| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.120725 |
| FN1 | fibronectin 1 | 0.0735092 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0570299 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0511862 |
| VIM | vimentin | 0.0318812 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0285105 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0244501 |
| TMSB10 | thymosin beta 10 | 0.0226428 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0202375 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0195389 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.019097 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0185799 |
| HLA-B | major histocompatibility complex, class I, B | 0.01826 |
| CDH13 | cadherin 13 | 0.0174367 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0164812 |
| EGR1 | early growth response 1 | 0.0151008 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0140966 |
| PCBP1 | poly(rC) binding protein 1 | 0.0135866 |
| KIAA0825 | KIAA0825 | 0.0132886 |
| NCKAP5 | NCK-associated protein 5 | 0.0127524 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0126926 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0126872 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0126382 |
| DNER | delta/notch-like EGF repeat containing | 0.0121773 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0119058 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.011845 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0118172 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0117535 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0116301 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.011531 |
| STC1 | stanniocalcin 1 | 0.0112659 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0111548 |
| PRSS23 | protease, serine, 23 | 0.0111337 |
| RPL35A | ribosomal protein L35a | 0.0109263 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0108043 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.0106501 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0106085 |
| HMGA2 | high mobility group AT-hook 2 | 0.0103486 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0102002 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.00995077 |
| RIGI | RNA sensor RIG-I | 0.00984571 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00948328 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00941399 |
| IGF2 | insulin-like growth factor 2 | 0.00919505 |
| INHBA | inhibin, beta A | 0.00915821 |
| NEFL | neurofilament, light polypeptide | 0.0090268 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00863888 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00825926 |
| IL6 | interleukin 6 | 0.00802139 |
| HLA-A | major histocompatibility complex, class I, A | 0.00797713 |
| RHOB | ras homolog family member B | 0.00789326 |
| LSAMP | limbic system-associated membrane protein | 0.00778588 |
| PFN1 | profilin 1 | 0.00774368 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00771372 |
| CUX1 | cut-like homeobox 1 | 0.00770289 |
| SLC16A6 | solute carrier family 16, member 6 | 0.00768237 |
| PCDH9 | protocadherin 9 | 0.00756278 |
| NTN4 | netrin 4 | 0.0075387 |
| FAM107B | family with sequence similarity 107, member B | 0.00734408 |
| ZFHX3 | zinc finger homeobox 3 | 0.00725483 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.00724726 |
| RAD51B | RAD51 paralog B | 0.00716125 |
| HDAC9 | histone deacetylase 9 | 0.00714199 |
| SVIL | supervillin | 0.00704654 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00698664 |
| GANAB | glucosidase, alpha; neutral AB | 0.00694149 |
| STEAP1B | STEAP family member 1B | 0.00691054 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.00689191 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00683237 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00664641 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00663934 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00654781 |
| S100A6 | S100 calcium binding protein A6 | 0.00654348 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 0.0063429 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.00624283 |
| FST | follistatin | 0.00623775 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.00618759 |
| RAB31 | RAB31, member RAS oncogene family | 0.00617162 |
| HMGA1 | high mobility group AT-hook 1 | 0.00612326 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.00611773 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00606041 |
| PCDH15 | protocadherin-related 15 | 0.00603697 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00602666 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00597276 |
| RAB5B | RAB5B, member RAS oncogene family | 0.00597021 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.00587789 |
| C1D | C1D nuclear receptor corepressor | 0.00586213 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0057919 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.00575954 |
| NXPH4 | neurexophilin 4 | 0.00574189 |
| PAPPA2 | pappalysin 2 | 0.00563727 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.00554944 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00552556 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.00542272 |
| TNRC6C | trinucleotide repeat containing 6C | 0.00539255 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | 0.00539149 |
| FSTL4 | follistatin-like 4 | 0.00537887 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.00534269 |
| RBM47 | RNA binding motif protein 47 | 0.00533185 |
| GPRIN3 | GPRIN family member 3 | 0.00521324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.136577 |
| ASPH | aspartate beta-hydroxylase | -0.136313 |
| TXNRD1 | thioredoxin reductase 1 | -0.132613 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114912 |
| EFNA5 | ephrin-A5 | -0.110897 |
| GRAMD1B | GRAM domain containing 1B | -0.10922 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.108758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105454 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0906202 |
| PDE10A | phosphodiesterase 10A | -0.0854469 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.085176 |
| GDA | guanine deaminase | -0.0760212 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0759547 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0699713 |
| MYOF | myoferlin | -0.0662653 |
| NEK7 | NIMA-related kinase 7 | -0.0644857 |
| RTN4 | reticulon 4 | -0.0634281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0594682 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0592863 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0587851 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0568094 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0544594 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0539751 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0538274 |
| RPS2 | ribosomal protein S2 | -0.0526248 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0498178 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0485387 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0475747 |
| KYNU | kynureninase | -0.045043 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0443456 |
| TNPO1 | transportin 1 | -0.0437988 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0434953 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0430938 |
| RGS2 | regulator of G-protein signaling 2 | -0.0430913 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0428426 |
| NRCAM | neuronal cell adhesion molecule | -0.0423843 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0414187 |
| FLNB | filamin B, beta | -0.0414137 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0410853 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0406622 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0404709 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0396145 |
| MCL1 | myeloid cell leukemia 1 | -0.0395197 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0383013 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0378597 |
| MFF | mitochondrial fission factor | -0.0357518 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0353175 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0349201 |
| CANX | calnexin | -0.0344765 |
| RBM39 | RNA binding motif protein 39 | -0.0342756 |
| PGK1 | phosphoglycerate kinase 1 | -0.0342583 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0331039 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0327914 |
| CLTC | clathrin, heavy chain (Hc) | -0.0326187 |
| PTGR1 | prostaglandin reductase 1 | -0.0323626 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0320823 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0318419 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0318318 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0317271 |
| CTSC | cathepsin C | -0.0316565 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0316072 |
| PLCB4 | phospholipase C, beta 4 | -0.0314682 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0313887 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0312495 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0310967 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0307862 |
| ENAH | enabled homolog (Drosophila) | -0.0305609 |
| USP34 | ubiquitin specific peptidase 34 | -0.0304399 |
| EZR | ezrin | -0.0301968 |
| SRGN | serglycin | -0.0299994 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0299127 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0296983 |
| RPS6 | ribosomal protein S6 | -0.0296282 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0294839 |
| CENPF | centromere protein F, 350/400kDa | -0.0293868 |
| RAB3B | RAB3B, member RAS oncogene family | -0.0292923 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0292736 |
| TPR | translocated promoter region, nuclear basket protein | -0.0289254 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0289192 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0287892 |
| DST | dystonin | -0.0285527 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0285013 |
| SPAG9 | sperm associated antigen 9 | -0.0284984 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0284343 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0283014 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0282188 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0281346 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0280694 |
| UBC | ubiquitin C | -0.0280587 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0279635 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.027832 |
| SFPQ | splicing factor proline/glutamine-rich | -0.027729 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0275216 |
| ANXA1 | annexin A1 | -0.0273631 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.027189 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0271623 |
| TPM3 | tropomyosin 3 | -0.0271358 |
| MATR3 | matrin 3 | -0.0270483 |
| XPO1 | exportin 1 | -0.0270305 |
| FTL | ferritin, light polypeptide | -0.0270094 |
