| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.13397 |
| RPS2 | ribosomal protein S2 | 0.113194 |
| ANXA1 | annexin A1 | 0.101255 |
| EZR | ezrin | 0.0968313 |
| FAM13A | family with sequence similarity 13, member A | 0.0775486 |
| H1-0 | H1.0 linker histone | 0.073714 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0665787 |
| PTMA | prothymosin, alpha | 0.064902 |
| ANXA2 | annexin A2 | 0.0633191 |
| PIGR | polymeric immunoglobulin receptor | 0.062782 |
| DSPP | dentin sialophosphoprotein | 0.0609925 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0543165 |
| LMO7 | LIM domain 7 | 0.0534714 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0515094 |
| EMP1 | epithelial membrane protein 1 | 0.0510754 |
| RPL12 | ribosomal protein L12 | 0.048615 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.045062 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0443092 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0436679 |
| RPL18 | ribosomal protein L18 | 0.0428806 |
| KLF6 | Kruppel-like factor 6 | 0.0416989 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0415133 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0398725 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0390043 |
| DSG2 | desmoglein 2 | 0.0381697 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0373637 |
| ATF4 | activating transcription factor 4 | 0.0373007 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0371505 |
| WASF2 | WAS protein family, member 2 | 0.0370557 |
| RNF145 | ring finger protein 145 | 0.0363341 |
| RPL3 | ribosomal protein L3 | 0.0350972 |
| ZNF292 | zinc finger protein 292 | 0.0349387 |
| RACK1 | receptor for activated C kinase 1 | 0.0346281 |
| USP6NL | USP6 N-terminal like | 0.0342675 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0338297 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0336628 |
| ITGA6 | integrin, alpha 6 | 0.0333986 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0324162 |
| GDF15 | growth differentiation factor 15 | 0.0323596 |
| EREG | epiregulin | 0.032254 |
| RPL36 | ribosomal protein L36 | 0.0322524 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0320938 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.032062 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0316402 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0311205 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.030442 |
| RORA | RAR-related orphan receptor A | 0.0304167 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0303259 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0302849 |
| KITLG | KIT ligand | 0.0298563 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0297943 |
| RPS3 | ribosomal protein S3 | 0.0293607 |
| CCNY | cyclin Y | 0.0292062 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0288395 |
| FBXO32 | F-box protein 32 | 0.0286501 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0284637 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0282544 |
| PER2 | period circadian clock 2 | 0.0279672 |
| RPL4 | ribosomal protein L4 | 0.0276285 |
| MUC17 | mucin 17, cell surface associated | 0.0270862 |
| MLF1 | myeloid leukemia factor 1 | 0.026185 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0261081 |
| TPD52 | tumor protein D52 | 0.0260494 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0260491 |
| CCNL1 | cyclin L1 | 0.0255262 |
| RPL6 | ribosomal protein L6 | 0.0254307 |
| EXPH5 | exophilin 5 | 0.0253936 |
| HELZ | helicase with zinc finger | 0.0249092 |
| SHROOM3 | shroom family member 3 | 0.0248407 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0247735 |
| CASZ1 | castor zinc finger 1 | 0.0241634 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0240852 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0240748 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0240463 |
| RPL32 | ribosomal protein L32 | 0.023904 |
| YBX3 | Y box binding protein 3 | 0.0237888 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0237352 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0237039 |
| NUP54 | nucleoporin 54kDa | 0.0234974 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0232458 |
| RPS12 | ribosomal protein S12 | 0.0232137 |
| MUC13 | mucin 13, cell surface associated | 0.0230014 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0226975 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0226601 |
| H1-4 | H1.4 linker histone, cluster member | 0.0225584 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0223735 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0222466 |
| GATA6 | GATA binding protein 6 | 0.0218963 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0218156 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0214615 |
| TRIB1 | tribbles pseudokinase 1 | 0.0214282 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.02122 |
| ATF3 | activating transcription factor 3 | 0.0211529 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0206183 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0205478 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0204085 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0201935 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0201346 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0200588 |
| LRRC1 | leucine rich repeat containing 1 | 0.0200401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.243503 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.196997 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.144953 |
| TMSB10 | thymosin beta 10 | -0.113069 |
| UBC | ubiquitin C | -0.101009 |
| CALR | calreticulin | -0.0940725 |
| RPL35A | ribosomal protein L35a | -0.0893498 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0805071 |
| VCL | vinculin | -0.0792764 |
| RPS27A | ribosomal protein S27a | -0.0779402 |
| TPM4 | tropomyosin 4 | -0.0767292 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0756619 |
| PKM | pyruvate kinase, muscle | -0.0697528 |
| AHNAK | AHNAK nucleoprotein | -0.0651863 |
| NPSR1 | neuropeptide S receptor 1 | -0.0624902 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0618364 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0612088 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0607238 |
| RPS8 | ribosomal protein S8 | -0.0605321 |
| RPS24 | ribosomal protein S24 | -0.060447 |
| ACTG1 | actin gamma 1 | -0.0599249 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0543476 |
| KRT8 | keratin 8, type II | -0.0535428 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0530593 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0525941 |
| RPL31 | ribosomal protein L31 | -0.0491982 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0487231 |
| RPLP2 | ribosomal protein, large, P2 | -0.0486538 |
| RPL23 | ribosomal protein L23 | -0.0469842 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0461752 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0459351 |
| DIAPH2 | diaphanous-related formin 2 | -0.044539 |
| RPS13 | ribosomal protein S13 | -0.0435706 |
| RPL9 | ribosomal protein L9 | -0.0429468 |
| FHIT | fragile histidine triad | -0.041664 |
| POTEF | POTE ankyrin domain family, member F | -0.0409006 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0399339 |
| FTL | ferritin, light polypeptide | -0.0388883 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0379476 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.037629 |
| CANX | calnexin | -0.0373723 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0369995 |
| MAP4 | microtubule-associated protein 4 | -0.0368577 |
| TFF1 | trefoil factor 1 | -0.0365569 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.03611 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0360877 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0358284 |
| DEK | DEK proto-oncogene | -0.0353872 |
| PATJ | PATJ crumbs cell polarity complex component | -0.035056 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0348007 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0345453 |
| RPL7A | ribosomal protein L7a | -0.0341839 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0337344 |
| TPM1 | tropomyosin 1 (alpha) | -0.0335372 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0334559 |
| RPS25 | ribosomal protein S25 | -0.032721 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0322908 |
| HM13 | histocompatibility (minor) 13 | -0.0316831 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0314802 |
| IER3 | immediate early response 3 | -0.0314499 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0312325 |
| S100A6 | S100 calcium binding protein A6 | -0.030771 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305232 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0304434 |
| CCND1 | cyclin D1 | -0.0303219 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0298804 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0296421 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0293474 |
| RPS29 | ribosomal protein S29 | -0.0290744 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.028628 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0285451 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0284653 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0283883 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0281118 |
| EGFR | epidermal growth factor receptor | -0.0280804 |
| RPS23 | ribosomal protein S23 | -0.0279821 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0279686 |
| ENO1 | enolase 1, (alpha) | -0.0278451 |
| PALLD | palladin, cytoskeletal associated protein | -0.0278171 |
| ABR | active BCR-related | -0.0277526 |
| ETV6 | ets variant 6 | -0.0275963 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0272302 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0270172 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0269278 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0268249 |
| NUCB2 | nucleobindin 2 | -0.0267139 |
| RPL38 | ribosomal protein L38 | -0.0261796 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0261287 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0261275 |
| FRMD5 | FERM domain containing 5 | -0.0259141 |
| LDHA | lactate dehydrogenase A | -0.0256926 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0255249 |
| KRT18 | keratin 18, type I | -0.0254736 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.025337 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0252639 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0252076 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0251826 |
| RPL15 | ribosomal protein L15 | -0.0251521 |
| ANKRD17 | ankyrin repeat domain 17 | -0.025128 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0247118 |
