| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.130306 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.103359 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0857417 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0791152 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0768884 |
| FOXP1 | forkhead box P1 | 0.0748287 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0663454 |
| EGFR | epidermal growth factor receptor | 0.0580985 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0567344 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0560978 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0558654 |
| VCL | vinculin | 0.0539431 |
| NBEA | neurobeachin | 0.0505511 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0490254 |
| NFIA | nuclear factor I/A | 0.0485258 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0353566 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0345677 |
| ACTG1 | actin gamma 1 | 0.0345517 |
| EFNA5 | ephrin-A5 | 0.0335049 |
| HDAC9 | histone deacetylase 9 | 0.0326545 |
| ECT2 | epithelial cell transforming 2 | 0.0319132 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0317873 |
| TRERF1 | transcriptional regulating factor 1 | 0.0285623 |
| GLI3 | GLI family zinc finger 3 | 0.0282277 |
| DIAPH2 | diaphanous-related formin 2 | 0.0279648 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0275491 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0262207 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0261796 |
| GNAS | GNAS complex locus | 0.0257863 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0256145 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0255063 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.025459 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0251779 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0233407 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0226212 |
| RHBDD1 | rhomboid domain containing 1 | 0.0220053 |
| RPLP0 | ribosomal protein, large, P0 | 0.0219429 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0218994 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0218385 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0211382 |
| HMGA1 | high mobility group AT-hook 1 | 0.0211132 |
| NEBL | nebulette | 0.0205644 |
| ARF1 | ADP-ribosylation factor 1 | 0.0202968 |
| FLNB | filamin B, beta | 0.0201604 |
| PDE7B | phosphodiesterase 7B | 0.0201053 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.019915 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0192293 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0189785 |
| ZNF438 | zinc finger protein 438 | 0.0185527 |
| LDHA | lactate dehydrogenase A | 0.0183878 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0183867 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0183856 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0182126 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0180969 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.018087 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0179349 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0177838 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0177365 |
| CAVIN2 | caveolae associated protein 2 | 0.0170472 |
| RPL12 | ribosomal protein L12 | 0.0168114 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0165799 |
| CALR | calreticulin | 0.0164208 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0162627 |
| RACK1 | receptor for activated C kinase 1 | 0.0161248 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.0161212 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0160378 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0159208 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0158848 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0155807 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.015487 |
| TPTE | transmembrane phosphatase with tensin homology | 0.0151299 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0148874 |
| HLA-B | major histocompatibility complex, class I, B | 0.0148396 |
| TMEM131 | transmembrane protein 131 | 0.0147723 |
| RAB14 | RAB14, member RAS oncogene family | 0.0145859 |
| MT2A | metallothionein 2A | 0.0145818 |
| MEIS2 | Meis homeobox 2 | 0.0145579 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0145097 |
| MTAP | methylthioadenosine phosphorylase | 0.0144973 |
| CMIP | c-Maf inducing protein | 0.0143179 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0142879 |
| S100A6 | S100 calcium binding protein A6 | 0.0142324 |
| ACACA | acetyl-CoA carboxylase alpha | 0.014206 |
| LDHB | lactate dehydrogenase B | 0.0141367 |
| RAD51B | RAD51 paralog B | 0.0141164 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0140614 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.014013 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0140073 |
| WDR43 | WD repeat domain 43 | 0.0139994 |
| PCBP1 | poly(rC) binding protein 1 | 0.0139151 |
| FASN | fatty acid synthase | 0.0137224 |
| VMP1 | vacuole membrane protein 1 | 0.0136635 |
| USP36 | ubiquitin specific peptidase 36 | 0.0135568 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.013536 |
| RPL13A | ribosomal protein L13a | 0.013464 |
| HDLBP | high density lipoprotein binding protein | 0.0134602 |
| UCK2 | uridine-cytidine kinase 2 | 0.0134388 |
| ATP11A | ATPase, class VI, type 11A | 0.0131936 |
| PARD3 | par-3 family cell polarity regulator | 0.0131921 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.0131266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.101461 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.08827 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0807608 |
| RPS2 | ribosomal protein S2 | -0.072827 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0688827 |
| PTMA | prothymosin, alpha | -0.0657946 |
| PKM | pyruvate kinase, muscle | -0.0533773 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0529797 |
| EZR | ezrin | -0.0491638 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0484572 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0481373 |
| MKI67 | marker of proliferation Ki-67 | -0.0472046 |
| RPL3 | ribosomal protein L3 | -0.0463503 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0449214 |
| CENPF | centromere protein F, 350/400kDa | -0.0426867 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0416463 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0400547 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0393476 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0388728 |
| AHNAK | AHNAK nucleoprotein | -0.0385667 |
| BRD2 | bromodomain containing 2 | -0.0368495 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0356746 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0347746 |
| UBC | ubiquitin C | -0.0345586 |
| ANXA1 | annexin A1 | -0.0344266 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0343379 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0330385 |
| POTEF | POTE ankyrin domain family, member F | -0.0327874 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0327249 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0321322 |
| XPO1 | exportin 1 | -0.0317878 |
| GOLGA4 | golgin A4 | -0.0311051 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0308795 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0308406 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0303933 |
| B2M | beta-2-microglobulin | -0.0300404 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0296389 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0294437 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0292423 |
| NCKAP1 | NCK-associated protein 1 | -0.0288694 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0287142 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0282384 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0280835 |
| FAM13A | family with sequence similarity 13, member A | -0.0280139 |
| ZNF292 | zinc finger protein 292 | -0.0276312 |
| USP34 | ubiquitin specific peptidase 34 | -0.0274213 |
| RPS3 | ribosomal protein S3 | -0.0273447 |
| SETD5 | SET domain containing 5 | -0.0270506 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0269572 |
| PHIP | pleckstrin homology domain interacting protein | -0.0268958 |
| RTN4 | reticulon 4 | -0.0264408 |
| BMP10 | bone morphogenetic protein 10 | -0.0258818 |
| NBAS | neuroblastoma amplified sequence | -0.0257937 |
| MACROD2 | MACRO domain containing 2 | -0.0254291 |
| RCOR1 | REST corepressor 1 | -0.0252591 |
| RPS12 | ribosomal protein S12 | -0.0251125 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0249972 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0249557 |
| JMJD1C | jumonji domain containing 1C | -0.0248508 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0245562 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0244746 |
| H1-4 | H1.4 linker histone, cluster member | -0.0243927 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0241397 |
| TAOK1 | TAO kinase 1 | -0.02373 |
| RPS18 | ribosomal protein S18 | -0.0234098 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0233272 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0232696 |
| USP47 | ubiquitin specific peptidase 47 | -0.0228624 |
| BRD4 | bromodomain containing 4 | -0.0223994 |
| PGK1 | phosphoglycerate kinase 1 | -0.022133 |
| TMF1 | TATA element modulatory factor 1 | -0.0221082 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0218466 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.021583 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0215092 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0215087 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0215005 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0214643 |
| TXNIP | thioredoxin interacting protein | -0.0214129 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0213996 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.021347 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0213231 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0212741 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.021268 |
| PDE8A | phosphodiesterase 8A | -0.0212653 |
| DIAPH3 | diaphanous-related formin 3 | -0.0209695 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.020912 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0208654 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0208463 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0207994 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0206267 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0205973 |
| SPAG9 | sperm associated antigen 9 | -0.0205536 |
| PRKCI | protein kinase C, iota | -0.0204588 |
| RPS8 | ribosomal protein S8 | -0.0204032 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0203922 |
| RPL21 | ribosomal protein L21 | -0.0203662 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.020253 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0201991 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0201511 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.020072 |
