| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tazarotene_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.12969 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.118682 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0491337 |
| EGR1 | early growth response 1 | 0.0490705 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0418375 |
| CMIP | c-Maf inducing protein | 0.0374467 |
| PYGL | phosphorylase, glycogen, liver | 0.036836 |
| POTEF | POTE ankyrin domain family, member F | 0.0356154 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0332573 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0330511 |
| FLNB | filamin B, beta | 0.0320294 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0309978 |
| HLA-B | major histocompatibility complex, class I, B | 0.0302535 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0302283 |
| NDRG1 | N-myc downstream regulated 1 | 0.0301476 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0296415 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0295759 |
| MCL1 | myeloid cell leukemia 1 | 0.0294793 |
| HDAC9 | histone deacetylase 9 | 0.0283695 |
| HLA-A | major histocompatibility complex, class I, A | 0.0281174 |
| EGFR | epidermal growth factor receptor | 0.0279732 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0273599 |
| USP36 | ubiquitin specific peptidase 36 | 0.0266054 |
| BRD2 | bromodomain containing 2 | 0.0260807 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0255799 |
| HDGF | hepatoma-derived growth factor | 0.024778 |
| ATF4 | activating transcription factor 4 | 0.0238444 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0234776 |
| PFN1 | profilin 1 | 0.0218185 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0215885 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0200683 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0200395 |
| MSN | moesin | 0.0200365 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0197964 |
| STC2 | stanniocalcin 2 | 0.0191436 |
| TGFB2 | transforming growth factor, beta 2 | 0.0184645 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0184425 |
| LDHA | lactate dehydrogenase A | 0.0183205 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0182471 |
| MYO1E | myosin IE | 0.0181589 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0180711 |
| TPM3 | tropomyosin 3 | 0.01802 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0179441 |
| GON4L | gon-4-like (C. elegans) | 0.017716 |
| SRP54 | signal recognition particle 54kDa | 0.0176528 |
| ANGPTL4 | angiopoietin-like 4 | 0.0176308 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0174864 |
| COPA | coatomer protein complex, subunit alpha | 0.017312 |
| FAM193A | family with sequence similarity 193, member A | 0.017256 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0170551 |
| MYADM | myeloid-associated differentiation marker | 0.0168689 |
| DOCK5 | dedicator of cytokinesis 5 | 0.016656 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0165941 |
| FMNL2 | formin-like 2 | 0.0165928 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0165107 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0160319 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0159787 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0155339 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0152821 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0150165 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0149808 |
| MAX | MYC associated factor X | 0.0146848 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0144699 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0140093 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0139256 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0139028 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0138618 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0138216 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0136621 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0136608 |
| INHBA | inhibin, beta A | 0.0135803 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0135405 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0134956 |
| USP8 | ubiquitin specific peptidase 8 | 0.0134271 |
| CTBP2 | C-terminal binding protein 2 | 0.0134247 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0133699 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0133624 |
| TGM2 | transglutaminase 2 | 0.0133341 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.013245 |
| DCTN1 | dynactin 1 | 0.0131179 |
| TPM1 | tropomyosin 1 (alpha) | 0.0130762 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0130199 |
| CCNL1 | cyclin L1 | 0.0130153 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0130092 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | 0.0129721 |
| PCBP1 | poly(rC) binding protein 1 | 0.012936 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0128843 |
| IER2 | immediate early response 2 | 0.0128815 |
| JUN | jun proto-oncogene | 0.012831 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0128167 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0127558 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0125529 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0125481 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0124772 |
| INTS6 | integrator complex subunit 6 | 0.0124562 |
| UBE4B | ubiquitination factor E4B | 0.0124376 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.012374 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0123581 |
| VEGFA | vascular endothelial growth factor A | 0.0122458 |
| WASF2 | WAS protein family, member 2 | 0.0122073 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.214428 |
| FTL | ferritin, light polypeptide | -0.190319 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.172555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.167237 |
| PM20D1 | peptidase M20 domain containing 1 | -0.152824 |
| TXNRD1 | thioredoxin reductase 1 | -0.147801 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.126324 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.113019 |
| RPL19 | ribosomal protein L19 | -0.0996725 |
| TMSB10 | thymosin beta 10 | -0.0867701 |
| GRAMD1B | GRAM domain containing 1B | -0.0851738 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0803851 |
| MT2A | metallothionein 2A | -0.0791263 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0768802 |
| RPL23 | ribosomal protein L23 | -0.0740622 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0724115 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0705275 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0696341 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0687393 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.06812 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0609068 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0591713 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0586529 |
| RPS21 | ribosomal protein S21 | -0.0560506 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0558169 |
| AHNAK | AHNAK nucleoprotein | -0.0535699 |
| ASPH | aspartate beta-hydroxylase | -0.051108 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0510061 |
| RPLP0 | ribosomal protein, large, P0 | -0.0500041 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0494998 |
| FGB | fibrinogen beta chain | -0.0486414 |
| S100A10 | S100 calcium binding protein A10 | -0.0463514 |
| WWOX | WW domain containing oxidoreductase | -0.0453032 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0444234 |
| IER3 | immediate early response 3 | -0.0441305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436555 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0434169 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0421129 |
| USP3 | ubiquitin specific peptidase 3 | -0.0412476 |
| ANXA2 | annexin A2 | -0.038858 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.038799 |
| RPS24 | ribosomal protein S24 | -0.0383516 |
| RPS5 | ribosomal protein S5 | -0.0381773 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0374553 |
| TNPO1 | transportin 1 | -0.0372832 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.037176 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0370155 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0367291 |
| TMEM123 | transmembrane protein 123 | -0.0350253 |
| PTMA | prothymosin, alpha | -0.0346736 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0343234 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0342254 |
| EFNA5 | ephrin-A5 | -0.0339723 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0338311 |
| RPL8 | ribosomal protein L8 | -0.0333848 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0330165 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0324922 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0323919 |
| BICC1 | BicC family RNA binding protein 1 | -0.0323559 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0308974 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.030735 |
| FUS | FUS RNA binding protein | -0.0305585 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0305584 |
| NRG1 | neuregulin 1 | -0.0299675 |
| HMGB1 | high mobility group box 1 | -0.0299468 |
| AHR | aryl hydrocarbon receptor | -0.0298326 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.029561 |
| MIS18BP1 | MIS18 binding protein 1 | -0.029478 |
| DEK | DEK proto-oncogene | -0.0290672 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0289844 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0288809 |
| APP | amyloid beta (A4) precursor protein | -0.0288108 |
| CANX | calnexin | -0.0286662 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0285477 |
| RPS25 | ribosomal protein S25 | -0.028537 |
| TUBB | tubulin, beta class I | -0.0282906 |
| SERF2 | small EDRK-rich factor 2 | -0.0282891 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0282385 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0280528 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0277348 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0276432 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0273231 |
| YME1L1 | YME1-like 1 ATPase | -0.0273216 |
| YBX1 | Y box binding protein 1 | -0.02727 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0270706 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.027012 |
| RPL34 | ribosomal protein L34 | -0.0268288 |
| RPS19 | ribosomal protein S19 | -0.0264598 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.026256 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0261889 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0259318 |
| POU2F1 | POU class 2 homeobox 1 | -0.0258489 |
| ECT2 | epithelial cell transforming 2 | -0.0257315 |
| TUBA1B | tubulin, alpha 1b | -0.0251505 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0250729 |
| RPS20 | ribosomal protein S20 | -0.0247549 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0247524 |
| RPS8 | ribosomal protein S8 | -0.0246941 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0245812 |
| CAVIN1 | caveolae associated protein 1 | -0.0245709 |
