| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NTM | neurotrimin | 0.0825388 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0765336 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0581893 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0570965 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0512653 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0506373 |
| PCDH9 | protocadherin 9 | 0.0500649 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0488173 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0465391 |
| CADM2 | cell adhesion molecule 2 | 0.0445253 |
| FTL | ferritin, light polypeptide | 0.0384064 |
| PLPP1 | phospholipid phosphatase 1 | 0.0379453 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0370022 |
| RPL37A | ribosomal protein L37a | 0.0347924 |
| NEBL | nebulette | 0.0345847 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0342206 |
| NHSL1 | NHS-like 1 | 0.0329629 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0327004 |
| STMN1 | stathmin 1 | 0.0325261 |
| B2M | beta-2-microglobulin | 0.0315179 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0310228 |
| PTMA | prothymosin, alpha | 0.0299511 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0295324 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0294721 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268602 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0254166 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0252426 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0249373 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0243669 |
| RPS12 | ribosomal protein S12 | 0.0242288 |
| ZFP36 | ZFP36 ring finger protein | 0.0238742 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0235642 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.023534 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.0234011 |
| TPM3 | tropomyosin 3 | 0.0226908 |
| RPL18 | ribosomal protein L18 | 0.0225463 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0224119 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0217156 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0216826 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0215949 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0215645 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0214865 |
| FAM13A | family with sequence similarity 13, member A | 0.021118 |
| ATP13A3 | ATPase type 13A3 | 0.0210603 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0210325 |
| MT2A | metallothionein 2A | 0.0209784 |
| RUNX1 | runt-related transcription factor 1 | 0.020877 |
| TNS3 | tensin 3 | 0.0207387 |
| RAD51B | RAD51 paralog B | 0.0206972 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0206734 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0205999 |
| RPL3 | ribosomal protein L3 | 0.0205128 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0205042 |
| NRG1 | neuregulin 1 | 0.020487 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0203832 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0203346 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0201237 |
| GPX4 | glutathione peroxidase 4 | 0.0201115 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0200344 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0199595 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0199092 |
| ASPH | aspartate beta-hydroxylase | 0.0199008 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0198049 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.019712 |
| MYO10 | myosin X | 0.0196967 |
| FOXG1 | forkhead box G1 | 0.0196736 |
| RPS2 | ribosomal protein S2 | 0.019634 |
| STC1 | stanniocalcin 1 | 0.0193809 |
| FILIP1 | filamin A interacting protein 1 | 0.0193681 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0191002 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0189158 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0188867 |
| LRRC4C | leucine rich repeat containing 4C | 0.0187283 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0186126 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.0186036 |
| HMCN1 | hemicentin 1 | 0.0183812 |
| PRELID2 | PRELI domain containing 2 | 0.0180828 |
| CD44 | CD44 molecule (Indian blood group) | 0.0180624 |
| RPLP2 | ribosomal protein, large, P2 | 0.0179927 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0179684 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0174001 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0172513 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0172341 |
| SQSTM1 | sequestosome 1 | 0.0171287 |
| GSE1 | Gse1 coiled-coil protein | 0.0170729 |
| USP53 | ubiquitin specific peptidase 53 | 0.0170596 |
| S100A10 | S100 calcium binding protein A10 | 0.0167231 |
| SCFD1 | sec1 family domain containing 1 | 0.0165945 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0164833 |
| VARS1 | valyl-tRNA synthetase 1 | 0.0164622 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.016432 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0163403 |
| ENO1 | enolase 1, (alpha) | 0.0163334 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0160627 |
| RPS19 | ribosomal protein S19 | 0.0160612 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0158025 |
| PHIP | pleckstrin homology domain interacting protein | 0.0156729 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0156648 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0156575 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 0.0154384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.113548 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0851463 |
| FOXP2 | forkhead box P2 | -0.0833493 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0786726 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0767939 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0699388 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0675544 |
| PEG10 | paternally expressed 10 | -0.0668815 |
| ENAH | enabled homolog (Drosophila) | -0.0665087 |
| ZNF292 | zinc finger protein 292 | -0.0603411 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0565382 |
| PDGFC | platelet derived growth factor C | -0.052798 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0517628 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0511185 |
| MEIS2 | Meis homeobox 2 | -0.0508611 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0498493 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0497389 |
| MTF2 | metal response element binding transcription factor 2 | -0.0492612 |
| RBM39 | RNA binding motif protein 39 | -0.0488227 |
| TENM3 | teneurin transmembrane protein 3 | -0.0484912 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0476889 |
| EVI5 | ecotropic viral integration site 5 | -0.0451302 |
| RLF | rearranged L-myc fusion | -0.0438472 |
| DST | dystonin | -0.0426989 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0419771 |
| FBXO11 | F-box protein 11 | -0.0402862 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0402028 |
| WDR43 | WD repeat domain 43 | -0.0400811 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0395703 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0388245 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0379676 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.037604 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0375891 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0374165 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0365932 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0353611 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0352537 |
| HMGA2 | high mobility group AT-hook 2 | -0.0351856 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0349593 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0347179 |
| THBS1 | thrombospondin 1 | -0.0345085 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0337776 |
| PTK2 | protein tyrosine kinase 2 | -0.0337338 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0335516 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0334875 |
| COL3A1 | collagen, type III, alpha 1 | -0.0331014 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0330117 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0329563 |
| RHEB | Ras homolog enriched in brain | -0.032653 |
| MEMO1 | mediator of cell motility 1 | -0.0324706 |
| HMGB2 | high mobility group box 2 | -0.0323614 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0321622 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0317111 |
| CRY1 | cryptochrome circadian clock 1 | -0.0315572 |
| SIK3 | SIK family kinase 3 | -0.0309221 |
| TMSB4X | thymosin beta 4, X-linked | -0.0308824 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0308127 |
| CLTC | clathrin, heavy chain (Hc) | -0.0305486 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0305126 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0304124 |
| RPS16 | ribosomal protein S16 | -0.0303902 |
| PRTG | protogenin | -0.0300859 |
| OGA | O-GlcNAcase | -0.0300311 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0292433 |
| OLA1 | Obg-like ATPase 1 | -0.0281553 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0279445 |
| MATR3 | matrin 3 | -0.027808 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0277629 |
| SHROOM3 | shroom family member 3 | -0.0277579 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0274504 |
| TLK2 | tousled-like kinase 2 | -0.0271553 |
| ZNF385D | zinc finger protein 385D | -0.0271214 |
| SRP72 | signal recognition particle 72kDa | -0.0270074 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0267082 |
| SP3 | Sp3 transcription factor | -0.0267006 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0265709 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0265435 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0261061 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0259767 |
| TXNRD1 | thioredoxin reductase 1 | -0.0259098 |
| RYBP | RING1 and YY1 binding protein | -0.0257659 |
| METAP2 | methionyl aminopeptidase 2 | -0.0255747 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0254627 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0252039 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0251463 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0246667 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0245976 |
| COG5 | component of oligomeric golgi complex 5 | -0.0243134 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0241397 |
| NUP155 | nucleoporin 155kDa | -0.0241357 |
| SRP54 | signal recognition particle 54kDa | -0.0240157 |
| CUL3 | cullin 3 | -0.0239972 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0237482 |
| ARF1 | ADP-ribosylation factor 1 | -0.0236861 |
| DSTN | destrin (actin depolymerizing factor) | -0.0236717 |
| CENPE | centromere protein E, 312kDa | -0.0233827 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0232989 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0232681 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0232119 |
| NOP58 | NOP58 ribonucleoprotein | -0.0230881 |
