Tardive Dyskinesia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description the involuntary movements are tardive, meaning they have a slow or belated onset (Human Phenotype Ontology, HP_0040141)
External Link https://www.disgenet.org/browser/0/1/0/C0686347
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Genes

92 genes associated with the disease Tardive Dyskinesia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ADORA2A adenosine A2a receptor
ADORA3 adenosine A3 receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOE apolipoprotein E
ARRB2 arrestin, beta 2
BDNF brain-derived neurotrophic factor
BID BH3 interacting domain death agonist
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CRYZ crystallin, zeta (quinone reductase)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DISC1 disrupted in schizophrenia 1
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DPP6 dipeptidyl-peptidase 6
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESRRB estrogen-related receptor beta
F2R coagulation factor II (thrombin) receptor
FUZ fuzzy planar cell polarity protein
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GCH1 GTP cyclohydrolase 1
GDNF glial cell derived neurotrophic factor
GFRA2 GDNF family receptor alpha 2
GLI2 GLI family zinc finger 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPX1 glutathione peroxidase 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK6 G protein-coupled receptor kinase 6
GSK3B glycogen synthase kinase 3 beta
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HPGDS hematopoietic prostaglandin D synthase
HSPG2 heparan sulfate proteoglycan 2
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
LRP2 low density lipoprotein receptor-related protein 2
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MCF2L MCF.2 cell line derived transforming sequence-like
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRG1 neuregulin 1
NRXN1 neurexin 1
PAH phenylalanine hydroxylase
PDE4B phosphodiesterase 4B, cAMP-specific
PGP phosphoglycolate phosphatase
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PITX2 paired-like homeodomain 2
PPARG peroxisome proliferator-activated receptor gamma
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRKCD protein kinase C, delta
PRL prolactin
RGS9 regulator of G-protein signaling 9
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SOD2 superoxide dismutase 2, mitochondrial
TAAR5 trace amine associated receptor 5
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TNF tumor necrosis factor
TOR1A torsin family 1, member A (torsin A)