| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tazarotene_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0725506 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.070205 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0600562 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0576911 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0529958 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.052959 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0523555 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0515217 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0461914 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0439153 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0435237 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0434897 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.043218 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0428081 |
| PTK2 | protein tyrosine kinase 2 | 0.042775 |
| NDRG1 | N-myc downstream regulated 1 | 0.0420414 |
| COG5 | component of oligomeric golgi complex 5 | 0.0415015 |
| TOP1 | topoisomerase (DNA) I | 0.0411148 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0409385 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0408573 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0399106 |
| ENO1 | enolase 1, (alpha) | 0.0396097 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0395467 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0393845 |
| TXNRD1 | thioredoxin reductase 1 | 0.0387873 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0387076 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0380131 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0363376 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0362923 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0361984 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0356952 |
| GPC6 | glypican 6 | 0.0355388 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0349675 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0348225 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0345113 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0344386 |
| FNBP1L | formin binding protein 1-like | 0.0342834 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0338991 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.033271 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0328344 |
| TPD52 | tumor protein D52 | 0.0326432 |
| RPL23 | ribosomal protein L23 | 0.0325988 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0320918 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0320307 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0318442 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0318275 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0313102 |
| SLMAP | sarcolemma associated protein | 0.0307517 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0304998 |
| PTGES2 | prostaglandin E synthase 2 | 0.0303611 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0300108 |
| TMF1 | TATA element modulatory factor 1 | 0.0297491 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0297239 |
| RPL5 | ribosomal protein L5 | 0.0296915 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0296047 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0295567 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0295232 |
| ZNF292 | zinc finger protein 292 | 0.02942 |
| RPS16 | ribosomal protein S16 | 0.0293277 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0290657 |
| RAD51B | RAD51 paralog B | 0.0287194 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0287079 |
| RNF149 | ring finger protein 149 | 0.0285052 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0284605 |
| MT2A | metallothionein 2A | 0.0281401 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0279188 |
| SLK | STE20-like kinase | 0.027904 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0278867 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0278747 |
| TMSB10 | thymosin beta 10 | 0.0276649 |
| NBAS | neuroblastoma amplified sequence | 0.0276306 |
| PDS5B | PDS5 cohesin associated factor B | 0.0275663 |
| HMGA1 | high mobility group AT-hook 1 | 0.027465 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0274563 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0273532 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0273526 |
| RPL15 | ribosomal protein L15 | 0.0272019 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0271634 |
| S100P | S100 calcium binding protein P | 0.0271589 |
| DST | dystonin | 0.0271584 |
| MYOF | myoferlin | 0.0271583 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.0271417 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0269204 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0268151 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0265476 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.026266 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0261711 |
| SERF2 | small EDRK-rich factor 2 | 0.0259577 |
| XPO1 | exportin 1 | 0.0258975 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0258769 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0257261 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0256588 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0255617 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0255592 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0253628 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.025032 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0250156 |
| CUL3 | cullin 3 | 0.0249967 |
| FTL | ferritin, light polypeptide | 0.0249658 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.0249586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.188094 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.147561 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.128348 |
| COL6A3 | collagen, type VI, alpha 3 | -0.109946 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.108378 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.099965 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0882267 |
| MMP1 | matrix metallopeptidase 1 | -0.0820216 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0786949 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0784277 |
| AHNAK | AHNAK nucleoprotein | -0.0741293 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0740922 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0738781 |
| MYO1E | myosin IE | -0.0718477 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0694108 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0682482 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0677739 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0662312 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0601145 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0583634 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0580342 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0556639 |
| INTS6 | integrator complex subunit 6 | -0.055601 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0554817 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0549954 |
| ASPH | aspartate beta-hydroxylase | -0.0541904 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0537339 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0535691 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0529214 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.051432 |
| RBM47 | RNA binding motif protein 47 | -0.050744 |
| PARD3 | par-3 family cell polarity regulator | -0.0493828 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0489429 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.048921 |
| PRKCA | protein kinase C, alpha | -0.0486819 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0483745 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0472545 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0467683 |
| CD44 | CD44 molecule (Indian blood group) | -0.0464313 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0459075 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0457172 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0454729 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0453713 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0450777 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0449434 |
| HOMER1 | homer scaffolding protein 1 | -0.0442381 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0440665 |
| HMGA2 | high mobility group AT-hook 2 | -0.0436156 |
| LAMC2 | laminin, gamma 2 | -0.0430931 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0428853 |
| FRMD5 | FERM domain containing 5 | -0.0427459 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0421819 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0418957 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0416365 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0407263 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0406782 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0404739 |
| MXD1 | MAX dimerization protein 1 | -0.0389731 |
| HPCAL1 | hippocalcin-like 1 | -0.0369603 |
| CA12 | carbonic anhydrase XII | -0.0368263 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0367927 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0367457 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0364264 |
| C1D | C1D nuclear receptor corepressor | -0.0359305 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0356028 |
| ACTG1 | actin gamma 1 | -0.0354394 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0350858 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.034363 |
| NABP1 | nucleic acid binding protein 1 | -0.0341476 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0340491 |
| HLA-B | major histocompatibility complex, class I, B | -0.0335002 |
| COL5A1 | collagen, type V, alpha 1 | -0.0334123 |
| EFNA5 | ephrin-A5 | -0.03338 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0326654 |
| GRAMD1B | GRAM domain containing 1B | -0.0323509 |
| CD9 | CD9 molecule | -0.0313296 |
| SMAD3 | SMAD family member 3 | -0.031218 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0310751 |
| ATOSA | atos homolog A | -0.0303955 |
| PLEC | plectin | -0.0303778 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0302983 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0302703 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0301308 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0300994 |
| EHBP1 | EH domain binding protein 1 | -0.0295029 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0294113 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0292941 |
| GLIS3 | GLIS family zinc finger 3 | -0.0292808 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0291484 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.028983 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0287855 |
| RLIM | ring finger protein, LIM domain interacting | -0.0286794 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0286138 |
| DIAPH2 | diaphanous-related formin 2 | -0.0285252 |
| TCP11L2 | t-complex 11, testis-specific-like 2 | -0.0284548 |
| CLMP | CXADR-like membrane protein | -0.0278935 |
| EMP1 | epithelial membrane protein 1 | -0.0278331 |
| WASF2 | WAS protein family, member 2 | -0.0276843 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0275238 |
| NUP98 | nucleoporin 98kDa | -0.0273073 |
