| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Talc perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Talc_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.189911 |
| GOLGA4 | golgin A4 | 0.063917 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0600663 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0550836 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0529945 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0519812 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0516549 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0499236 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0447258 |
| TPR | translocated promoter region, nuclear basket protein | 0.0426963 |
| CDC73 | cell division cycle 73 | 0.0422267 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0420875 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0414798 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0409812 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0390682 |
| COG5 | component of oligomeric golgi complex 5 | 0.0390664 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0381844 |
| ETNK1 | ethanolamine kinase 1 | 0.0378019 |
| RNF145 | ring finger protein 145 | 0.0375872 |
| OGA | O-GlcNAcase | 0.0373565 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0369107 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0368608 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0364243 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0353832 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0348523 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0343821 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0342308 |
| SUCO | SUN domain containing ossification factor | 0.0338475 |
| PCBP2 | poly(rC) binding protein 2 | 0.0335807 |
| FAM13A | family with sequence similarity 13, member A | 0.0333323 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0326342 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0323379 |
| CEP350 | centrosomal protein 350kDa | 0.0322637 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0319968 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0307872 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0305886 |
| TMF1 | TATA element modulatory factor 1 | 0.0303283 |
| COPA | coatomer protein complex, subunit alpha | 0.0303105 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0300088 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.029783 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0297165 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0288371 |
| NEK7 | NIMA-related kinase 7 | 0.0287117 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0283786 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0283618 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0282482 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0276275 |
| CLINT1 | clathrin interactor 1 | 0.0276186 |
| RBM25 | RNA binding motif protein 25 | 0.027434 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0273506 |
| RUNX2 | runt-related transcription factor 2 | 0.0273292 |
| CAB39 | calcium binding protein 39 | 0.0271758 |
| ZNF292 | zinc finger protein 292 | 0.0269214 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0269108 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0266243 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0265658 |
| HELZ | helicase with zinc finger | 0.026439 |
| SRP54 | signal recognition particle 54kDa | 0.0262572 |
| HDLBP | high density lipoprotein binding protein | 0.0260586 |
| CD44 | CD44 molecule (Indian blood group) | 0.0255771 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0255671 |
| RNF24 | ring finger protein 24 | 0.0255087 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0253368 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0253071 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0252758 |
| SIK3 | SIK family kinase 3 | 0.0252586 |
| ZFR | zinc finger RNA binding protein | 0.0250647 |
| CENPF | centromere protein F, 350/400kDa | 0.0250182 |
| YME1L1 | YME1-like 1 ATPase | 0.0245167 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.024234 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0239871 |
| RPS2 | ribosomal protein S2 | 0.0237987 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0234955 |
| FOXO3 | forkhead box O3 | 0.0234424 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0230627 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0228615 |
| AHR | aryl hydrocarbon receptor | 0.0227469 |
| CLTC | clathrin, heavy chain (Hc) | 0.0227184 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0226082 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0225352 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0224441 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0224179 |
| SEC24A | SEC24 family member A | 0.0220661 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0219917 |
| WDR26 | WD repeat domain 26 | 0.0219554 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0218013 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0210794 |
| CUL3 | cullin 3 | 0.0207949 |
| AFDN | afadin, adherens junction formation factor | 0.02079 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0206107 |
| KSR1 | kinase suppressor of ras 1 | 0.0205983 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0203062 |
| TMEM39A | transmembrane protein 39A | 0.0201659 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0200905 |
| SNX13 | sorting nexin 13 | 0.0198277 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0198055 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0197926 |
| RO60 | Ro60, Y RNA binding protein | 0.0197404 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0195555 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0195422 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.253026 |
| FN1 | fibronectin 1 | -0.197877 |
| HMGA2 | high mobility group AT-hook 2 | -0.134139 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.132663 |
| ASPH | aspartate beta-hydroxylase | -0.120909 |
| TMSB10 | thymosin beta 10 | -0.0868129 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0797069 |
| HLA-B | major histocompatibility complex, class I, B | -0.0791393 |
| STC2 | stanniocalcin 2 | -0.0764691 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0682374 |
| PTMA | prothymosin, alpha | -0.06614 |
| ITGA1 | integrin, alpha 1 | -0.0648369 |
| SQSTM1 | sequestosome 1 | -0.0614307 |
| TMSB4X | thymosin beta 4, X-linked | -0.0611676 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0596778 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0573425 |
| RAI14 | retinoic acid induced 14 | -0.0563182 |
| SYT1 | synaptotagmin I | -0.0557422 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.050873 |
| S100A6 | S100 calcium binding protein A6 | -0.0503939 |
| TMEM156 | transmembrane protein 156 | -0.0502242 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0502017 |
| FTL | ferritin, light polypeptide | -0.0500956 |
| PKM | pyruvate kinase, muscle | -0.0496539 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0494028 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0491801 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0481919 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0447086 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0426574 |
| IER3 | immediate early response 3 | -0.0421665 |
| ACTG1 | actin gamma 1 | -0.0418898 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0413301 |
| AEBP2 | AE binding protein 2 | -0.0400627 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0393863 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.039369 |
| INTS6 | integrator complex subunit 6 | -0.0391426 |
| B2M | beta-2-microglobulin | -0.0390193 |
| GLIS3 | GLIS family zinc finger 3 | -0.0387808 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0374734 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0360581 |
| EGR1 | early growth response 1 | -0.035043 |
| VIM | vimentin | -0.0336502 |
| VCL | vinculin | -0.0329216 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0323359 |
| CTSD | cathepsin D | -0.0320973 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0320044 |
| RPL31 | ribosomal protein L31 | -0.0314982 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0309014 |
| RPL38 | ribosomal protein L38 | -0.0307115 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0307033 |
| HMGA1 | high mobility group AT-hook 1 | -0.0306345 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0304145 |
| SFTPA2 | surfactant protein A2 | -0.0302582 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0296784 |
| ETV1 | ets variant 1 | -0.0291066 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0285294 |
| S100A10 | S100 calcium binding protein A10 | -0.0283091 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0280176 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0279974 |
| PALLD | palladin, cytoskeletal associated protein | -0.0278046 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0275238 |
| KLHL5 | kelch-like family member 5 | -0.0273943 |
| BPTF | bromodomain PHD finger transcription factor | -0.0272399 |
| TENM4 | teneurin transmembrane protein 4 | -0.0269533 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0269191 |
| TPM4 | tropomyosin 4 | -0.0266204 |
| UBC | ubiquitin C | -0.0259846 |
| IFI44L | interferon-induced protein 44-like | -0.0256783 |
| ENO1 | enolase 1, (alpha) | -0.0251854 |
| S100A9 | S100 calcium binding protein A9 | -0.0250544 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0249432 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0248389 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0247144 |
| CADM1 | cell adhesion molecule 1 | -0.0243493 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0243261 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0242588 |
| VEGFA | vascular endothelial growth factor A | -0.02414 |
| CALR | calreticulin | -0.0239793 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0237697 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0235792 |
| MLPH | melanophilin | -0.0229205 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0228721 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0227103 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.022569 |
| AHNAK | AHNAK nucleoprotein | -0.0225488 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0224352 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0222208 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0221691 |
| RPS21 | ribosomal protein S21 | -0.0218634 |
| RNF213 | ring finger protein 213 | -0.0216507 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0215858 |
| PTK2 | protein tyrosine kinase 2 | -0.0215766 |
| LOXL2 | lysyl oxidase-like 2 | -0.0215718 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0215055 |
| CCND1 | cyclin D1 | -0.0214523 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0214089 |
| KRT19 | keratin 19, type I | -0.0210453 |
| RPL35A | ribosomal protein L35a | -0.0208989 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0208637 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0208003 |
