Tangier Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [LS]. (Human Disease Ontology, DOID_1388)
External Link https://www.disgenet.org/browser/0/1/0/C0039292
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Genes

28 genes associated with the disease Tangier Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ANGPTL3 angiopoietin-like 3
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOB apolipoprotein B
APOE apolipoprotein E
CDC42 cell division cycle 42
GJA1 gap junction protein, alpha 1, 43kDa
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR162 G protein-coupled receptor 162
HEATR6 HEAT repeat containing 6
HSPG2 heparan sulfate proteoglycan 2
LCAT lecithin-cholesterol acyltransferase
LDLR low density lipoprotein receptor
NPC1 Niemann-Pick disease, type C1
NPC2 Niemann-Pick disease, type C2
PLA2G10 phospholipase A2, group X
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TERT telomerase reverse transcriptase