| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.150437 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0568824 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0240907 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0169752 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0162496 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0103041 |
| FLNC | filamin C, gamma | 0.0101895 |
| HMGA1 | high mobility group AT-hook 1 | 0.00937718 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00885184 |
| RBPMS | RNA binding protein with multiple splicing | 0.00851143 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00841453 |
| EGR1 | early growth response 1 | 0.00803463 |
| PCBP1 | poly(rC) binding protein 1 | 0.00780939 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.00766276 |
| CLSTN2 | calsyntenin 2 | 0.00755988 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00728574 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0071472 |
| KAZN | kazrin, periplakin interacting protein | 0.00684766 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.00682267 |
| CFB | complement factor B | 0.00665678 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00627318 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00620275 |
| CADM1 | cell adhesion molecule 1 | 0.0057015 |
| FAM20C | family with sequence similarity 20, member C | 0.00551606 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00527839 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0051634 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00495429 |
| RASA2 | RAS p21 protein activator 2 | 0.00493696 |
| MSI2 | musashi RNA-binding protein 2 | 0.00489037 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00483155 |
| TMEM39A | transmembrane protein 39A | 0.00460264 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.004585 |
| ARF1 | ADP-ribosylation factor 1 | 0.0045024 |
| CEP95 | centrosomal protein 95kDa | 0.00446443 |
| NRP2 | neuropilin 2 | 0.00446088 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.00441812 |
| GANAB | glucosidase, alpha; neutral AB | 0.00440441 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00438557 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00437201 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00435125 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00428629 |
| RAI14 | retinoic acid induced 14 | 0.00427469 |
| FNIP1 | folliculin interacting protein 1 | 0.00424084 |
| RAB5B | RAB5B, member RAS oncogene family | 0.0042386 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00423467 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00420521 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00415029 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.00406851 |
| GPC6 | glypican 6 | 0.00404013 |
| KIAA1755 | KIAA1755 | 0.00402897 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00400978 |
| RARB | retinoic acid receptor, beta | 0.00398569 |
| URI1 | URI1, prefoldin-like chaperone | 0.00394792 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0039389 |
| TOM1 | target of myb1 (chicken) | 0.00393536 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00388358 |
| USP37 | ubiquitin specific peptidase 37 | 0.00386045 |
| RNF185 | ring finger protein 185 | 0.00380245 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.00375667 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.00372536 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.003683 |
| SULF1 | sulfatase 1 | 0.00366577 |
| PLXNB2 | plexin B2 | 0.00365392 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.00360749 |
| PLAT | plasminogen activator, tissue | 0.00355163 |
| HMBOX1 | homeobox containing 1 | 0.00353082 |
| CDK13 | cyclin-dependent kinase 13 | 0.00351198 |
| GTPBP2 | GTP binding protein 2 | 0.00350602 |
| RNF169 | ring finger protein 169 | 0.003495 |
| ZNF33B | zinc finger protein 33B | 0.00348013 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.0034791 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.00347889 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00347199 |
| SYNJ1 | synaptojanin 1 | 0.00345279 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00344633 |
| SCARA3 | scavenger receptor class A, member 3 | 0.00344204 |
| POU2F1 | POU class 2 homeobox 1 | 0.00342694 |
| CRY1 | cryptochrome circadian clock 1 | 0.00341889 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | 0.00341556 |
| TRAPPC8 | trafficking protein particle complex 8 | 0.00341383 |
| MXRA7 | matrix-remodelling associated 7 | 0.00337848 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.00337363 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00326785 |
| TRIB2 | tribbles pseudokinase 2 | 0.00324899 |
| SLC25A42 | solute carrier family 25, member 42 | 0.0032361 |
| STAC | SH3 and cysteine rich domain | 0.00323043 |
| DCTN1 | dynactin 1 | 0.00322242 |
| FASN | fatty acid synthase | 0.00321619 |
| TOX | thymocyte selection-associated high mobility group box | 0.00321106 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.00319382 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.00318734 |
| SPOCD1 | SPOC domain containing 1 | 0.00318 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.00317861 |
| PLBD2 | phospholipase B domain containing 2 | 0.0031776 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00317425 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00316732 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00315264 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.00312767 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | 0.00312166 |
| IL1B | interleukin 1, beta | 0.00303398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.203908 |
| MT2A | metallothionein 2A | -0.124581 |
| COL1A1 | collagen, type I, alpha 1 | -0.12099 |
| FN1 | fibronectin 1 | -0.119511 |
| VIM | vimentin | -0.117734 |
| CD44 | CD44 molecule (Indian blood group) | -0.115466 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.106158 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0998261 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0991443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0941978 |
| COL1A2 | collagen, type I, alpha 2 | -0.0809633 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.073008 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0526071 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0521011 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.05137 |
| ASPH | aspartate beta-hydroxylase | -0.0504461 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0500211 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0479498 |
| TPM4 | tropomyosin 4 | -0.0470398 |
| VEGFA | vascular endothelial growth factor A | -0.047026 |
| EXT1 | exostosin glycosyltransferase 1 | -0.046337 |
| CALR | calreticulin | -0.0462832 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0459802 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0447115 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0443821 |
| IER3 | immediate early response 3 | -0.0439201 |
| CDH13 | cadherin 13 | -0.0425263 |
| LOXL2 | lysyl oxidase-like 2 | -0.0405502 |
| B2M | beta-2-microglobulin | -0.0404877 |
| STC1 | stanniocalcin 1 | -0.0399426 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0379338 |
| CANX | calnexin | -0.0371909 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0371558 |
| TMSB10 | thymosin beta 10 | -0.0356687 |
| ENO1 | enolase 1, (alpha) | -0.0355959 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0355334 |
| PTMA | prothymosin, alpha | -0.0354435 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.035423 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0350443 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0344905 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0340136 |
| RPS8 | ribosomal protein S8 | -0.0339017 |
| AHNAK | AHNAK nucleoprotein | -0.0338593 |
| FTL | ferritin, light polypeptide | -0.0328154 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0323046 |
| CALU | calumenin | -0.0320596 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0314823 |
| IL6ST | interleukin 6 signal transducer | -0.0311724 |
| POSTN | periostin, osteoblast specific factor | -0.0306946 |
| PKM | pyruvate kinase, muscle | -0.0305987 |
| FBN1 | fibrillin 1 | -0.0295891 |
| MAP1B | microtubule-associated protein 1B | -0.0295351 |
| HMGA2 | high mobility group AT-hook 2 | -0.0292751 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0292622 |
| PDE10A | phosphodiesterase 10A | -0.0290927 |
| UBC | ubiquitin C | -0.028939 |
| NDRG1 | N-myc downstream regulated 1 | -0.0284571 |
| LDHA | lactate dehydrogenase A | -0.0280928 |
| INHBA | inhibin, beta A | -0.0280184 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0277424 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0271391 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0266999 |
| ECE1 | endothelin converting enzyme 1 | -0.0262959 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0262484 |
| RPS2 | ribosomal protein S2 | -0.0257537 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0256665 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0255102 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0254338 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0251643 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0251004 |
| MT1X | metallothionein 1X | -0.0246266 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0243611 |
| TMSB4X | thymosin beta 4, X-linked | -0.0243517 |
| PGK1 | phosphoglycerate kinase 1 | -0.0239034 |
| RPS6 | ribosomal protein S6 | -0.0233541 |
| RPL8 | ribosomal protein L8 | -0.0230785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0229208 |
| DST | dystonin | -0.0228768 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0227794 |
| PTK2 | protein tyrosine kinase 2 | -0.02277 |
| S100A9 | S100 calcium binding protein A9 | -0.0220188 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0218657 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0218623 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0213405 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0213404 |
| NAV1 | neuron navigator 1 | -0.0206003 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0202969 |
| COL5A1 | collagen, type V, alpha 1 | -0.0202754 |
| CALD1 | caldesmon 1 | -0.0202416 |
| SDC2 | syndecan 2 | -0.0202373 |
| CLIC4 | chloride intracellular channel 4 | -0.0202261 |
| RPL19 | ribosomal protein L19 | -0.0200675 |
| S100A10 | S100 calcium binding protein A10 | -0.019932 |
| GLIS3 | GLIS family zinc finger 3 | -0.0198973 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.019746 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0197074 |
| RPS3 | ribosomal protein S3 | -0.0193748 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0191275 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0190627 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0189851 |
