| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tazarotene_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0683711 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0526842 |
| VCL | vinculin | 0.0450926 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.040943 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0368742 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0351053 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0327604 |
| PLSCR2 | phospholipid scramblase 2 | 0.0321506 |
| EGR1 | early growth response 1 | 0.0301448 |
| INTS6 | integrator complex subunit 6 | 0.0296385 |
| RNF213 | ring finger protein 213 | 0.0287804 |
| BCL2L1 | BCL2-like 1 | 0.0276883 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0259442 |
| VMP1 | vacuole membrane protein 1 | 0.0259057 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0253447 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0249743 |
| DIAPH1 | diaphanous-related formin 1 | 0.0242853 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0230866 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0217635 |
| AREG | amphiregulin | 0.0215193 |
| PADI1 | peptidyl arginine deiminase, type I | 0.020938 |
| SMAD3 | SMAD family member 3 | 0.0209306 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0199329 |
| TNS4 | tensin 4 | 0.0195137 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0190267 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0181241 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0177418 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0176086 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.017389 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0169247 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0164722 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0164681 |
| TJP1 | tight junction protein 1 | 0.0159783 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0157716 |
| CCNL1 | cyclin L1 | 0.0145655 |
| RIGI | RNA sensor RIG-I | 0.0144486 |
| POF1B | premature ovarian failure, 1B | 0.0140865 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0139618 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0139107 |
| LIMA1 | LIM domain and actin binding 1 | 0.0134768 |
| ERBIN | erbb2 interacting protein | 0.0130044 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0129005 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0127955 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0127266 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0125309 |
| PRSS22 | protease, serine, 22 | 0.0123276 |
| VIM | vimentin | 0.0123059 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0122826 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.012269 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0120135 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0116281 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0115229 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0114823 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0113794 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0112417 |
| MT2A | metallothionein 2A | 0.0112345 |
| NABP1 | nucleic acid binding protein 1 | 0.0111676 |
| MYO5B | myosin VB | 0.0111616 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0111123 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0109653 |
| RCOR1 | REST corepressor 1 | 0.0108905 |
| MYO10 | myosin X | 0.0108844 |
| DGKH | diacylglycerol kinase, eta | 0.0108046 |
| MRTFA | myocardin related transcription factor A | 0.0107884 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0107475 |
| ARHGAP27 | Rho GTPase activating protein 27 | 0.0107253 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.0106613 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0106177 |
| ATP10B | ATPase, class V, type 10B | 0.0105707 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0104491 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0101023 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.010065 |
| YAP1 | Yes-associated protein 1 | 0.00995235 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00990299 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00979956 |
| EPHA2 | EPH receptor A2 | 0.00965007 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00958093 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00955112 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00948102 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.00942276 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00941759 |
| SP100 | SP100 nuclear antigen | 0.00931042 |
| HPCAL1 | hippocalcin-like 1 | 0.00929519 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00927473 |
| HDGF | hepatoma-derived growth factor | 0.00917829 |
| HOMER1 | homer scaffolding protein 1 | 0.00914965 |
| MMP7 | matrix metallopeptidase 7 | 0.00913741 |
| NAV1 | neuron navigator 1 | 0.00908562 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00903286 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.00881973 |
| IGF2 | insulin-like growth factor 2 | 0.00880769 |
| PCDH1 | protocadherin 1 | 0.00880071 |
| DYNLT2B | dynein light chain Tctex-type 2B | 0.0086656 |
| CD68 | CD68 molecule | 0.00865265 |
| TRIM25 | tripartite motif containing 25 | 0.0086251 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.00862456 |
| CTTN | cortactin | 0.0085983 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00854691 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00847861 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00839784 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.190737 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.169235 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.144769 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13533 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.100919 |
| B2M | beta-2-microglobulin | -0.0880766 |
| AHI1 | Abelson helper integration site 1 | -0.0804788 |
| SQSTM1 | sequestosome 1 | -0.0769125 |
| CANX | calnexin | -0.075737 |
| LMO7 | LIM domain 7 | -0.0723443 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0650423 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0646357 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.063189 |
| UBC | ubiquitin C | -0.0620627 |
| HLA-B | major histocompatibility complex, class I, B | -0.0612967 |
| EZR | ezrin | -0.058935 |
| H1-0 | H1.0 linker histone | -0.0585222 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0576777 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0568343 |
| HDLBP | high density lipoprotein binding protein | -0.0539393 |
| RRBP1 | ribosome binding protein 1 | -0.0528073 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0525037 |
| PTMA | prothymosin, alpha | -0.0515898 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.050924 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0503805 |
| IRF1 | interferon regulatory factor 1 | -0.0478953 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0469662 |
| GOLGB1 | golgin B1 | -0.0464726 |
| PERP | PERP, TP53 apoptosis effector | -0.0463193 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0461255 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0461206 |
| AHNAK | AHNAK nucleoprotein | -0.0453694 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0445572 |
| LCN2 | lipocalin 2 | -0.0435985 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0433077 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0429825 |
| MORF4L2 | mortality factor 4 like 2 | -0.0422199 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0409631 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0404238 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0403616 |
| PKM | pyruvate kinase, muscle | -0.040293 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0398827 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0397228 |
| CALR | calreticulin | -0.0396239 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0393673 |
| RPL34 | ribosomal protein L34 | -0.0388687 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0386473 |
| HLA-C | major histocompatibility complex, class I, C | -0.0370817 |
| RPS6 | ribosomal protein S6 | -0.0370106 |
| SPATA13 | spermatogenesis associated 13 | -0.0366661 |
| RPLP1 | ribosomal protein, large, P1 | -0.0365848 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0365321 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0360324 |
| EPCAM | epithelial cell adhesion molecule | -0.0358246 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0352887 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0343518 |
| MYO1E | myosin IE | -0.0339305 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0333309 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330886 |
| RUNX1 | runt-related transcription factor 1 | -0.0328331 |
| RPL35A | ribosomal protein L35a | -0.0326995 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.032521 |
| JUN | jun proto-oncogene | -0.03193 |
| PHF3 | PHD finger protein 3 | -0.0318039 |
| RPL19 | ribosomal protein L19 | -0.0316106 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0311721 |
| AGR2 | anterior gradient 2 | -0.0311626 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0307793 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0307725 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0305196 |
| NF1 | neurofibromin 1 | -0.0304954 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0304746 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0304039 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0294215 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0291875 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0291778 |
| FTL | ferritin, light polypeptide | -0.0288661 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0286824 |
| RPL12 | ribosomal protein L12 | -0.0285609 |
| HLA-A | major histocompatibility complex, class I, A | -0.028526 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.028477 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0283524 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0282533 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281683 |
| HLA-E | major histocompatibility complex, class I, E | -0.0280971 |
| FUS | FUS RNA binding protein | -0.0278458 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0276075 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275987 |
| SBF2 | SET binding factor 2 | -0.0275229 |
| WDR45B | WD repeat domain 45B | -0.0273038 |
| LMAN1 | lectin, mannose-binding, 1 | -0.027282 |
| UBL3 | ubiquitin-like 3 | -0.0271634 |
| ABLIM1 | actin binding LIM protein 1 | -0.0269811 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0268998 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0263584 |
| TMEM263 | transmembrane protein 263 | -0.0263213 |
| EPHB2 | EPH receptor B2 | -0.0263174 |
| CLTC | clathrin, heavy chain (Hc) | -0.0262218 |
| SEC24D | SEC24 family member D | -0.0260005 |
| S100A10 | S100 calcium binding protein A10 | -0.0260004 |