| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0867944 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0838847 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0752442 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.064407 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0464016 |
| CCNL1 | cyclin L1 | 0.0460613 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0458509 |
| MSN | moesin | 0.0452808 |
| NAV2 | neuron navigator 2 | 0.0433077 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0426627 |
| RPS2 | ribosomal protein S2 | 0.0422124 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.040665 |
| ZNF292 | zinc finger protein 292 | 0.0388676 |
| CENPF | centromere protein F, 350/400kDa | 0.0384471 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0384212 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0383592 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0380333 |
| RPL4 | ribosomal protein L4 | 0.0376265 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0372908 |
| QKI | QKI, KH domain containing, RNA binding | 0.0367309 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0358573 |
| PCBP2 | poly(rC) binding protein 2 | 0.0353986 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0353679 |
| ATP13A3 | ATPase type 13A3 | 0.0348121 |
| FRMD4A | FERM domain containing 4A | 0.0340485 |
| PTMA | prothymosin, alpha | 0.0324441 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0311994 |
| RPL3 | ribosomal protein L3 | 0.028365 |
| RPS12 | ribosomal protein S12 | 0.0278558 |
| DST | dystonin | 0.0270805 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0270657 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0270523 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0269132 |
| NAV1 | neuron navigator 1 | 0.0267334 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0262762 |
| MKI67 | marker of proliferation Ki-67 | 0.0256958 |
| STC1 | stanniocalcin 1 | 0.0254694 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0252378 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0250654 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0246808 |
| AFDN | afadin, adherens junction formation factor | 0.0245063 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0244606 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0241029 |
| VCL | vinculin | 0.0236654 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0234171 |
| NEK7 | NIMA-related kinase 7 | 0.0231444 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0229793 |
| PDE10A | phosphodiesterase 10A | 0.022525 |
| TPM3 | tropomyosin 3 | 0.0222648 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0219342 |
| FNIP1 | folliculin interacting protein 1 | 0.0219272 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.021805 |
| H1-4 | H1.4 linker histone, cluster member | 0.021656 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0215702 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0210657 |
| HLA-A | major histocompatibility complex, class I, A | 0.0209465 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0209063 |
| CNN3 | calponin 3, acidic | 0.0207881 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.020432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.020297 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0202064 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0199932 |
| KIF4A | kinesin family member 4A | 0.0199683 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0197684 |
| NUP58 | nucleoporin 58 | 0.0196031 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0195785 |
| CALD1 | caldesmon 1 | 0.0195561 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0190688 |
| CREBRF | CREB3 regulatory factor | 0.0187696 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0187401 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0187152 |
| TMEM263 | transmembrane protein 263 | 0.0186908 |
| RNF145 | ring finger protein 145 | 0.0184577 |
| PRR16 | proline rich 16 | 0.0184257 |
| SYAP1 | synapse associated protein 1 | 0.0183394 |
| WAC | WW domain containing adaptor with coiled-coil | 0.018274 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.01819 |
| RPS3 | ribosomal protein S3 | 0.0181345 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.017883 |
| ANLN | anillin, actin binding protein | 0.0176561 |
| ITSN2 | intersectin 2 | 0.0176088 |
| CDK6 | cyclin-dependent kinase 6 | 0.017368 |
| FAM13A | family with sequence similarity 13, member A | 0.0173645 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0173234 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0172778 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0172099 |
| ENO1 | enolase 1, (alpha) | 0.0171128 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0169464 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0168798 |
| PGM3 | phosphoglucomutase 3 | 0.0166163 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0161441 |
| SMAP1 | small ArfGAP 1 | 0.0161245 |
| FOSL1 | FOS-like antigen 1 | 0.0161022 |
| CRY1 | cryptochrome circadian clock 1 | 0.0160872 |
| KYNU | kynureninase | 0.0160368 |
| HLA-G | major histocompatibility complex, class I, G | 0.0160291 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0159279 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0158679 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0158018 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0156764 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.177319 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.149579 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141549 |
| VIM | vimentin | -0.128338 |
| HLA-B | major histocompatibility complex, class I, B | -0.117018 |
| RPS24 | ribosomal protein S24 | -0.0861138 |
| IER3 | immediate early response 3 | -0.085694 |
| NDRG1 | N-myc downstream regulated 1 | -0.0846166 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0820694 |
| TMSB10 | thymosin beta 10 | -0.0807745 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0713836 |
| TXNIP | thioredoxin interacting protein | -0.0699156 |
| RPL35A | ribosomal protein L35a | -0.0678714 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0629625 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0628272 |
| SMAD3 | SMAD family member 3 | -0.0621547 |
| VEGFA | vascular endothelial growth factor A | -0.0588068 |
| RPS4X | ribosomal protein S4, X-linked | -0.0584951 |
| CTSD | cathepsin D | -0.0568604 |
| SDC4 | syndecan 4 | -0.0562066 |
| FTL | ferritin, light polypeptide | -0.0545826 |
| RPL38 | ribosomal protein L38 | -0.0539685 |
| RPL23 | ribosomal protein L23 | -0.0517149 |
| RPLP1 | ribosomal protein, large, P1 | -0.0506771 |
| RPL27A | ribosomal protein L27a | -0.0484896 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484002 |
| SFTPA2 | surfactant protein A2 | -0.0477859 |
| RPS21 | ribosomal protein S21 | -0.0476693 |
| CALR | calreticulin | -0.0468705 |
| RPS13 | ribosomal protein S13 | -0.0423531 |
| RPL36A | ribosomal protein L36a | -0.0410479 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0409203 |
| CTSB | cathepsin B | -0.0405809 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0404048 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0402076 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0401942 |
| UBC | ubiquitin C | -0.0398366 |
| RPL11 | ribosomal protein L11 | -0.0395434 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0394572 |
| RPLP2 | ribosomal protein, large, P2 | -0.0394077 |
| RPL39 | ribosomal protein L39 | -0.0391648 |
| RPS20 | ribosomal protein S20 | -0.0387765 |
| TAPBP | TAP binding protein (tapasin) | -0.0379054 |
| ADM | adrenomedullin | -0.0379052 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0371955 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0370747 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0352381 |
| PHIP | pleckstrin homology domain interacting protein | -0.0350966 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0348151 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0347127 |
| RPL28 | ribosomal protein L28 | -0.0345218 |
| CANX | calnexin | -0.0333549 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0333244 |
| HLA-E | major histocompatibility complex, class I, E | -0.0331239 |
| LOXL2 | lysyl oxidase-like 2 | -0.0328737 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0326197 |
| TUBB | tubulin, beta class I | -0.032543 |
| RPL32 | ribosomal protein L32 | -0.0318484 |
| BPTF | bromodomain PHD finger transcription factor | -0.0317838 |
| COL1A2 | collagen, type I, alpha 2 | -0.0311804 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0310085 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0308218 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0306898 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0304322 |
| CD44 | CD44 molecule (Indian blood group) | -0.0296309 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.029616 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0295606 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0292239 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0291947 |
| LDHA | lactate dehydrogenase A | -0.0289674 |
| DEK | DEK proto-oncogene | -0.0288191 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0287247 |
| BICC1 | BicC family RNA binding protein 1 | -0.0285399 |
| OGA | O-GlcNAcase | -0.0281959 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0281061 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0278945 |
| ZNF207 | zinc finger protein 207 | -0.0278144 |
| WDR45B | WD repeat domain 45B | -0.0277925 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0275315 |
| RPL8 | ribosomal protein L8 | -0.027103 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0267192 |
| SPAG9 | sperm associated antigen 9 | -0.0267 |
| TXNRD1 | thioredoxin reductase 1 | -0.0265944 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0264668 |
| GLIS3 | GLIS family zinc finger 3 | -0.0263364 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0262224 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0258528 |
| RPLP0 | ribosomal protein, large, P0 | -0.0257824 |
| RPS27A | ribosomal protein S27a | -0.0255324 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0254248 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0251516 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0251072 |
| NGLY1 | N-glycanase 1 | -0.0249423 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.024863 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0246766 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0243894 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0241608 |
| ATXN1 | ataxin 1 | -0.0240525 |
| ARF1 | ADP-ribosylation factor 1 | -0.0240233 |
| RPL37 | ribosomal protein L37 | -0.0239354 |
