| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAT | plasminogen activator, tissue | 0.16514 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0954536 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.067374 |
| MYADM | myeloid-associated differentiation marker | 0.0513829 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0419465 |
| NDRG1 | N-myc downstream regulated 1 | 0.0412303 |
| HLA-B | major histocompatibility complex, class I, B | 0.0367201 |
| SBF2 | SET binding factor 2 | 0.0310866 |
| GPC6 | glypican 6 | 0.0309705 |
| COL3A1 | collagen, type III, alpha 1 | 0.0306917 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0303235 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0303139 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0297957 |
| ATP13A3 | ATPase type 13A3 | 0.0268843 |
| LOXL2 | lysyl oxidase-like 2 | 0.0261739 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0261075 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0245881 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0244427 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0242254 |
| GOLGA4 | golgin A4 | 0.024069 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0237376 |
| NAV2 | neuron navigator 2 | 0.022585 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0221038 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.022047 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0218159 |
| MYO9A | myosin IXA | 0.0215666 |
| FNIP1 | folliculin interacting protein 1 | 0.0213071 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0212511 |
| MTSS1 | metastasis suppressor 1 | 0.0202632 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0192201 |
| RASA2 | RAS p21 protein activator 2 | 0.0188609 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.018269 |
| CTSB | cathepsin B | 0.0180708 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0177832 |
| COG5 | component of oligomeric golgi complex 5 | 0.01766 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0173097 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0172693 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0172564 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.017087 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0170042 |
| MICU3 | mitochondrial calcium uptake family, member 3 | 0.0166945 |
| CD99 | CD99 molecule | 0.0166247 |
| STC1 | stanniocalcin 1 | 0.0165797 |
| FTL | ferritin, light polypeptide | 0.0163775 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0163488 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0162946 |
| HIP1 | huntingtin interacting protein 1 | 0.0161878 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0161704 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0160671 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.015843 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0157713 |
| RPS6 | ribosomal protein S6 | 0.0157109 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0155759 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0154147 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0153986 |
| SLC22A23 | solute carrier family 22, member 23 | 0.015335 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0153042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0152768 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0151991 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0151709 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0149866 |
| FRMD5 | FERM domain containing 5 | 0.0149822 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0146448 |
| RPL37A | ribosomal protein L37a | 0.0146377 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0145171 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0145008 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0144529 |
| RPS13 | ribosomal protein S13 | 0.0143831 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0143223 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0142421 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0142337 |
| ANXA4 | annexin A4 | 0.0141642 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0141475 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0140352 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0140092 |
| SH3PXD2B | SH3 and PX domains 2B | 0.0136674 |
| KIF16B | kinesin family member 16B | 0.0136162 |
| NGLY1 | N-glycanase 1 | 0.0135916 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0135867 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0135803 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0134126 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.013355 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0131573 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0131235 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0129497 |
| OPTN | optineurin | 0.0129118 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0128365 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0127994 |
| BPTF | bromodomain PHD finger transcription factor | 0.0126555 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0125423 |
| RPL31 | ribosomal protein L31 | 0.0125283 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0125139 |
| NMT2 | N-myristoyltransferase 2 | 0.0124574 |
| MAP4 | microtubule-associated protein 4 | 0.0124284 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0123846 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0122781 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0122736 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0122524 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0122503 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0122081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.228478 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.181696 |
| CDH13 | cadherin 13 | -0.174249 |
| AHNAK | AHNAK nucleoprotein | -0.166823 |
| COL5A1 | collagen, type V, alpha 1 | -0.144315 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.130983 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.129414 |
| FN1 | fibronectin 1 | -0.118588 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.118028 |
| RIGI | RNA sensor RIG-I | -0.11358 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.110414 |
| MAP1B | microtubule-associated protein 1B | -0.106549 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.101409 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.100909 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0989962 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0983787 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0953095 |
| CANX | calnexin | -0.0918467 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0834925 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0832904 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0760146 |
| FSTL1 | follistatin-like 1 | -0.0703004 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0660285 |
| NAV1 | neuron navigator 1 | -0.0650456 |
| LOX | lysyl oxidase | -0.0624908 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0622873 |
| POTEF | POTE ankyrin domain family, member F | -0.0614528 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.060983 |
| SP100 | SP100 nuclear antigen | -0.0605581 |
| PRSS23 | protease, serine, 23 | -0.0597609 |
| LDHA | lactate dehydrogenase A | -0.0596485 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0587058 |
| COL5A2 | collagen, type V, alpha 2 | -0.0586825 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0584902 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0577122 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0565062 |
| ASPH | aspartate beta-hydroxylase | -0.0544328 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0542328 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0535002 |
| MX2 | MX dynamin-like GTPase 2 | -0.0521167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0513105 |
| DCLK2 | doublecortin-like kinase 2 | -0.0488308 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0485125 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0479906 |
| DST | dystonin | -0.0472303 |
| TAGLN2 | transgelin 2 | -0.0469721 |
| EGFR | epidermal growth factor receptor | -0.0465207 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0463678 |
| EFNA5 | ephrin-A5 | -0.0459029 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0456361 |
| PKM | pyruvate kinase, muscle | -0.045217 |
| MYOF | myoferlin | -0.044751 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.044249 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0433714 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0430314 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0425248 |
| LMNA | lamin A/C | -0.0418544 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0405483 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0393104 |
| IL7R | interleukin 7 receptor | -0.0390421 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0386928 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0385975 |
| RUNX1 | runt-related transcription factor 1 | -0.0380046 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0376989 |
| TPM4 | tropomyosin 4 | -0.0370804 |
| SQSTM1 | sequestosome 1 | -0.0368967 |
| TENM3 | teneurin transmembrane protein 3 | -0.03689 |
| PLXNA2 | plexin A2 | -0.0367565 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0359273 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0358811 |
| FLNA | filamin A, alpha | -0.0351762 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0349306 |
| RNF213 | ring finger protein 213 | -0.0346624 |
| CUX1 | cut-like homeobox 1 | -0.0342913 |
| SEPTIN7 | septin 7 | -0.0341381 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0337783 |
| JUN | jun proto-oncogene | -0.0337592 |
| ANXA2 | annexin A2 | -0.0336583 |
| PCDH7 | protocadherin 7 | -0.033415 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0332567 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0330293 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.032966 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0329176 |
| TMSB10 | thymosin beta 10 | -0.0328098 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0325681 |
| TMSB4X | thymosin beta 4, X-linked | -0.032458 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0320087 |
| PRELID2 | PRELI domain containing 2 | -0.0318976 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0317421 |
| LRRC17 | leucine rich repeat containing 17 | -0.0307541 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.030473 |
| CALR | calreticulin | -0.0302292 |
| SUCNR1 | succinate receptor 1 | -0.0299206 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0290458 |
| RRBP1 | ribosome binding protein 1 | -0.0289031 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0288005 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.028792 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0287503 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0287474 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0283735 |
