| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tazarotene_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0921924 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0690608 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0511639 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0442363 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0392073 |
| VEGFA | vascular endothelial growth factor A | 0.0287973 |
| MTSS1 | metastasis suppressor 1 | 0.0281371 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0279681 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0251866 |
| EGR1 | early growth response 1 | 0.0236891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0233406 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0218545 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0212628 |
| FN1 | fibronectin 1 | 0.0204258 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0199472 |
| NDRG1 | N-myc downstream regulated 1 | 0.0193579 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0192608 |
| PYGL | phosphorylase, glycogen, liver | 0.0182722 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.01808 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0180609 |
| AADAC | arylacetamide deacetylase | 0.0171697 |
| TGM2 | transglutaminase 2 | 0.0170163 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0167776 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0167481 |
| FAM20C | family with sequence similarity 20, member C | 0.0165936 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0162936 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0162704 |
| CMIP | c-Maf inducing protein | 0.015409 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0152353 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0147912 |
| IL1B | interleukin 1, beta | 0.0140864 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0135146 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0134195 |
| OPTN | optineurin | 0.0128098 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0126332 |
| EGFR | epidermal growth factor receptor | 0.0122984 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0122803 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0122002 |
| PGM3 | phosphoglucomutase 3 | 0.0121413 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.012133 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0120055 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0119915 |
| PMM2 | phosphomannomutase 2 | 0.0119458 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0119453 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0116827 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0116166 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.011587 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0115792 |
| C1R | complement component 1, r subcomponent | 0.0115225 |
| FNIP1 | folliculin interacting protein 1 | 0.0114232 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0113803 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0113796 |
| PRRX1 | paired related homeobox 1 | 0.0113786 |
| NHSL1 | NHS-like 1 | 0.0111933 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.01113 |
| ZNF146 | zinc finger protein 146 | 0.0111276 |
| TNS1 | tensin 1 | 0.0108816 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.0108041 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0107562 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0107519 |
| NGRN | neugrin, neurite outgrowth associated | 0.0107246 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0107217 |
| HDAC9 | histone deacetylase 9 | 0.0105158 |
| RNF217 | ring finger protein 217 | 0.0103532 |
| STC1 | stanniocalcin 1 | 0.0103148 |
| FBN1 | fibrillin 1 | 0.0102654 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0102138 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0101838 |
| FAM107B | family with sequence similarity 107, member B | 0.0101522 |
| MYADM | myeloid-associated differentiation marker | 0.010132 |
| CDK14 | cyclin-dependent kinase 14 | 0.0101143 |
| NAV2 | neuron navigator 2 | 0.0100742 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0100154 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0099791 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00996192 |
| PODXL | podocalyxin-like | 0.00995839 |
| SH3RF3 | SH3 domain containing ring finger 3 | 0.00988518 |
| ATP9A | ATPase, class II, type 9A | 0.00953222 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00950392 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00942361 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00942242 |
| SLC44A5 | solute carrier family 44, member 5 | 0.00942163 |
| COL7A1 | collagen, type VII, alpha 1 | 0.009417 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00935658 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00935028 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.00928468 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00926323 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0092514 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.00915976 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0091347 |
| IGF2 | insulin-like growth factor 2 | 0.00892202 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.00887366 |
| TMEM165 | transmembrane protein 165 | 0.00887063 |
| SEPTIN9 | septin 9 | 0.00871393 |
| FAM193A | family with sequence similarity 193, member A | 0.00867309 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00863387 |
| SEC24A | SEC24 family member A | 0.00862358 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.00850193 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.00849327 |
| UBAP2 | ubiquitin associated protein 2 | 0.00848239 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.231066 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.225111 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.218292 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.161208 |
| CD44 | CD44 molecule (Indian blood group) | -0.110592 |
| FTL | ferritin, light polypeptide | -0.0964487 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0841863 |
| VIM | vimentin | -0.0761325 |
| TMSB10 | thymosin beta 10 | -0.0727493 |
| PTMA | prothymosin, alpha | -0.0712084 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0704095 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0656921 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0648559 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0643155 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0603996 |
| IER3 | immediate early response 3 | -0.0561854 |
| RBM39 | RNA binding motif protein 39 | -0.0548595 |
| CANX | calnexin | -0.0529829 |
| AHNAK | AHNAK nucleoprotein | -0.0507982 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0503244 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0501187 |
| RPS24 | ribosomal protein S24 | -0.0493292 |
| RPLP1 | ribosomal protein, large, P1 | -0.0478369 |
| OGA | O-GlcNAcase | -0.0464906 |
| PRELID2 | PRELI domain containing 2 | -0.0462403 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0451593 |
| PARD3 | par-3 family cell polarity regulator | -0.0451074 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0450668 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0424362 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.041296 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.040626 |
| USP3 | ubiquitin specific peptidase 3 | -0.040501 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0404481 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0401053 |
| RPL35A | ribosomal protein L35a | -0.0399502 |
| RPLP0 | ribosomal protein, large, P0 | -0.0399273 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0397119 |
| MT2A | metallothionein 2A | -0.0390817 |
| FAM13A | family with sequence similarity 13, member A | -0.0387987 |
| H1-0 | H1.0 linker histone | -0.0381822 |
| GPC6 | glypican 6 | -0.0381582 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0381274 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0380031 |
| RPS21 | ribosomal protein S21 | -0.037297 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0362354 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0359041 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0353464 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.035119 |
| RPL32 | ribosomal protein L32 | -0.0348884 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0341067 |
| ATP13A3 | ATPase type 13A3 | -0.0334961 |
| RPS11 | ribosomal protein S11 | -0.0328103 |
| TXNRD1 | thioredoxin reductase 1 | -0.0326642 |
| RPS8 | ribosomal protein S8 | -0.0326514 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0324778 |
| RPS19 | ribosomal protein S19 | -0.0324091 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0323645 |
| SMAD3 | SMAD family member 3 | -0.0319968 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0317631 |
| YBX1 | Y box binding protein 1 | -0.0317546 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0309014 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0307913 |
| UBC | ubiquitin C | -0.030546 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0304681 |
| RPL23 | ribosomal protein L23 | -0.0304388 |
| ADD3 | adducin 3 (gamma) | -0.030438 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.030333 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0300618 |
| TMEM263 | transmembrane protein 263 | -0.0300062 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0296736 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0294621 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0294116 |
| RPL34 | ribosomal protein L34 | -0.0293911 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.029346 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0292434 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0291823 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0291408 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0291378 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0285747 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0284945 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.028337 |
| PGK1 | phosphoglycerate kinase 1 | -0.0282593 |
| ENO1 | enolase 1, (alpha) | -0.0279951 |
| MAP1B | microtubule-associated protein 1B | -0.0279134 |
| GPHN | gephyrin | -0.027357 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0272226 |
| RPLP2 | ribosomal protein, large, P2 | -0.0272188 |
| ZNF292 | zinc finger protein 292 | -0.0271271 |
| WDR45B | WD repeat domain 45B | -0.0270574 |
| RPL12 | ribosomal protein L12 | -0.0269702 |
| GNAS | GNAS complex locus | -0.0267682 |
| USP34 | ubiquitin specific peptidase 34 | -0.0266881 |
| RPS6 | ribosomal protein S6 | -0.0266662 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0265289 |
| HDLBP | high density lipoprotein binding protein | -0.0264827 |
| RLF | rearranged L-myc fusion | -0.0262674 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0259129 |
| RPS25 | ribosomal protein S25 | -0.0257771 |
| RPL19 | ribosomal protein L19 | -0.0253982 |
| YBX3 | Y box binding protein 3 | -0.0253492 |
