| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.198334 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0952146 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0813741 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.067522 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.06724 |
| FAM13A | family with sequence similarity 13, member A | 0.0634814 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0524719 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0510794 |
| SMAD3 | SMAD family member 3 | 0.0479926 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0474616 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0469433 |
| EFNA5 | ephrin-A5 | 0.0453054 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0441917 |
| RPL4 | ribosomal protein L4 | 0.0428866 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0428173 |
| CD44 | CD44 molecule (Indian blood group) | 0.0418363 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0404165 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0395686 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0392827 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0390677 |
| GOLGA4 | golgin A4 | 0.0377593 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0372339 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0362679 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0357136 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0353968 |
| RPS2 | ribosomal protein S2 | 0.0353816 |
| MT2A | metallothionein 2A | 0.0352207 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0334892 |
| RPS12 | ribosomal protein S12 | 0.0328236 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0326949 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0326167 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0305135 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0303326 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0294524 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0290328 |
| PRELID2 | PRELI domain containing 2 | 0.0287842 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0287549 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0285831 |
| OGA | O-GlcNAcase | 0.0285328 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0284711 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0282574 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281885 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.027909 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0276948 |
| ATP13A3 | ATPase type 13A3 | 0.0274609 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0273109 |
| USP34 | ubiquitin specific peptidase 34 | 0.0270086 |
| RPS3 | ribosomal protein S3 | 0.0268529 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0268104 |
| TGM2 | transglutaminase 2 | 0.0262524 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.025802 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0257649 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0256642 |
| PTMA | prothymosin, alpha | 0.0253173 |
| PCBP2 | poly(rC) binding protein 2 | 0.025226 |
| SERINC1 | serine incorporator 1 | 0.0245752 |
| OSMR | oncostatin M receptor | 0.0245329 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0245195 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0242344 |
| NAV2 | neuron navigator 2 | 0.0241933 |
| SBF2 | SET binding factor 2 | 0.0241001 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0240812 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0238386 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0237844 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0236443 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0235902 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0235667 |
| NEK7 | NIMA-related kinase 7 | 0.0234387 |
| KLF6 | Kruppel-like factor 6 | 0.0232208 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0227055 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0222551 |
| NCKAP1 | NCK-associated protein 1 | 0.0221123 |
| YEATS2 | YEATS domain containing 2 | 0.0220746 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0219622 |
| TMEM263 | transmembrane protein 263 | 0.0218236 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0213201 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0211315 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0210578 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0209041 |
| FAM107B | family with sequence similarity 107, member B | 0.0208857 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0207447 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0206876 |
| RBM39 | RNA binding motif protein 39 | 0.0205983 |
| HAS2 | hyaluronan synthase 2 | 0.0205475 |
| ANXA1 | annexin A1 | 0.0204607 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0204407 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0203317 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0202579 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0201646 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0199289 |
| VMP1 | vacuole membrane protein 1 | 0.0198057 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0198023 |
| RPL6 | ribosomal protein L6 | 0.0196342 |
| RASA2 | RAS p21 protein activator 2 | 0.0195693 |
| POM121 | POM121 transmembrane nucleoporin | 0.0195513 |
| CAB39 | calcium binding protein 39 | 0.019547 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0194962 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0194702 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0194691 |
| WBP11 | WW domain binding protein 11 | 0.0191963 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.139998 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110576 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109443 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0840237 |
| LOX | lysyl oxidase | -0.0753833 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0693481 |
| NDRG1 | N-myc downstream regulated 1 | -0.0677762 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0636401 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0632562 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0594961 |
| EGR1 | early growth response 1 | -0.0579695 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0569832 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0506644 |
| HMGA2 | high mobility group AT-hook 2 | -0.0504678 |
| HMGA1 | high mobility group AT-hook 1 | -0.0498824 |
| CDH13 | cadherin 13 | -0.0482533 |
| TMSB10 | thymosin beta 10 | -0.0466689 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0466596 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0423275 |
| PKM | pyruvate kinase, muscle | -0.0421561 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0418017 |
| NRG1 | neuregulin 1 | -0.0399412 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0396505 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0391194 |
| VEGFA | vascular endothelial growth factor A | -0.0385281 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0385097 |
| TGFB1 | transforming growth factor, beta 1 | -0.0376236 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0365871 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0345197 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0343375 |
| GLCCI1 | glucocorticoid induced 1 | -0.0342477 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.033852 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0326866 |
| MAP1B | microtubule-associated protein 1B | -0.0322348 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0321942 |
| AADAC | arylacetamide deacetylase | -0.0319425 |
| MYADM | myeloid-associated differentiation marker | -0.0307933 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0306137 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0292875 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0292295 |
| RPL35A | ribosomal protein L35a | -0.0288223 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0285192 |
| SYT1 | synaptotagmin I | -0.0283593 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0283333 |
| PRR16 | proline rich 16 | -0.0277504 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0275839 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0274797 |
| CALR | calreticulin | -0.0272509 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0259601 |
| YBX1 | Y box binding protein 1 | -0.0259363 |
| FBN1 | fibrillin 1 | -0.0254405 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0249259 |
| LDHA | lactate dehydrogenase A | -0.0247188 |
| POTEF | POTE ankyrin domain family, member F | -0.0246263 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0244518 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0241797 |
| NTN4 | netrin 4 | -0.0241482 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0240818 |
| PFN1 | profilin 1 | -0.0239549 |
| INTS6 | integrator complex subunit 6 | -0.0232604 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0232538 |
| TAPBP | TAP binding protein (tapasin) | -0.0228956 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0228846 |
| INSIG1 | insulin induced gene 1 | -0.0221067 |
| PRKCA | protein kinase C, alpha | -0.0220363 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0219798 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0218594 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0216145 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0215178 |
| ARF4 | ADP-ribosylation factor 4 | -0.0212139 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0211922 |
| VIM | vimentin | -0.0210808 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0208368 |
| CLIC4 | chloride intracellular channel 4 | -0.0207319 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0207236 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0205888 |
| S100A6 | S100 calcium binding protein A6 | -0.0205526 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0204819 |
| MTSS1 | metastasis suppressor 1 | -0.0202058 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0200774 |
| VRK2 | vaccinia related kinase 2 | -0.0200126 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0198177 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0197544 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0196503 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0196327 |
| RPLP1 | ribosomal protein, large, P1 | -0.0195195 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0184964 |
| MEF2A | myocyte enhancer factor 2A | -0.0184725 |
| VCL | vinculin | -0.0182764 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0181805 |
| RPL28 | ribosomal protein L28 | -0.0178784 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0178333 |
| CDK14 | cyclin-dependent kinase 14 | -0.0177654 |
| PLIN2 | perilipin 2 | -0.0176866 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0176747 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.017412 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.017321 |
| TAGLN2 | transgelin 2 | -0.0173147 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0171957 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0170486 |
