| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.321889 |
| PTMA | prothymosin, alpha | 0.0773086 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0679102 |
| H1-0 | H1.0 linker histone | 0.063546 |
| ANXA1 | annexin A1 | 0.0561329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0554609 |
| HM13 | histocompatibility (minor) 13 | 0.0539382 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0537636 |
| GOLGA4 | golgin A4 | 0.0526814 |
| RPS3 | ribosomal protein S3 | 0.0522531 |
| NPSR1 | neuropeptide S receptor 1 | 0.0454662 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0413572 |
| AGR3 | anterior gradient 3 | 0.0413369 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0400064 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0395868 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0340446 |
| PGK1 | phosphoglycerate kinase 1 | 0.0337979 |
| RPL18 | ribosomal protein L18 | 0.033506 |
| FAM13A | family with sequence similarity 13, member A | 0.0330418 |
| SRP54 | signal recognition particle 54kDa | 0.0327064 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0322488 |
| PMM2 | phosphomannomutase 2 | 0.0320755 |
| RPL4 | ribosomal protein L4 | 0.0320666 |
| HLA-A | major histocompatibility complex, class I, A | 0.031529 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0309913 |
| TMF1 | TATA element modulatory factor 1 | 0.0309474 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0307096 |
| CDK13 | cyclin-dependent kinase 13 | 0.0298671 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0297027 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0291846 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0290123 |
| MORF4L2 | mortality factor 4 like 2 | 0.0284634 |
| AREG | amphiregulin | 0.0279354 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0274682 |
| GOLGB1 | golgin B1 | 0.0273608 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0259038 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0257974 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0257446 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0255178 |
| COG5 | component of oligomeric golgi complex 5 | 0.0254316 |
| RBM39 | RNA binding motif protein 39 | 0.0247763 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0247558 |
| ANXA2 | annexin A2 | 0.0244101 |
| ENO1 | enolase 1, (alpha) | 0.0240141 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0238266 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0235743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0235661 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0234517 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.023043 |
| HKDC1 | hexokinase domain containing 1 | 0.0228613 |
| RPL37A | ribosomal protein L37a | 0.0227793 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0225824 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0224947 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0224875 |
| KRT17 | keratin 17, type I | 0.0223274 |
| RPS12 | ribosomal protein S12 | 0.0221736 |
| PGM3 | phosphoglucomutase 3 | 0.0221613 |
| MUC17 | mucin 17, cell surface associated | 0.0221536 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0220129 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0219646 |
| SETD5 | SET domain containing 5 | 0.0219137 |
| DSG2 | desmoglein 2 | 0.0218872 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0210886 |
| KLHL29 | kelch-like family member 29 | 0.0208376 |
| FNIP1 | folliculin interacting protein 1 | 0.0207364 |
| RPS2 | ribosomal protein S2 | 0.0206642 |
| EHBP1 | EH domain binding protein 1 | 0.0206529 |
| CANX | calnexin | 0.0203025 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0200496 |
| ZNF706 | zinc finger protein 706 | 0.0198799 |
| CYCS | cytochrome c, somatic | 0.0198567 |
| LAMB3 | laminin, beta 3 | 0.019788 |
| OSBPL2 | oxysterol binding protein-like 2 | 0.0197487 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0197306 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0195698 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0194947 |
| SRPRA | SRP receptor subunit alpha | 0.0192774 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0192202 |
| AHNAK | AHNAK nucleoprotein | 0.0191604 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.019081 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0188305 |
| PREPL | prolyl endopeptidase-like | 0.0186015 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0185779 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0185587 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0182108 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.018082 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0180714 |
| SELENOK | selenoprotein K | 0.0179426 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0177429 |
| SCFD1 | sec1 family domain containing 1 | 0.0176556 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.017576 |
| PAPOLA | poly(A) polymerase alpha | 0.0175226 |
| ARFGEF3 | ARFGEF family member 3 | 0.0173227 |
| TPM3 | tropomyosin 3 | 0.0172886 |
| PCBP1 | poly(rC) binding protein 1 | 0.0172342 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.017075 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0170017 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.0164893 |
| HDLBP | high density lipoprotein binding protein | 0.0163329 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0162431 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.111333 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0811775 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0772633 |
| TMSB10 | thymosin beta 10 | -0.0714685 |
| RPL35A | ribosomal protein L35a | -0.0616341 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0601497 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0585329 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.052113 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0477253 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0457722 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0412447 |
| KRT8 | keratin 8, type II | -0.0401105 |
| MUC1 | mucin 1, cell surface associated | -0.0397623 |
| CALR | calreticulin | -0.039747 |
| CLDN4 | claudin 4 | -0.0394701 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0382067 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0347362 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0342499 |
| EGR1 | early growth response 1 | -0.0341585 |
| RPS21 | ribosomal protein S21 | -0.0341254 |
| WWC1 | WW and C2 domain containing 1 | -0.0337687 |
| ACTN4 | actinin, alpha 4 | -0.032282 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0316439 |
| RPL38 | ribosomal protein L38 | -0.0306691 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0306129 |
| TXNRD1 | thioredoxin reductase 1 | -0.0305538 |
| FAT1 | FAT atypical cadherin 1 | -0.0289797 |
| PKM | pyruvate kinase, muscle | -0.0276602 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0276132 |
| STK24 | serine/threonine kinase 24 | -0.0271634 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0268584 |
| BCL2L1 | BCL2-like 1 | -0.0261695 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0259479 |
| INSIG1 | insulin induced gene 1 | -0.0257437 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0256031 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0254283 |
| B2M | beta-2-microglobulin | -0.0251671 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0250857 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.025014 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.024509 |
| NDRG1 | N-myc downstream regulated 1 | -0.0244897 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0243852 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0234308 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.023215 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0228614 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0227874 |
| ATP11A | ATPase, class VI, type 11A | -0.0226335 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0224305 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0222997 |
| TMC5 | transmembrane channel-like 5 | -0.0221949 |
| ATF5 | activating transcription factor 5 | -0.0221898 |
| ASPH | aspartate beta-hydroxylase | -0.0218953 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0215801 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0215487 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0210806 |
| RBM47 | RNA binding motif protein 47 | -0.0209263 |
| GPX2 | glutathione peroxidase 2 | -0.020747 |
| RNF213 | ring finger protein 213 | -0.0206891 |
| ITGA6 | integrin, alpha 6 | -0.0204723 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0204632 |
| SEPTIN9 | septin 9 | -0.0204414 |
| EPCAM | epithelial cell adhesion molecule | -0.0203516 |
| YAP1 | Yes-associated protein 1 | -0.0202487 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0200947 |
| RNF43 | ring finger protein 43 | -0.0197778 |
| CBX3 | chromobox homolog 3 | -0.0195652 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0193989 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0191518 |
| KRT19 | keratin 19, type I | -0.0190092 |
| BPTF | bromodomain PHD finger transcription factor | -0.0190023 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0187909 |
| RPLP1 | ribosomal protein, large, P1 | -0.0185912 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.018551 |
| H3-3B | H3.3 histone B | -0.018411 |
| S100A9 | S100 calcium binding protein A9 | -0.018389 |
| POTEF | POTE ankyrin domain family, member F | -0.0182013 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0181677 |
| ANXA11 | annexin A11 | -0.018006 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0179096 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0178702 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0178026 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0177798 |
| TFF2 | trefoil factor 2 | -0.017709 |
| PRELID2 | PRELI domain containing 2 | -0.0176733 |
| RPL23 | ribosomal protein L23 | -0.0176628 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0175331 |
| ITGB4 | integrin, beta 4 | -0.0175248 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0175242 |
| S100A10 | S100 calcium binding protein A10 | -0.0174698 |
| TC2N | tandem C2 domains, nuclear | -0.0174376 |
| JUP | junction plakoglobin | -0.0172867 |
| TNS4 | tensin 4 | -0.0172454 |
| LIMA1 | LIM domain and actin binding 1 | -0.017191 |
| IER3 | immediate early response 3 | -0.0171596 |
| LIPH | lipase, member H | -0.0171068 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0170507 |
| TMEM45B | transmembrane protein 45B | -0.0170454 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.01696 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0169293 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0168439 |
