| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.124172 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.091649 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0848568 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0813834 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0747824 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0734684 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0732713 |
| NAV2 | neuron navigator 2 | 0.0692905 |
| JUN | jun proto-oncogene | 0.0643393 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0637705 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0623724 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0620697 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0612836 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0606677 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.060026 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0593584 |
| ZNF292 | zinc finger protein 292 | 0.0589595 |
| XPO1 | exportin 1 | 0.0582265 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0565594 |
| RPL23 | ribosomal protein L23 | 0.0561211 |
| SPAG9 | sperm associated antigen 9 | 0.055493 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0550417 |
| RNF145 | ring finger protein 145 | 0.0547748 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.0546075 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0541855 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0537531 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0532937 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0529748 |
| JAK1 | Janus kinase 1 | 0.052506 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0517036 |
| EGR1 | early growth response 1 | 0.0515488 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0505746 |
| CDK6 | cyclin-dependent kinase 6 | 0.0505439 |
| CUL3 | cullin 3 | 0.0505265 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.050389 |
| METTL15 | methyltransferase like 15 | 0.0503214 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0485271 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0470603 |
| ANXA2 | annexin A2 | 0.046378 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.046303 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0462992 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0460829 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0452624 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0450926 |
| EZR | ezrin | 0.0450188 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0450124 |
| RTN4 | reticulon 4 | 0.0449211 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0437341 |
| TPD52 | tumor protein D52 | 0.0431639 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0425472 |
| GNAS | GNAS complex locus | 0.0400558 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0395027 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0388297 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0388279 |
| QKI | QKI, KH domain containing, RNA binding | 0.0383558 |
| USP15 | ubiquitin specific peptidase 15 | 0.0380395 |
| EMP1 | epithelial membrane protein 1 | 0.0376233 |
| EGFR | epidermal growth factor receptor | 0.037415 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0364412 |
| SMAD3 | SMAD family member 3 | 0.0355786 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0353136 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0350398 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0349639 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0346541 |
| CDC73 | cell division cycle 73 | 0.0343816 |
| MCL1 | myeloid cell leukemia 1 | 0.0343309 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.03409 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0338785 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.0329626 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0326625 |
| SRP54 | signal recognition particle 54kDa | 0.0324464 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0324425 |
| SFTPA2 | surfactant protein A2 | 0.0319048 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0317727 |
| ATXN1 | ataxin 1 | 0.0317643 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0317604 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0310214 |
| FTL | ferritin, light polypeptide | 0.0306502 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0304606 |
| RPL32 | ribosomal protein L32 | 0.0301014 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0296419 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.02964 |
| HDLBP | high density lipoprotein binding protein | 0.0292258 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0291039 |
| CNKSR3 | CNKSR family member 3 | 0.0289837 |
| RPL11 | ribosomal protein L11 | 0.0287319 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0283763 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0283572 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0278078 |
| RPL35A | ribosomal protein L35a | 0.027495 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0272367 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0271333 |
| ZNF148 | zinc finger protein 148 | 0.0270832 |
| PTMA | prothymosin, alpha | 0.0264086 |
| RBM25 | RNA binding motif protein 25 | 0.0258783 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0257506 |
| GLG1 | golgi glycoprotein 1 | 0.0253851 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0252058 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0247815 |
| SCFD1 | sec1 family domain containing 1 | 0.0242623 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.146988 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.111968 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.105713 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.104946 |
| ASPH | aspartate beta-hydroxylase | -0.0876128 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0861639 |
| PDE10A | phosphodiesterase 10A | -0.0741029 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0707936 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0704144 |
| GPC6 | glypican 6 | -0.0683482 |
| HELZ | helicase with zinc finger | -0.067994 |
| NDRG1 | N-myc downstream regulated 1 | -0.0665521 |
| EFNA5 | ephrin-A5 | -0.0623312 |
| SETD5 | SET domain containing 5 | -0.061335 |
| ACTG1 | actin gamma 1 | -0.059343 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0589037 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0586641 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0582116 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.056002 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0555366 |
| PRKCA | protein kinase C, alpha | -0.0548064 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0541326 |
| VMP1 | vacuole membrane protein 1 | -0.0511251 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0504382 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0469526 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0456645 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0455518 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0453242 |
| ZNF609 | zinc finger protein 609 | -0.0449669 |
| DTNA | dystrobrevin, alpha | -0.0435355 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0432378 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0429878 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0428936 |
| DIAPH2 | diaphanous-related formin 2 | -0.0428231 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.042196 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0421622 |
| RAD51B | RAD51 paralog B | -0.041965 |
| ITSN2 | intersectin 2 | -0.0403662 |
| NCOR1 | nuclear receptor corepressor 1 | -0.040219 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0398798 |
| PCM1 | pericentriolar material 1 | -0.0393921 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0390301 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0384095 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0382069 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0381114 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0379503 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0377482 |
| VIM | vimentin | -0.0374116 |
| NF1 | neurofibromin 1 | -0.0371534 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0354179 |
| ATP11A | ATPase, class VI, type 11A | -0.0350148 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0344145 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0340609 |
| MORF4L2 | mortality factor 4 like 2 | -0.033083 |
| CFDP1 | craniofacial development protein 1 | -0.032351 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.032216 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0320157 |
| MED13L | mediator complex subunit 13-like | -0.0313874 |
| POTEF | POTE ankyrin domain family, member F | -0.0313636 |
| TCF12 | transcription factor 12 | -0.0307132 |
| BBX | bobby sox homolog (Drosophila) | -0.0306327 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0298782 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0294441 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0291873 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0288169 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0286936 |
| RBM39 | RNA binding motif protein 39 | -0.0285839 |
| RORA | RAR-related orphan receptor A | -0.0282165 |
| AHNAK | AHNAK nucleoprotein | -0.02813 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0280956 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0278711 |
| FAT1 | FAT atypical cadherin 1 | -0.0278471 |
| SMYD3 | SET and MYND domain containing 3 | -0.0277633 |
| SBF2 | SET binding factor 2 | -0.0275459 |
| RAB6A | RAB6A, member RAS oncogene family | -0.026942 |
| TXNRD1 | thioredoxin reductase 1 | -0.026744 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0252611 |
| RHOA | ras homolog family member A | -0.025245 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0252371 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0248722 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0243787 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0242875 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0242025 |
| MAP4 | microtubule-associated protein 4 | -0.0241588 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0237772 |
| MYOF | myoferlin | -0.0234236 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0233012 |
| ATP13A3 | ATPase type 13A3 | -0.0227406 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0226946 |
| PTK2 | protein tyrosine kinase 2 | -0.0221881 |
| FMNL2 | formin-like 2 | -0.0218378 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0207838 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0205931 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0201877 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0199674 |
| YEATS2 | YEATS domain containing 2 | -0.0198427 |
| MED13 | mediator complex subunit 13 | -0.0196579 |
| SETX | senataxin | -0.0194888 |
| CD2AP | CD2-associated protein | -0.0191506 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0188572 |
