factor 1 | 0.0367224 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0362647 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0361849 |
| CENPF | centromere protein F, 350/400kDa | 0.0358654 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0357012 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0345776 |
| MORF4L2 | mortality factor 4 like 2 | 0.0345561 |
| EFNB2 | ephrin-B2 | 0.0344896 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0343299 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0340016 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0337549 |
| SEC24A | SEC24 family member A | 0.0337345 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0337179 |
| AGR2 | anterior gradient 2 | 0.0336173 |
| HLA-A | major histocompatibility complex, class I, A | 0.0331378 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0328434 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0325626 |
| PMM2 | phosphomannomutase 2 | 0.03252 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0325077 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0323565 |
| RRBP1 | ribosome binding protein 1 | 0.0322692 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0318113 |
| ANXA1 | annexin A1 | 0.0314245 |
| PRELID2 | PRELI domain containing 2 | 0.0312341 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.030557 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0305131 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0302624 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.029913 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0296811 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0296375 |
| RAD51B | RAD51 paralog B | 0.0294721 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0294694 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0293389 |
| SUCO | SUN domain containing ossification factor | 0.029002 |
| MEIS2 | Meis homeobox 2 | 0.0281299 |
| INTS6 | integrator complex subunit 6 | 0.0275106 |
| TMEM263 | transmembrane protein 263 | 0.0275069 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0274924 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0273263 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0273104 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0270712 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0267725 |
| KIAA1217 | KIAA1217 | 0.0265333 |
| ADIPOR2 | adiponectin receptor 2 | 0.0262823 |
| CDHR2 | cadherin-related family member 2 | 0.02615 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.026128 |
| MYO1E | myosin IE | 0.0261252 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0260516 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0259285 |
| MXI1 | MAX interactor 1, dimerization protein | 0.025782 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0256241 |
| ZNF841 | zinc finger protein 841 | 0.0256023 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0255575 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0253652 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0253541 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0253105 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0252287 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0248821 |
| FNIP1 | folliculin interacting protein 1 | 0.02486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.128443 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.113629 |
| LYZ | lysozyme | -0.110775 |
| LCN2 | lipocalin 2 | -0.0907986 |
| RNF213 | ring finger protein 213 | -0.0884238 |
| ERBIN | erbb2 interacting protein | -0.0794763 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.072624 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0672289 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0644638 |
| MX1 | MX dynamin-like GTPase 1 | -0.062092 |
| MX2 | MX dynamin-like GTPase 2 | -0.0569439 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0565493 |
| NPSR1 | neuropeptide S receptor 1 | -0.0563258 |
| MSI2 | musashi RNA-binding protein 2 | -0.0535024 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0521608 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.050653 |
| RIGI | RNA sensor RIG-I | -0.0470374 |
| ITGA6 | integrin, alpha 6 | -0.046825 |
| PRKCA | protein kinase C, alpha | -0.0464824 |
| LAMA4 | laminin, alpha 4 | -0.0462423 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0459024 |
| VCL | vinculin | -0.0450613 |
| PKM | pyruvate kinase, muscle | -0.0446729 |
| SP100 | SP100 nuclear antigen | -0.0417996 |
| POTEF | POTE ankyrin domain family, member F | -0.0388987 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0387368 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0386693 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0382356 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0379789 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0374171 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0373003 |
| TJP1 | tight junction protein 1 | -0.0340873 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0339259 |
| PERP | PERP, TP53 apoptosis effector | -0.0334975 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0332336 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0331126 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0328252 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0325095 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0319899 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0318044 |
| EFHD2 | EF-hand domain family, member D2 | -0.0317549 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0309047 |
| SETX | senataxin | -0.029095 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0290941 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0278801 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0277332 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0275141 |
| BCL2L1 | BCL2-like 1 | -0.0273728 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0273728 |
| ATP11A | ATPase, class VI, type 11A | -0.0271989 |
| CTSD | cathepsin D | -0.0267253 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0266324 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0256641 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0256193 |
| ZNF148 | zinc finger protein 148 | -0.0255715 |
| UBAP2 | ubiquitin associated protein 2 | -0.0255274 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0254707 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.025464 |
| TMSB10 | thymosin beta 10 | -0.0249788 |
| PLSCR2 | phospholipid scramblase 2 | -0.0248816 |
| RPL35A | ribosomal protein L35a | -0.0245514 |
| TXNRD1 | thioredoxin reductase 1 | -0.0243385 |
| PSEN1 | presenilin 1 | -0.0242721 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0241551 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.024003 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0238033 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0236827 |
| FTL | ferritin, light polypeptide | -0.0234757 |
| ZNF207 | zinc finger protein 207 | -0.0231536 |
| PNN | pinin, desmosome associated protein | -0.0231151 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0230895 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.022876 |
| LIMA1 | LIM domain and actin binding 1 | -0.022711 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0226996 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0226366 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0225809 |
| PMP22 | peripheral myelin protein 22 | -0.0223442 |
| TXNIP | thioredoxin interacting protein | -0.0223176 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0222994 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0221837 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.022071 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0220381 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0219187 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0215509 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0209675 |
| ACTG1 | actin gamma 1 | -0.0207952 |
| FNDC3A | fibronectin type III domain containing 3A | -0.020664 |
| NAV1 | neuron navigator 1 | -0.0205562 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0203494 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.02029 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0202366 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0201594 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0201326 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0198032 |
| ETV6 | ets variant 6 | -0.0195493 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0194231 |
| PFN1 | profilin 1 | -0.0193624 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0193547 |
| RBM25 | RNA binding motif protein 25 | -0.0193542 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0192419 |
