| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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96 genes differentially expressed following the Talc_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.195906 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.185307 |
| SLC38A1 | solute carrier family 38, member 1 | 0.183348 |
| FN1 | fibronectin 1 | 0.161146 |
| MT2A | metallothionein 2A | 0.152423 |
| UBC | ubiquitin C | 0.13303 |
| PTMA | prothymosin, alpha | 0.121493 |
| EGFR | epidermal growth factor receptor | 0.118796 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.10351 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.102475 |
| RAB1A | RAB1A, member RAS oncogene family | 0.101021 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0953955 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0829949 |
| PGK1 | phosphoglycerate kinase 1 | 0.080338 |
| NUP58 | nucleoporin 58 | 0.0767326 |
| FAM13A | family with sequence similarity 13, member A | 0.0763582 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0701318 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0695136 |
| ANXA2 | annexin A2 | 0.0683139 |
| VIM | vimentin | 0.0664849 |
| FTL | ferritin, light polypeptide | 0.0648035 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0642133 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.063729 |
| RLF | rearranged L-myc fusion | 0.0605285 |
| TMSB10 | thymosin beta 10 | 0.0568686 |
| SPAG9 | sperm associated antigen 9 | 0.0548108 |
| RTN4 | reticulon 4 | 0.0546362 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0532617 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0528865 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0524761 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0514437 |
| TXNRD1 | thioredoxin reductase 1 | 0.0492222 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0468365 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0466086 |
| RNF145 | ring finger protein 145 | 0.0360567 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.029213 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0265118 |
| GPC6 | glypican 6 | 0.0235881 |
| JMJD1C | jumonji domain containing 1C | 0.0224247 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0215686 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0180135 |
| GOLGA4 | golgin A4 | 0.016902 |
| COL1A1 | collagen, type I, alpha 1 | 0.0126283 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0110065 |
| CCNI | cyclin I | 0.00973472 |
| PARD3 | par-3 family cell polarity regulator | 0.0096355 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00366957 |
| RPL23 | ribosomal protein L23 | 0.00297219 |
| RPS27A | ribosomal protein S27a | 0.00110984 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.182506 |
| MYO1E | myosin IE | -0.157265 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.134551 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.110015 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.107615 |
| VMP1 | vacuole membrane protein 1 | -0.105328 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.103737 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0967863 |
| TPM4 | tropomyosin 4 | -0.0910455 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0907055 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.090294 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0868242 |
| PTK2 | protein tyrosine kinase 2 | -0.0818336 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0782003 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0758417 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0708602 |
| NDRG1 | N-myc downstream regulated 1 | -0.0669859 |
| LDHA | lactate dehydrogenase A | -0.0651729 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0649348 |
| ACTN4 | actinin, alpha 4 | -0.0631783 |
| RPS3 | ribosomal protein S3 | -0.0584892 |
| USP34 | ubiquitin specific peptidase 34 | -0.058034 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0579391 |
| LMO7 | LIM domain 7 | -0.0547073 |
| SNX9 | sorting nexin 9 | -0.0523772 |
| ITGA6 | integrin, alpha 6 | -0.0501244 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0501099 |
| CD44 | CD44 molecule (Indian blood group) | -0.0484809 |
| RPS6 | ribosomal protein S6 | -0.0457927 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0410552 |
| PKM | pyruvate kinase, muscle | -0.0395341 |
| MYO6 | myosin VI | -0.0364407 |
| DSPP | dentin sialophosphoprotein | -0.0361536 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0351146 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0272456 |
| PDE10A | phosphodiesterase 10A | -0.0240371 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0226776 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0198811 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0173671 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0163892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0162097 |
| PRRC2C | proline-rich coiled-coil 2C | -0.01374 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.00783359 |
| SYT1 | synaptotagmin I | -0.00751524 |
| DST | dystonin | -0.00380445 |
| ZNF292 | zinc finger protein 292 | -0.00338264 |
| SBF2 | SET binding factor 2 | -6.25805E-4 |
