| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tazarotene_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.032543 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0265728 |
| MKI67 | marker of proliferation Ki-67 | 0.0255034 |
| RUNX1 | runt-related transcription factor 1 | 0.0225499 |
| NGLY1 | N-glycanase 1 | 0.0215483 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0210704 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0204913 |
| TMEM165 | transmembrane protein 165 | 0.0183058 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0167297 |
| OGA | O-GlcNAcase | 0.0166208 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0160593 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0160179 |
| DTNA | dystrobrevin, alpha | 0.0157549 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0152708 |
| RNF145 | ring finger protein 145 | 0.0146716 |
| HELZ | helicase with zinc finger | 0.0143595 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0143016 |
| SRP54 | signal recognition particle 54kDa | 0.0135483 |
| ARRDC3 | arrestin domain containing 3 | 0.0132737 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0121606 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0121259 |
| ATP13A3 | ATPase type 13A3 | 0.0121099 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0120452 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0116511 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0106454 |
| CES1 | carboxylesterase 1 | 0.010288 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0101243 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00973667 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00970462 |
| TMF1 | TATA element modulatory factor 1 | 0.00957644 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.00913702 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00910113 |
| NCKAP1 | NCK-associated protein 1 | 0.00900198 |
| CENPF | centromere protein F, 350/400kDa | 0.00895484 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.00894501 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00891543 |
| NUP58 | nucleoporin 58 | 0.00881363 |
| RBM26 | RNA binding motif protein 26 | 0.00875202 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.00854082 |
| NBAS | neuroblastoma amplified sequence | 0.00837588 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.00836301 |
| NPTN | neuroplastin | 0.0083523 |
| CCNL1 | cyclin L1 | 0.00833454 |
| SMC4 | structural maintenance of chromosomes 4 | 0.00820085 |
| HYOU1 | hypoxia up-regulated 1 | 0.00815285 |
| ZNF292 | zinc finger protein 292 | 0.0080731 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.00785531 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00782277 |
| SEC24A | SEC24 family member A | 0.00774102 |
| FNIP1 | folliculin interacting protein 1 | 0.00753572 |
| TBK1 | TANK-binding kinase 1 | 0.00741619 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00740827 |
| YEATS2 | YEATS domain containing 2 | 0.00732505 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00732221 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00732179 |
| PNN | pinin, desmosome associated protein | 0.00724988 |
| PER1 | period circadian clock 1 | 0.00715162 |
| ZNF638 | zinc finger protein 638 | 0.00713958 |
| RBM39 | RNA binding motif protein 39 | 0.0070459 |
| TFG | TRK-fused gene | 0.00701839 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.00686125 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0068585 |
| FOXJ3 | forkhead box J3 | 0.0068214 |
| TOP1 | topoisomerase (DNA) I | 0.00672964 |
| RBM25 | RNA binding motif protein 25 | 0.00670089 |
| USP47 | ubiquitin specific peptidase 47 | 0.0066784 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00664505 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00664007 |
| GOLGA4 | golgin A4 | 0.00657934 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.00651971 |
| YTHDC1 | YTH domain containing 1 | 0.00647513 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00643949 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00630902 |
| MIS18BP1 | MIS18 binding protein 1 | 0.00626792 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.00624748 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.00622058 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.00621593 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.00620553 |
| USP24 | ubiquitin specific peptidase 24 | 0.00619579 |
| ZNF148 | zinc finger protein 148 | 0.00616656 |
| SEPTIN2 | septin 2 | 0.00614703 |
| NEK7 | NIMA-related kinase 7 | 0.0060588 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.00604809 |
| METTL15 | methyltransferase like 15 | 0.00604117 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00600236 |
| GPATCH2L | G patch domain containing 2-like | 0.00599921 |
| FAM117B | family with sequence similarity 117, member B | 0.0059926 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0059677 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.00596416 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.00595093 |
| SGO2 | shugoshin 2 | 0.00593038 |
| ANKRD37 | ankyrin repeat domain 37 | 0.00591647 |
| RTN4 | reticulon 4 | 0.00586229 |
| CENPE | centromere protein E, 312kDa | 0.00586113 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.00585586 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.00581193 |
| PCNX1 | pecanex 1 | 0.00578674 |
| TMEM39A | transmembrane protein 39A | 0.00578578 |
| ZFR | zinc finger RNA binding protein | 0.00578377 |
| CKAP5 | cytoskeleton associated protein 5 | 0.00575221 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.281259 |
| EGFR | epidermal growth factor receptor | -0.238717 |
| ASPH | aspartate beta-hydroxylase | -0.121827 |
| LMO7 | LIM domain 7 | -0.109987 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.107755 |
| TMSB10 | thymosin beta 10 | -0.105087 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0950739 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0816633 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0811637 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0758552 |
| LAMC2 | laminin, gamma 2 | -0.0746636 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0676753 |
| S100A10 | S100 calcium binding protein A10 | -0.0673153 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0642867 |
| LDHA | lactate dehydrogenase A | -0.0633972 |
| ACTG1 | actin gamma 1 | -0.0612312 |
| PKM | pyruvate kinase, muscle | -0.0606968 |
| AHNAK | AHNAK nucleoprotein | -0.0602578 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0590571 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.058844 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0561091 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0540316 |
| ANXA2 | annexin A2 | -0.0524687 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.052011 |
| TXNRD1 | thioredoxin reductase 1 | -0.0504223 |
| EFNA5 | ephrin-A5 | -0.0494282 |
| STC1 | stanniocalcin 1 | -0.046321 |
| RNF213 | ring finger protein 213 | -0.0460319 |
| KRT18 | keratin 18, type I | -0.0451986 |
| KRT7 | keratin 7, type II | -0.0434805 |
| INTS6 | integrator complex subunit 6 | -0.0433876 |
| ENO1 | enolase 1, (alpha) | -0.0427476 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0417709 |
| MYO1E | myosin IE | -0.040941 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0404565 |
| PATJ | PATJ crumbs cell polarity complex component | -0.040268 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0399145 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0397034 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0386394 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0384791 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0384153 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0379075 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0377702 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0377491 |
| CST3 | cystatin C | -0.0376743 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0373537 |
| SLTM | SAFB-like, transcription modulator | -0.0372373 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0357115 |
| OSMR | oncostatin M receptor | -0.0354074 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0342556 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0340797 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0340556 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0330331 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0328796 |
| PTMA | prothymosin, alpha | -0.032813 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0328123 |
| SP100 | SP100 nuclear antigen | -0.032297 |
| RPS24 | ribosomal protein S24 | -0.0320698 |
| CPE | carboxypeptidase E | -0.0318254 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0318237 |
| CCND1 | cyclin D1 | -0.0317893 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0308519 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.030808 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0305892 |
| DSPP | dentin sialophosphoprotein | -0.0303367 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0298806 |
| CUX1 | cut-like homeobox 1 | -0.0292159 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0288666 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0284663 |
| B2M | beta-2-microglobulin | -0.0283894 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281644 |
| UBC | ubiquitin C | -0.0280915 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.027891 |
| MYO1D | myosin ID | -0.0277515 |
| VCL | vinculin | -0.0275242 |
| KRT8 | keratin 8, type II | -0.0275075 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0274896 |
| H1-0 | H1.0 linker histone | -0.0274158 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0269247 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0265488 |
| TPM4 | tropomyosin 4 | -0.0264651 |
| FBXO11 | F-box protein 11 | -0.0261335 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0260507 |
| AREG | amphiregulin | -0.0257293 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0257269 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0250656 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0250287 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0249513 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0248921 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0248737 |
| TRIM56 | tripartite motif containing 56 | -0.0248219 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0248094 |
| LAMB3 | laminin, beta 3 | -0.0247122 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0243096 |
| HLA-B | major histocompatibility complex, class I, B | -0.0242464 |
| DSCAM | Down syndrome cell adhesion molecule | -0.02388 |
| EGR1 | early growth response 1 | -0.0234133 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.023328 |
| SCEL | sciellin | -0.0232875 |
| RPS25 | ribosomal protein S25 | -0.0231286 |
