| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.140183 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.117724 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0706001 |
| IL6 | interleukin 6 | 0.0699791 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0698904 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0679697 |
| B2M | beta-2-microglobulin | 0.0656795 |
| PRELID2 | PRELI domain containing 2 | 0.0603878 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0596289 |
| EFNA5 | ephrin-A5 | 0.0584305 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0555007 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0553787 |
| KYNU | kynureninase | 0.0529721 |
| CAVIN1 | caveolae associated protein 1 | 0.0495306 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0487834 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0459316 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0453489 |
| FMNL2 | formin-like 2 | 0.0451594 |
| TMEM165 | transmembrane protein 165 | 0.0446858 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0446268 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0430173 |
| OXSR1 | oxidative stress responsive 1 | 0.0416637 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0408217 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0395227 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0390008 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0385605 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0378934 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.037766 |
| DCN | decorin | 0.0375209 |
| RAI14 | retinoic acid induced 14 | 0.0371619 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0367839 |
| RPL26 | ribosomal protein L26 | 0.0363499 |
| ETV6 | ets variant 6 | 0.0362122 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0357433 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0350708 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0346919 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0345908 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0339362 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0333212 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0331941 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0330963 |
| TMF1 | TATA element modulatory factor 1 | 0.0329389 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0325078 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0322777 |
| STK17A | serine/threonine kinase 17a | 0.0317216 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0314644 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0314485 |
| GLIS3 | GLIS family zinc finger 3 | 0.0313017 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0300498 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0297821 |
| FAM13A | family with sequence similarity 13, member A | 0.0297768 |
| SERINC3 | serine incorporator 3 | 0.029493 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.029236 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0291445 |
| TNS3 | tensin 3 | 0.0291125 |
| STC1 | stanniocalcin 1 | 0.0290993 |
| KAZN | kazrin, periplakin interacting protein | 0.0290755 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0290035 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.029003 |
| IGF2 | insulin-like growth factor 2 | 0.028967 |
| HLA-A | major histocompatibility complex, class I, A | 0.028939 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0289071 |
| STX12 | syntaxin 12 | 0.0288904 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0288132 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0286366 |
| PALLD | palladin, cytoskeletal associated protein | 0.0285931 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0284409 |
| NKTR | natural killer cell triggering receptor | 0.0283985 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0283085 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0282625 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.028216 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0280942 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0280315 |
| RPS5 | ribosomal protein S5 | 0.0279284 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0276418 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0273024 |
| GSDME | gasdermin E | 0.0272177 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0271977 |
| SP100 | SP100 nuclear antigen | 0.0271684 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.027014 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0268816 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 0.0268157 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0267066 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | 0.0266324 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.026565 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0265021 |
| HMBOX1 | homeobox containing 1 | 0.0262665 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0260982 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0259684 |
| ATG14 | autophagy related 14 | 0.0258281 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0256393 |
| JAK1 | Janus kinase 1 | 0.0255852 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0255196 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0253938 |
| PRKD3 | protein kinase D3 | 0.0251623 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.02502 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0249514 |
| PTGES2 | prostaglandin E synthase 2 | 0.0248814 |
| KIF4A | kinesin family member 4A | 0.0247682 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0247183 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.223151 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.194839 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.17618 |
| NDRG1 | N-myc downstream regulated 1 | -0.123297 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.106492 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0990723 |
| MEF2A | myocyte enhancer factor 2A | -0.0861085 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0836984 |
| FN1 | fibronectin 1 | -0.0770337 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0672128 |
| LOX | lysyl oxidase | -0.0664826 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0619754 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0576856 |
| POTEF | POTE ankyrin domain family, member F | -0.0570646 |
| COL1A2 | collagen, type I, alpha 2 | -0.0563435 |
| ZNF395 | zinc finger protein 395 | -0.0552843 |
| COL6A1 | collagen, type VI, alpha 1 | -0.052558 |
| RTN4 | reticulon 4 | -0.0524475 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0501294 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.049844 |
| ZNF292 | zinc finger protein 292 | -0.0485567 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0469123 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0467388 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0465554 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0453479 |
| VEGFA | vascular endothelial growth factor A | -0.0449318 |
| CALR | calreticulin | -0.0446547 |
| PKM | pyruvate kinase, muscle | -0.0446312 |
| EGR1 | early growth response 1 | -0.0440023 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0423682 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.040352 |
| TPM1 | tropomyosin 1 (alpha) | -0.0396348 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0395117 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0392784 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0385247 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0380315 |
| ENO1 | enolase 1, (alpha) | -0.0379923 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0370672 |
| ANXA2 | annexin A2 | -0.0364254 |
| CRLS1 | cardiolipin synthase 1 | -0.0359035 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0357556 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0346099 |
| SETD5 | SET domain containing 5 | -0.0344277 |
| LDHA | lactate dehydrogenase A | -0.0344081 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0329218 |
| CADM1 | cell adhesion molecule 1 | -0.0328485 |
| RPL28 | ribosomal protein L28 | -0.0328096 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0327735 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0326644 |
| CCNL1 | cyclin L1 | -0.0326527 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0322938 |
| MORF4L2 | mortality factor 4 like 2 | -0.0320129 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0316845 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0316641 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.031334 |
| TNNC1 | troponin C type 1 (slow) | -0.0310942 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0306404 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0304699 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0303944 |
| CLIC4 | chloride intracellular channel 4 | -0.0293724 |
| TMEM123 | transmembrane protein 123 | -0.0292299 |
| MAP1B | microtubule-associated protein 1B | -0.0290726 |
| TMSB10 | thymosin beta 10 | -0.0289128 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0287835 |
| TNPO1 | transportin 1 | -0.0285981 |
| SYNPO | synaptopodin | -0.0285637 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0284278 |
| SPAG9 | sperm associated antigen 9 | -0.0280685 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0278716 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | -0.027574 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.027388 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0272666 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0270128 |
| CDK7 | cyclin-dependent kinase 7 | -0.0269942 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0269776 |
| CCDC47 | coiled-coil domain containing 47 | -0.0268271 |
| FRMD6 | FERM domain containing 6 | -0.0262767 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0262139 |
| FAM162A | family with sequence similarity 162, member A | -0.0262081 |
| CDK6 | cyclin-dependent kinase 6 | -0.0261866 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0261454 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0259224 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0258305 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0254986 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0254446 |
| PGK1 | phosphoglycerate kinase 1 | -0.0254403 |
| AAK1 | AP2 associated kinase 1 | -0.0253365 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0253183 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0252089 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.025177 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.025092 |
| HDLBP | high density lipoprotein binding protein | -0.0249753 |
| UBN1 | ubinuclein 1 | -0.0249612 |
| ITM2B | integral membrane protein 2B | -0.0249216 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0248137 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0247636 |
| MORF4L1 | mortality factor 4 like 1 | -0.0245322 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0245305 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0244378 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.0244097 |
