| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0595605 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.051008 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0509106 |
| KRT17 | keratin 17, type I | 0.0348054 |
| TGM2 | transglutaminase 2 | 0.0340058 |
| H1-0 | H1.0 linker histone | 0.0322649 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0298439 |
| ANXA1 | annexin A1 | 0.0292986 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0286435 |
| ARRDC3 | arrestin domain containing 3 | 0.0280144 |
| MEF2A | myocyte enhancer factor 2A | 0.0269714 |
| PRELID2 | PRELI domain containing 2 | 0.0257409 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0235292 |
| FNIP1 | folliculin interacting protein 1 | 0.0232688 |
| SRP54 | signal recognition particle 54kDa | 0.0230852 |
| OGA | O-GlcNAcase | 0.0230471 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0229469 |
| YBX3 | Y box binding protein 3 | 0.0228769 |
| RPS2 | ribosomal protein S2 | 0.0223697 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0221601 |
| STC1 | stanniocalcin 1 | 0.019968 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0199499 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0194133 |
| RPL4 | ribosomal protein L4 | 0.0190543 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0190335 |
| DUSP6 | dual specificity phosphatase 6 | 0.0184905 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0177681 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0176937 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0170621 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0168327 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0168068 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0167593 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0166592 |
| HELZ | helicase with zinc finger | 0.0163445 |
| METTL15 | methyltransferase like 15 | 0.0162569 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0156824 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0156375 |
| FLNA | filamin A, alpha | 0.0155921 |
| RPL3 | ribosomal protein L3 | 0.015342 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0152806 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0151423 |
| HLA-A | major histocompatibility complex, class I, A | 0.0148354 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0148309 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0147246 |
| YEATS2 | YEATS domain containing 2 | 0.0145968 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0143393 |
| C1D | C1D nuclear receptor corepressor | 0.0137804 |
| GOLGA4 | golgin A4 | 0.0136251 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0135866 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0135683 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0130053 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0130038 |
| MXI1 | MAX interactor 1, dimerization protein | 0.012745 |
| BARX2 | BARX homeobox 2 | 0.0126868 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0125707 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0124878 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0124475 |
| SUCO | SUN domain containing ossification factor | 0.0122962 |
| KIF16B | kinesin family member 16B | 0.0122244 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0118374 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0117943 |
| RNF19B | ring finger protein 19B | 0.0116809 |
| CREB1 | cAMP responsive element binding protein 1 | 0.011677 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0114737 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.011465 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0113925 |
| TMEM263 | transmembrane protein 263 | 0.0111885 |
| ABHD17C | abhydrolase domain containing 17C | 0.0110785 |
| SEC24A | SEC24 family member A | 0.0109941 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0109682 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0109423 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0109365 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0107388 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0107188 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0107036 |
| TMEM39A | transmembrane protein 39A | 0.0105927 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0105246 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0101911 |
| SCFD1 | sec1 family domain containing 1 | 0.010068 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0100495 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0100116 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.00998537 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.00997904 |
| MLF1 | myeloid leukemia factor 1 | 0.0098568 |
| MYO9A | myosin IXA | 0.00980386 |
| PLPP1 | phospholipid phosphatase 1 | 0.00979536 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.00977472 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.00973153 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00966306 |
| ANXA4 | annexin A4 | 0.00963459 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00955082 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00953946 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00949256 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.00942377 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00941015 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.00938314 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.00937767 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.00937536 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.00935512 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00926948 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.295206 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.159693 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.133909 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0928306 |
| POTEF | POTE ankyrin domain family, member F | -0.0767699 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0750832 |
| ITGA6 | integrin, alpha 6 | -0.0729531 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0707095 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0589894 |
| SULF1 | sulfatase 1 | -0.0578263 |
| SULF2 | sulfatase 2 | -0.0545872 |
| CD44 | CD44 molecule (Indian blood group) | -0.0543185 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0539304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0535899 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0509346 |
| MTSS1 | metastasis suppressor 1 | -0.0499062 |
| RPS21 | ribosomal protein S21 | -0.049175 |
| LDHA | lactate dehydrogenase A | -0.0488988 |
| PODXL | podocalyxin-like | -0.0487107 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0483529 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0482584 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0480305 |
| B2M | beta-2-microglobulin | -0.0477401 |
| ASPH | aspartate beta-hydroxylase | -0.0472696 |
| HLA-B | major histocompatibility complex, class I, B | -0.0467053 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0463798 |
| TMSB4X | thymosin beta 4, X-linked | -0.0462103 |
| ACTN4 | actinin, alpha 4 | -0.0457069 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0452427 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0445669 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0439371 |
| LAMC2 | laminin, gamma 2 | -0.0434548 |
| IGF2 | insulin-like growth factor 2 | -0.0432493 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0428232 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0427173 |
| RASAL2 | RAS protein activator like 2 | -0.0422757 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0409025 |
| TXNIP | thioredoxin interacting protein | -0.0395719 |
| LMO7 | LIM domain 7 | -0.0384219 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0377274 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0375661 |
| PGK1 | phosphoglycerate kinase 1 | -0.0375051 |
| AHNAK | AHNAK nucleoprotein | -0.0373977 |
| CDK6 | cyclin-dependent kinase 6 | -0.0368968 |
| RIGI | RNA sensor RIG-I | -0.0365349 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0363614 |
| FOXP1 | forkhead box P1 | -0.0362905 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0362706 |
| JMJD1C | jumonji domain containing 1C | -0.0361105 |
| ENO1 | enolase 1, (alpha) | -0.0360621 |
| RPS13 | ribosomal protein S13 | -0.0358596 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.035497 |
| PTK2 | protein tyrosine kinase 2 | -0.0350843 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0350817 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0336661 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0334445 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0328689 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0323153 |
| HMGA2 | high mobility group AT-hook 2 | -0.0322983 |
| UBC | ubiquitin C | -0.0320218 |
| PKM | pyruvate kinase, muscle | -0.0319609 |
| VCL | vinculin | -0.0319078 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0318688 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0314053 |
| S100A10 | S100 calcium binding protein A10 | -0.0309754 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0307012 |
| TXNRD1 | thioredoxin reductase 1 | -0.0305202 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0302745 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0299833 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0298275 |
| CDCP1 | CUB domain containing protein 1 | -0.0296389 |
| ECE1 | endothelin converting enzyme 1 | -0.029333 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0290425 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0289397 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0288603 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0286567 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0286209 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0285524 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0284901 |
| RCOR1 | REST corepressor 1 | -0.0284176 |
| RPS24 | ribosomal protein S24 | -0.0283014 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0282259 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.027856 |
| TPM4 | tropomyosin 4 | -0.0276737 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0270556 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0269724 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.026949 |
| EMP1 | epithelial membrane protein 1 | -0.0268797 |
| PRSS23 | protease, serine, 23 | -0.0268335 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0266642 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0265662 |
| EGR1 | early growth response 1 | -0.0263025 |
| FLNB | filamin B, beta | -0.0258584 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0258309 |
| BLCAP | bladder cancer associated protein | -0.0258012 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0256971 |
| HMGA1 | high mobility group AT-hook 1 | -0.025526 |
| HDAC9 | histone deacetylase 9 | -0.0254933 |
| CLIC4 | chloride intracellular channel 4 | -0.0254884 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.02531 |
