| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| YBX3 | Y box binding protein 3 | 0.0763934 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0733806 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0671037 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0610272 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0570993 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0485915 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0471606 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0468889 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.045837 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.045188 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0451663 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0451406 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0438388 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0428639 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0425495 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.04048 |
| RPS3 | ribosomal protein S3 | 0.0402992 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0380125 |
| MYO9A | myosin IXA | 0.0361395 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0339703 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0326407 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0321742 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0302449 |
| CALU | calumenin | 0.0293673 |
| KIAA1958 | KIAA1958 | 0.0290704 |
| RTN4 | reticulon 4 | 0.0289548 |
| PCBP2 | poly(rC) binding protein 2 | 0.0281036 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0279092 |
| ATP11B | ATPase, class VI, type 11B | 0.027488 |
| DST | dystonin | 0.0274179 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0272169 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0271878 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0259224 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.02554 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0247856 |
| H1-0 | H1.0 linker histone | 0.0247086 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0245529 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0245132 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0241497 |
| PHIP | pleckstrin homology domain interacting protein | 0.0239545 |
| CDK6 | cyclin-dependent kinase 6 | 0.0238981 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0237724 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0235463 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0230962 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0227009 |
| RBM27 | RNA binding motif protein 27 | 0.0226544 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0225921 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0222446 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0221569 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0220142 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0217798 |
| EXOC6B | exocyst complex component 6B | 0.0217554 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0217383 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0215831 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0215095 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0212648 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0211845 |
| ATP13A3 | ATPase type 13A3 | 0.0211709 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0211286 |
| CCNL1 | cyclin L1 | 0.0210963 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0210186 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0209053 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0208506 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0208274 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0204559 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0203832 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0202896 |
| HMG20A | high mobility group 20A | 0.0200774 |
| CCNT2 | cyclin T2 | 0.0200571 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0200416 |
| TTBK2 | tau tubulin kinase 2 | 0.0199309 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0199218 |
| ACTG1 | actin gamma 1 | 0.019897 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.0198795 |
| TRIM38 | tripartite motif containing 38 | 0.0198765 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0198713 |
| MED13L | mediator complex subunit 13-like | 0.019814 |
| ZNF292 | zinc finger protein 292 | 0.019804 |
| NPTN | neuroplastin | 0.0197367 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0196813 |
| RPN2 | ribophorin II | 0.0195442 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0194698 |
| PRKCE | protein kinase C, epsilon | 0.0193255 |
| CLINT1 | clathrin interactor 1 | 0.0192693 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0192114 |
| MCM8 | minichromosome maintenance complex component 8 | 0.0191759 |
| NPAT | nuclear protein, ataxia-telangiectasia locus | 0.0191027 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0189774 |
| MTMR14 | myotubularin related protein 14 | 0.0189605 |
| TPR | translocated promoter region, nuclear basket protein | 0.0186853 |
| POT1 | protection of telomeres 1 | 0.0185238 |
| CDC5L | cell division cycle 5-like | 0.018468 |
| LDLR | low density lipoprotein receptor | 0.0184336 |
| TXNRD1 | thioredoxin reductase 1 | 0.0183762 |
| SH3GL3 | SH3-domain GRB2-like 3 | 0.0183663 |
| CASP8AP2 | caspase 8 associated protein 2 | 0.0183621 |
| RUNX1 | runt-related transcription factor 1 | 0.0183593 |
| ZNF652 | zinc finger protein 652 | 0.0182499 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0179847 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.017965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0859421 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0789077 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0559196 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0520966 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.048919 |
| PKM | pyruvate kinase, muscle | -0.0463506 |
| FTL | ferritin, light polypeptide | -0.0456885 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0431249 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0414351 |
| TMSB10 | thymosin beta 10 | -0.0401614 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0393517 |
| RPS13 | ribosomal protein S13 | -0.0386028 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0385862 |
| RAB1A | RAB1A, member RAS oncogene family | -0.036773 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.034689 |
| RPL35A | ribosomal protein L35a | -0.0339231 |
| NAV2 | neuron navigator 2 | -0.0332105 |
| RNF213 | ring finger protein 213 | -0.0324844 |
| VIM | vimentin | -0.0318328 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0310842 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0310806 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0309456 |
| TAOK3 | TAO kinase 3 | -0.0306844 |
| RPS29 | ribosomal protein S29 | -0.0306639 |
| HMGA2 | high mobility group AT-hook 2 | -0.0302643 |
| RAI14 | retinoic acid induced 14 | -0.0301 |
| CCNH | cyclin H | -0.0298162 |
| IER3 | immediate early response 3 | -0.0293057 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0292501 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0284099 |
| PRKCA | protein kinase C, alpha | -0.0282258 |
| RPL37A | ribosomal protein L37a | -0.0278407 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0276919 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0275724 |
| RPS27A | ribosomal protein S27a | -0.0274819 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | -0.0273512 |
| INTS6 | integrator complex subunit 6 | -0.0273034 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0268905 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0267748 |
| SDCBP | syndecan binding protein (syntenin) | -0.0263735 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | -0.0256977 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0256587 |
| MYO9B | myosin IXB | -0.0256265 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.025593 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0252238 |
| FRMD6 | FERM domain containing 6 | -0.0251225 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0249924 |
| MATR3 | matrin 3 | -0.0247624 |
| RPL38 | ribosomal protein L38 | -0.0247383 |
| PODXL | podocalyxin-like | -0.0242296 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.0239358 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0238489 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0238063 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0234288 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.023274 |
| RPL7A | ribosomal protein L7a | -0.0230534 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0228125 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0228005 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0226642 |
| CCND1 | cyclin D1 | -0.0226045 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0225058 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0224295 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.022338 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0220943 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0218017 |
| RPS11 | ribosomal protein S11 | -0.0216093 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0210483 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0207322 |
| GPC5 | glypican 5 | -0.020688 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0204768 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0203736 |
| RPL19 | ribosomal protein L19 | -0.0203454 |
| LOC112694756 | uncharaterized LOC112694756 | -0.02021 |
| TAOK1 | TAO kinase 1 | -0.0200631 |
| CREBBP | CREB binding protein | -0.0199687 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0199356 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0199354 |
| ASPH | aspartate beta-hydroxylase | -0.0198227 |
| B2M | beta-2-microglobulin | -0.0197751 |
| CDC42SE2 | CDC42 small effector 2 | -0.0194834 |
| USP36 | ubiquitin specific peptidase 36 | -0.0194488 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0194077 |
| RNF145 | ring finger protein 145 | -0.0192778 |
| ZNF609 | zinc finger protein 609 | -0.0192569 |
| PRSS23 | protease, serine, 23 | -0.0191993 |
| RPL31 | ribosomal protein L31 | -0.0191697 |
| TBCA | tubulin folding cofactor A | -0.0191525 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0189384 |
| S100A9 | S100 calcium binding protein A9 | -0.018913 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0188498 |
| AAGAB | alpha- and gamma-adaptin binding protein | -0.0186666 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 | -0.0185496 |
| FERMT2 | fermitin family member 2 | -0.0183862 |
| FBXO11 | F-box protein 11 | -0.0183669 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0182529 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0181748 |
| FRYL | FRY-like | -0.0181582 |
| ATG7 | autophagy related 7 | -0.0181245 |
| PCNX2 | pecanex 2 | -0.018078 |
| TPX2 | TPX2, microtubule-associated | -0.0180474 |
