| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tazarotene_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0723394 |
| MEF2A | myocyte enhancer factor 2A | 0.0626509 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.062435 |
| MYOF | myoferlin | 0.0566823 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0532499 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0487524 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0433795 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0370441 |
| RAI14 | retinoic acid induced 14 | 0.0370036 |
| AOPEP | aminopeptidase O (putative) | 0.036309 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.035603 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0327014 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0311245 |
| MTSS1 | metastasis suppressor 1 | 0.0296867 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.02945 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0279793 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0274602 |
| FN1 | fibronectin 1 | 0.0272741 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0264 |
| NFIA | nuclear factor I/A | 0.0258367 |
| ARRDC3 | arrestin domain containing 3 | 0.025413 |
| ZNF292 | zinc finger protein 292 | 0.0241325 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0240991 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0238159 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.023472 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0231507 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.022343 |
| RNF145 | ring finger protein 145 | 0.0222965 |
| QKI | QKI, KH domain containing, RNA binding | 0.0218261 |
| HELZ | helicase with zinc finger | 0.0217944 |
| EFNA5 | ephrin-A5 | 0.0217692 |
| TMF1 | TATA element modulatory factor 1 | 0.0210568 |
| PTK2 | protein tyrosine kinase 2 | 0.0208664 |
| TGM2 | transglutaminase 2 | 0.0207899 |
| ZNF638 | zinc finger protein 638 | 0.0207847 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0207788 |
| DOK5 | docking protein 5 | 0.0206953 |
| LOXL2 | lysyl oxidase-like 2 | 0.0205532 |
| ANLN | anillin, actin binding protein | 0.0202296 |
| GRAMD1B | GRAM domain containing 1B | 0.0201239 |
| FOXP1 | forkhead box P1 | 0.0201042 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0200636 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0198509 |
| SRP54 | signal recognition particle 54kDa | 0.0196193 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0185014 |
| SUCO | SUN domain containing ossification factor | 0.0183475 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0181383 |
| HDLBP | high density lipoprotein binding protein | 0.0178808 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0178425 |
| FBXO42 | F-box protein 42 | 0.0176873 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0175273 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0175162 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0174752 |
| CANX | calnexin | 0.0174515 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0173818 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0172121 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.017148 |
| SMOX | spermine oxidase | 0.0171397 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0170218 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0170126 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0167696 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0167085 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0165834 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0165707 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0164777 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0163417 |
| ATM | ATM serine/threonine kinase | 0.0162745 |
| RND3 | Rho family GTPase 3 | 0.0161589 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0160582 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0157451 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.0155727 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0155455 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0154984 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0154897 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.015481 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.015464 |
| BARX2 | BARX homeobox 2 | 0.0154421 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0153958 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.015383 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0152656 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0152569 |
| JAG1 | jagged 1 | 0.0152161 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0151852 |
| TRAM1 | translocation associated membrane protein 1 | 0.0151289 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0151213 |
| TNPO1 | transportin 1 | 0.0150753 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.015011 |
| ZFR | zinc finger RNA binding protein | 0.0146838 |
| PCM1 | pericentriolar material 1 | 0.0146693 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0146627 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0146447 |
| USP24 | ubiquitin specific peptidase 24 | 0.0144987 |
| USP12 | ubiquitin specific peptidase 12 | 0.0144941 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0144463 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0143734 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0142993 |
| PHKB | phosphorylase kinase, beta | 0.0142184 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0141597 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0141404 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0141259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.312278 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.165989 |
| POTEF | POTE ankyrin domain family, member F | -0.133625 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126712 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.119016 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.110037 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0996699 |
| B2M | beta-2-microglobulin | -0.0883612 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.08691 |
| EGR1 | early growth response 1 | -0.0791605 |
| S100A10 | S100 calcium binding protein A10 | -0.0752079 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0726703 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0722479 |
| HLA-B | major histocompatibility complex, class I, B | -0.068256 |
| LDHA | lactate dehydrogenase A | -0.0676566 |
| LAMC2 | laminin, gamma 2 | -0.0670043 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0663997 |
| RPS21 | ribosomal protein S21 | -0.0640397 |
| VCL | vinculin | -0.059974 |
| RPS24 | ribosomal protein S24 | -0.0594766 |
| RIGI | RNA sensor RIG-I | -0.0546702 |
| TMSB10 | thymosin beta 10 | -0.0543871 |
| ACTN4 | actinin, alpha 4 | -0.0536288 |
| ANXA2 | annexin A2 | -0.0527552 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0495754 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0494203 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0493451 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0490961 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.047214 |
| LMNA | lamin A/C | -0.0467713 |
| PODXL | podocalyxin-like | -0.0466923 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0462433 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0458496 |
| PGK1 | phosphoglycerate kinase 1 | -0.0446817 |
| RASAL2 | RAS protein activator like 2 | -0.0443222 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0441695 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0428676 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0426775 |
| RPL11 | ribosomal protein L11 | -0.0416985 |
| MT2A | metallothionein 2A | -0.0416059 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0408101 |
| PLS3 | plastin 3 | -0.0407805 |
| FOSL1 | FOS-like antigen 1 | -0.0406702 |
| RPS8 | ribosomal protein S8 | -0.0404888 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.040365 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0402999 |
| RPL37 | ribosomal protein L37 | -0.0397164 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0386931 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0386476 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0385757 |
| RPS13 | ribosomal protein S13 | -0.0385675 |
| CD44 | CD44 molecule (Indian blood group) | -0.0384041 |
| LUZP1 | leucine zipper protein 1 | -0.0382282 |
| KRT17 | keratin 17, type I | -0.0376491 |
| CLIC4 | chloride intracellular channel 4 | -0.0368678 |
| ACTG1 | actin gamma 1 | -0.0368517 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0366899 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0365662 |
| EMP1 | epithelial membrane protein 1 | -0.0365133 |
| IGF2 | insulin-like growth factor 2 | -0.0358893 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0358558 |
| ITGA6 | integrin, alpha 6 | -0.0358028 |
| CD9 | CD9 molecule | -0.0353928 |
| FLNB | filamin B, beta | -0.035238 |
| RPL37A | ribosomal protein L37a | -0.0350455 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0348907 |
| RCOR1 | REST corepressor 1 | -0.0335061 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0334781 |
| GNAS | GNAS complex locus | -0.0332654 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0332597 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0332223 |
| ACTN1 | actinin, alpha 1 | -0.0329761 |
| ENO1 | enolase 1, (alpha) | -0.0326697 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0324039 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0313704 |
| RPLP0 | ribosomal protein, large, P0 | -0.0312637 |
| S100A11 | S100 calcium binding protein A11 | -0.031028 |
| RPL9 | ribosomal protein L9 | -0.0309037 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0307969 |
| VDAC1 | voltage-dependent anion channel 1 | -0.030665 |
| RPS25 | ribosomal protein S25 | -0.0304435 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0303903 |
| INTS6 | integrator complex subunit 6 | -0.0301637 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0299388 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0297405 |
| RPLP2 | ribosomal protein, large, P2 | -0.0293462 |
| KRT14 | keratin 14, type I | -0.0293458 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0291472 |
| MIDN | midnolin | -0.0291202 |
| CALU | calumenin | -0.0287952 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0282297 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0281485 |
| S100A9 | S100 calcium binding protein A9 | -0.0281382 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0275286 |
| TXNIP | thioredoxin interacting protein | -0.0274995 |
| RPL34 | ribosomal protein L34 | -0.0273884 |
| POMP | proteasome maturation protein | -0.027225 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0272009 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0269262 |
| S100A2 | S100 calcium binding protein A2 | -0.0268188 |
