| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0370775 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0289798 |
| EGFR | epidermal growth factor receptor | 0.0286983 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0228271 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0223665 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0191498 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0185915 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0185102 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0180167 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0178081 |
| EFNA5 | ephrin-A5 | 0.0174179 |
| SYNPO | synaptopodin | 0.0173421 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0164687 |
| SEC24A | SEC24 family member A | 0.0164509 |
| NAV2 | neuron navigator 2 | 0.0163023 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0162557 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0159309 |
| CAPRIN2 | caprin family member 2 | 0.0157983 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.015533 |
| USP24 | ubiquitin specific peptidase 24 | 0.0155131 |
| MMP12 | matrix metallopeptidase 12 | 0.0155051 |
| NOTCH2 | notch 2 | 0.0154987 |
| RIN2 | Ras and Rab interactor 2 | 0.0152689 |
| ZNF133 | zinc finger protein 133 | 0.0151557 |
| RNF145 | ring finger protein 145 | 0.0150353 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0149475 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0148147 |
| HDAC9 | histone deacetylase 9 | 0.0147128 |
| FMNL2 | formin-like 2 | 0.0146309 |
| EFL1 | elongation factor like GTPase 1 | 0.0144991 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0143904 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0143771 |
| EGR1 | early growth response 1 | 0.0143497 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0141211 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0140189 |
| SNX13 | sorting nexin 13 | 0.0140094 |
| GPR107 | G protein-coupled receptor 107 | 0.0139275 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0138838 |
| BIN3 | bridging integrator 3 | 0.0138428 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0138371 |
| NRXN3 | neurexin 3 | 0.0138022 |
| FRMD5 | FERM domain containing 5 | 0.0137086 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0136949 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0136874 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.013645 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0135739 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0135589 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0135439 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0134716 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0132626 |
| IL15 | interleukin 15 | 0.0130754 |
| ITGB5 | integrin, beta 5 | 0.0130238 |
| FAF2 | Fas associated factor family member 2 | 0.0130066 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0129263 |
| ATP13A3 | ATPase type 13A3 | 0.0128842 |
| TNPO3 | transportin 3 | 0.0128725 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0128033 |
| SETX | senataxin | 0.0127643 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0127357 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0126608 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0125542 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0125228 |
| PGM1 | phosphoglucomutase 1 | 0.0123986 |
| ZNF331 | zinc finger protein 331 | 0.012375 |
| WDR1 | WD repeat domain 1 | 0.0123602 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0123443 |
| FRMD4A | FERM domain containing 4A | 0.0122906 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0122416 |
| SMAD2 | SMAD family member 2 | 0.0122224 |
| SPOPL | speckle-type POZ protein-like | 0.0121889 |
| RBAK-RBAKDN | RBAK-RBAKDN readthrough | 0.0121758 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.012137 |
| ZNF146 | zinc finger protein 146 | 0.0121224 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0121114 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0120617 |
| FRMD6 | FERM domain containing 6 | 0.0120466 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.012009 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0119555 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.011954 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0118351 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.0118154 |
| MSN | moesin | 0.0117949 |
| NBAS | neuroblastoma amplified sequence | 0.0117237 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0117098 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0116566 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0116468 |
| CRLS1 | cardiolipin synthase 1 | 0.0116401 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.011627 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0116039 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0115995 |
| TENT5C | terminal nucleotidyltransferase 5C | 0.0115865 |
| CEP120 | centrosomal protein 120kDa | 0.0115741 |
| DSPP | dentin sialophosphoprotein | 0.0114486 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.011447 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.011412 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.011374 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0113494 |
| ZMYM6 | zinc finger, MYM-type 6 | 0.0113337 |
| GTPBP1 | GTP binding protein 1 | 0.0112825 |
| MYO19 | myosin XIX | 0.0112614 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.364962 |
| TMSB10 | thymosin beta 10 | -0.208754 |
| MT2A | metallothionein 2A | -0.176576 |
| VIM | vimentin | -0.17154 |
| B2M | beta-2-microglobulin | -0.129339 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.12231 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118367 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0950814 |
| HLA-B | major histocompatibility complex, class I, B | -0.0905509 |
| COL1A1 | collagen, type I, alpha 1 | -0.0856853 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0825719 |
| FN1 | fibronectin 1 | -0.0812728 |
| CALU | calumenin | -0.0793832 |
| UBC | ubiquitin C | -0.0790617 |
| COL1A2 | collagen, type I, alpha 2 | -0.0787303 |
| PTMA | prothymosin, alpha | -0.074361 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0678995 |
| CANX | calnexin | -0.0639594 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0636098 |
| ENO1 | enolase 1, (alpha) | -0.0612891 |
| LOXL2 | lysyl oxidase-like 2 | -0.0594273 |
| HLA-C | major histocompatibility complex, class I, C | -0.0581833 |
| POTEF | POTE ankyrin domain family, member F | -0.0562195 |
| MAP1B | microtubule-associated protein 1B | -0.0558359 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0558208 |
| FTL | ferritin, light polypeptide | -0.0555333 |
| AHNAK | AHNAK nucleoprotein | -0.0554096 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0548995 |
| HLA-A | major histocompatibility complex, class I, A | -0.05363 |
| PRSS23 | protease, serine, 23 | -0.053394 |
| SEPTIN7 | septin 7 | -0.0507106 |
| CCNI | cyclin I | -0.0498227 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0495751 |
| STC1 | stanniocalcin 1 | -0.0491221 |
| MT1X | metallothionein 1X | -0.0467824 |
| S100A10 | S100 calcium binding protein A10 | -0.0467167 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.046124 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0454656 |
| SDC4 | syndecan 4 | -0.0451556 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0450036 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0440314 |
| LDHA | lactate dehydrogenase A | -0.0423137 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413466 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0412798 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0410826 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0393353 |
| CD44 | CD44 molecule (Indian blood group) | -0.0391968 |
| HDLBP | high density lipoprotein binding protein | -0.0389846 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0371016 |
| TXNIP | thioredoxin interacting protein | -0.0367429 |
| CAVIN1 | caveolae associated protein 1 | -0.036392 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0362214 |
| RPL28 | ribosomal protein L28 | -0.0359402 |
| TPM4 | tropomyosin 4 | -0.0356823 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0354858 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0352084 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0351113 |
| LOC112694756 | uncharaterized LOC112694756 | -0.034746 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0347067 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0339275 |
| ANXA2 | annexin A2 | -0.0330075 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326723 |
| PKM | pyruvate kinase, muscle | -0.0325024 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0321347 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0321024 |
| RPS8 | ribosomal protein S8 | -0.0312519 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0308926 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0303351 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299497 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0296248 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0295352 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0292644 |
| FUS | FUS RNA binding protein | -0.0292296 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0290431 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0284242 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0282229 |
| ACTG1 | actin gamma 1 | -0.0277908 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0275961 |
| BSG | basigin (Ok blood group) | -0.0273745 |
| H3-3B | H3.3 histone B | -0.0271841 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0268468 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0268319 |
| S100A9 | S100 calcium binding protein A9 | -0.0267578 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0265376 |
| RHEB | Ras homolog enriched in brain | -0.026011 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0258471 |
| OGA | O-GlcNAcase | -0.0256513 |
| HMGB1 | high mobility group box 1 | -0.0246719 |
| MTPN | myotrophin | -0.0245981 |
| COL5A2 | collagen, type V, alpha 2 | -0.0243785 |
| VCL | vinculin | -0.0243638 |
| TPM2 | tropomyosin 2 (beta) | -0.0241793 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0239011 |
| LOX | lysyl oxidase | -0.0238909 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0238125 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0237531 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.023597 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0235962 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.023538 |
| S100A6 | S100 calcium binding protein A6 | -0.0234607 |
