| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0554028 |
| PCBP2 | poly(rC) binding protein 2 | 0.0374671 |
| TPM3 | tropomyosin 3 | 0.0349204 |
| COPA | coatomer protein complex, subunit alpha | 0.0273852 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0265542 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0242778 |
| CCNL1 | cyclin L1 | 0.0240418 |
| RPL3 | ribosomal protein L3 | 0.0227452 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0225515 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0223541 |
| HDGF | hepatoma-derived growth factor | 0.0218868 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0217462 |
| H1-0 | H1.0 linker histone | 0.0209802 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0193279 |
| STC1 | stanniocalcin 1 | 0.0181316 |
| NOP58 | NOP58 ribonucleoprotein | 0.018067 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0180382 |
| MCL1 | myeloid cell leukemia 1 | 0.0180039 |
| SETD5 | SET domain containing 5 | 0.0167741 |
| SET | SET nuclear proto-oncogene | 0.0165695 |
| RPL4 | ribosomal protein L4 | 0.0164656 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0163625 |
| RPS2 | ribosomal protein S2 | 0.0162919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0162539 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0159918 |
| PUM2 | pumilio RNA-binding family member 2 | 0.015979 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0157682 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0155818 |
| TFG | TRK-fused gene | 0.0151734 |
| JMJD1C | jumonji domain containing 1C | 0.0146857 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0144746 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0139216 |
| JUN | jun proto-oncogene | 0.0137399 |
| WDR43 | WD repeat domain 43 | 0.0137159 |
| NOTCH2 | notch 2 | 0.0136071 |
| WASF2 | WAS protein family, member 2 | 0.0135278 |
| RPS7 | ribosomal protein S7 | 0.0134317 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.01341 |
| RAD51B | RAD51 paralog B | 0.0134081 |
| RBM39 | RNA binding motif protein 39 | 0.0133129 |
| HLA-A | major histocompatibility complex, class I, A | 0.0133093 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0128731 |
| EHBP1 | EH domain binding protein 1 | 0.0128634 |
| RPS12 | ribosomal protein S12 | 0.0127199 |
| GOLGA4 | golgin A4 | 0.0126178 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0125981 |
| HELZ | helicase with zinc finger | 0.0124197 |
| RBM26 | RNA binding motif protein 26 | 0.0124194 |
| ADAR | adenosine deaminase, RNA-specific | 0.0122774 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0122602 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.012181 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0118239 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0118001 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0116924 |
| MSN | moesin | 0.0115955 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0115016 |
| TLN1 | talin 1 | 0.0114028 |
| PLS3 | plastin 3 | 0.0113712 |
| NCKAP1 | NCK-associated protein 1 | 0.0113348 |
| SRP54 | signal recognition particle 54kDa | 0.0112855 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0112766 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0112397 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0112273 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0109476 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0109242 |
| VARS1 | valyl-tRNA synthetase 1 | 0.0108753 |
| TMEM39A | transmembrane protein 39A | 0.0107947 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0107885 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0107584 |
| PCBP1 | poly(rC) binding protein 1 | 0.0106994 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0106671 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0105959 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0104125 |
| SBF2 | SET binding factor 2 | 0.0104114 |
| CRY1 | cryptochrome circadian clock 1 | 0.010407 |
| KMT5B | lysine methyltransferase 5B | 0.0103851 |
| NBPF15 | neuroblastoma breakpoint family, member 15 | 0.010292 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0102253 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0101836 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0100628 |
| SEC24A | SEC24 family member A | 0.00998942 |
| RPS3 | ribosomal protein S3 | 0.00992572 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0099001 |
| RBM25 | RNA binding motif protein 25 | 0.00989209 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.00978557 |
| DIAPH1 | diaphanous-related formin 1 | 0.00978361 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.00974857 |
| VMP1 | vacuole membrane protein 1 | 0.00972408 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.00967303 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00961146 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.00960932 |
| MORF4L2 | mortality factor 4 like 2 | 0.00952609 |
| ZNF292 | zinc finger protein 292 | 0.0094175 |
| WDR35 | WD repeat domain 35 | 0.00940157 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00938502 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00933577 |
| DENND4A | DENN/MADD domain containing 4A | 0.00930843 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00918366 |
| MLF1 | myeloid leukemia factor 1 | 0.00913932 |
| PER1 | period circadian clock 1 | 0.00913887 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.105216 |
| TMSB10 | thymosin beta 10 | -0.0560527 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.047316 |
| RPL35A | ribosomal protein L35a | -0.0430521 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0412915 |
| RPS21 | ribosomal protein S21 | -0.0372299 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0351326 |
| RPLP1 | ribosomal protein, large, P1 | -0.0350558 |
| RPL38 | ribosomal protein L38 | -0.0318562 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0288187 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0261084 |
| RPLP0 | ribosomal protein, large, P0 | -0.02475 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0242547 |
| GRAMD1B | GRAM domain containing 1B | -0.0236568 |
| RPLP2 | ribosomal protein, large, P2 | -0.0236472 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0236439 |
| RPS15 | ribosomal protein S15 | -0.0234508 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.022949 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0228734 |
| RPS4X | ribosomal protein S4, X-linked | -0.0216128 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0214053 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0211467 |
| CAVIN1 | caveolae associated protein 1 | -0.0205445 |
| RPL31 | ribosomal protein L31 | -0.0203056 |
| RPS13 | ribosomal protein S13 | -0.0203006 |
| RPS24 | ribosomal protein S24 | -0.0202505 |
| RPS29 | ribosomal protein S29 | -0.0198819 |
| RPL26 | ribosomal protein L26 | -0.0192274 |
| RPL34 | ribosomal protein L34 | -0.0191708 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0191067 |
| RPL23 | ribosomal protein L23 | -0.0188911 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0184864 |
| RPL19 | ribosomal protein L19 | -0.0183844 |
| YBX3 | Y box binding protein 3 | -0.0183218 |
| RPL5 | ribosomal protein L5 | -0.0182792 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0176376 |
| EGR1 | early growth response 1 | -0.0175883 |
| MED13L | mediator complex subunit 13-like | -0.016664 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0165401 |
| RPS23 | ribosomal protein S23 | -0.0164332 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0164064 |
| RPL8 | ribosomal protein L8 | -0.0163468 |
| RPS10 | ribosomal protein S10 | -0.0163378 |
| MT2A | metallothionein 2A | -0.0162954 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0162349 |
| RPS8 | ribosomal protein S8 | -0.0161483 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0161033 |
| RAN | RAN, member RAS oncogene family | -0.016085 |
| WWOX | WW domain containing oxidoreductase | -0.0160184 |
| RRM2 | ribonucleotide reductase M2 | -0.015709 |
| IER3 | immediate early response 3 | -0.0154398 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0153605 |
| TXNRD1 | thioredoxin reductase 1 | -0.0152916 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0152891 |
| DEK | DEK proto-oncogene | -0.0151571 |
| PKM | pyruvate kinase, muscle | -0.0150514 |
| CCND1 | cyclin D1 | -0.0148605 |
| RPL36A | ribosomal protein L36a | -0.0147859 |
| FUS | FUS RNA binding protein | -0.0143372 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0140842 |
| RPL32 | ribosomal protein L32 | -0.014014 |
| RPS27A | ribosomal protein S27a | -0.013983 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0136829 |
| TPI1 | triosephosphate isomerase 1 | -0.0133822 |
| GLO1 | glyoxalase I | -0.0132997 |
| HLA-B | major histocompatibility complex, class I, B | -0.0131921 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0131646 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0130951 |
| RPL28 | ribosomal protein L28 | -0.0127958 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0125866 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0124533 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0124259 |
| TBCA | tubulin folding cofactor A | -0.0120997 |
| SMYD3 | SET and MYND domain containing 3 | -0.0120446 |
| RPL37 | ribosomal protein L37 | -0.0117522 |
| RPS16 | ribosomal protein S16 | -0.0117019 |
| S100A6 | S100 calcium binding protein A6 | -0.0116596 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.01136 |
| CDK12 | cyclin-dependent kinase 12 | -0.011219 |
| H3-3B | H3.3 histone B | -0.0111874 |
| AEBP2 | AE binding protein 2 | -0.0111564 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0111391 |
| DST | dystonin | -0.0111283 |
| UBB | ubiquitin B | -0.0107983 |
| ZNF217 | zinc finger protein 217 | -0.0107967 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.010642 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0105913 |
| RPS20 | ribosomal protein S20 | -0.0105699 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0104835 |
| KRT18 | keratin 18, type I | -0.0104807 |
| NF1 | neurofibromin 1 | -0.0104549 |
| SEPTIN7 | septin 7 | -0.0104486 |
| RPS19 | ribosomal protein S19 | -0.0104091 |
| AAK1 | AP2 associated kinase 1 | -0.0103883 |
| RPL11 | ribosomal protein L11 | -0.0103603 |
| XPO1 | exportin 1 | -0.0103388 |
| TUBB | tubulin, beta class I | -0.0102334 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | -0.0101314 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0101125 |
| HMGB1 | high mobility group box 1 | -0.0100381 |
