| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0416471 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0268837 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.024071 |
| PYGL | phosphorylase, glycogen, liver | 0.0214036 |
| KIF5B | kinesin family member 5B | 0.0198306 |
| ITGA6 | integrin, alpha 6 | 0.019407 |
| SNX14 | sorting nexin 14 | 0.0193777 |
| ANKRD37 | ankyrin repeat domain 37 | 0.018638 |
| IGF2 | insulin-like growth factor 2 | 0.0182425 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0179941 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0175425 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0174814 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.017467 |
| NGLY1 | N-glycanase 1 | 0.0174313 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0173416 |
| MYO10 | myosin X | 0.0167334 |
| PFN1 | profilin 1 | 0.0166379 |
| MAP1B | microtubule-associated protein 1B | 0.0163413 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0162198 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0161058 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158409 |
| SLMAP | sarcolemma associated protein | 0.0157333 |
| PAPOLA | poly(A) polymerase alpha | 0.0156136 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0155398 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0152939 |
| NUCB2 | nucleobindin 2 | 0.0152253 |
| FAM13A | family with sequence similarity 13, member A | 0.0151091 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0147393 |
| COG6 | component of oligomeric golgi complex 6 | 0.0146946 |
| PMM2 | phosphomannomutase 2 | 0.0146544 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0142799 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0141027 |
| HMGA1 | high mobility group AT-hook 1 | 0.0139668 |
| TPD52 | tumor protein D52 | 0.0139247 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0138774 |
| PCBP1 | poly(rC) binding protein 1 | 0.01372 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0137131 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0136788 |
| HDGF | hepatoma-derived growth factor | 0.0136371 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.013596 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0135849 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0135582 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0135394 |
| CAV2 | caveolin 2 | 0.0134581 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0134513 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0129455 |
| DTNA | dystrobrevin, alpha | 0.0128177 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0126162 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.012596 |
| USP37 | ubiquitin specific peptidase 37 | 0.0125941 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0125818 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0124961 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0123747 |
| ZNF451 | zinc finger protein 451 | 0.0123109 |
| GPC5 | glypican 5 | 0.0120529 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0119418 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0118958 |
| TMF1 | TATA element modulatory factor 1 | 0.0118448 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0118404 |
| RPL21 | ribosomal protein L21 | 0.0117449 |
| OSBPL6 | oxysterol binding protein-like 6 | 0.0116776 |
| NOTCH2 | notch 2 | 0.0116656 |
| ATF4 | activating transcription factor 4 | 0.011477 |
| CD9 | CD9 molecule | 0.0114339 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0114263 |
| ZNF277 | zinc finger protein 277 | 0.0114034 |
| EXOC5 | exocyst complex component 5 | 0.0113391 |
| INSIG1 | insulin induced gene 1 | 0.0113243 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0112503 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0111776 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0111609 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0110957 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0110898 |
| TFG | TRK-fused gene | 0.0110801 |
| COL5A1 | collagen, type V, alpha 1 | 0.0110046 |
| DCP1A | decapping mRNA 1A | 0.0109986 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0109982 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0109847 |
| ARRDC3 | arrestin domain containing 3 | 0.0109784 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.01096 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0109369 |
| ECE1 | endothelin converting enzyme 1 | 0.0109282 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0109237 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0109055 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.010865 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.0108407 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0108235 |
| GOLGA2 | golgin A2 | 0.0107941 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0107577 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0107563 |
| PRKCA | protein kinase C, alpha | 0.0106858 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.010669 |
| NPHP3 | nephronophthisis 3 (adolescent) | 0.0106556 |
| ADSS2 | adenylosuccinate synthase 2 | 0.0106201 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.010612 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0105807 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0105787 |
| MARCHF5 | membrane associated ring-CH-type finger 5 | 0.0105673 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0105647 |
| FN1 | fibronectin 1 | 0.0105037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.303604 |
| VIM | vimentin | -0.0795303 |
| OSMR | oncostatin M receptor | -0.0774991 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0748725 |
| SMYD3 | SET and MYND domain containing 3 | -0.0712279 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0560392 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0469155 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0467943 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0454849 |
| DIAPH3 | diaphanous-related formin 3 | -0.045251 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0444201 |
| TMSB10 | thymosin beta 10 | -0.0439404 |
| VCL | vinculin | -0.0438733 |
| RBM39 | RNA binding motif protein 39 | -0.0435803 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0423375 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0418645 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0415494 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0413837 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0412503 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0412042 |
| DST | dystonin | -0.0400831 |
| YBX3 | Y box binding protein 3 | -0.0394869 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0391639 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0386767 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.037827 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.037494 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0372986 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0366377 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0359112 |
| AHNAK | AHNAK nucleoprotein | -0.0348771 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0348472 |
| FMN1 | formin 1 | -0.0344676 |
| USP34 | ubiquitin specific peptidase 34 | -0.0343101 |
| ACTG1 | actin gamma 1 | -0.0341999 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0337575 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.033723 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0335083 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0334528 |
| NF1 | neurofibromin 1 | -0.0330045 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0329923 |
| PHF14 | PHD finger protein 14 | -0.0323798 |
| NALCN | sodium leak channel, non selective | -0.032044 |
| CD44 | CD44 molecule (Indian blood group) | -0.0318043 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0316569 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0313119 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0305214 |
| GOLGA4 | golgin A4 | -0.0304416 |
| ANXA2 | annexin A2 | -0.0301368 |
| YAP1 | Yes-associated protein 1 | -0.0297585 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0295935 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0295379 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0294824 |
| SLC38A2 | solute carrier family 38, member 2 | -0.028528 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0282928 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0281651 |
| ATM | ATM serine/threonine kinase | -0.0279295 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0278208 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0277822 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.027745 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0275915 |
| EXOC6B | exocyst complex component 6B | -0.0273613 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0272475 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0272282 |
| ERBIN | erbb2 interacting protein | -0.0263305 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0261055 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0259514 |
| GPC6 | glypican 6 | -0.0258111 |
| NCOR1 | nuclear receptor corepressor 1 | -0.025799 |
| DEK | DEK proto-oncogene | -0.0253572 |
| FNIP1 | folliculin interacting protein 1 | -0.0250662 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0249395 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0247902 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0245332 |
| GNAS | GNAS complex locus | -0.0245246 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0242495 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0241252 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0239571 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0238074 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0237693 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0235019 |
| CANX | calnexin | -0.0232704 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0232174 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0231248 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.023123 |
| TMEM263 | transmembrane protein 263 | -0.0229535 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0228911 |
| PDE8A | phosphodiesterase 8A | -0.022773 |
| RPL19 | ribosomal protein L19 | -0.0227322 |
| RTN4 | reticulon 4 | -0.0226911 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0226787 |
| NAV3 | neuron navigator 3 | -0.0224228 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0222953 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0221468 |
| KIAA1328 | KIAA1328 | -0.0221426 |
| NKTR | natural killer cell triggering receptor | -0.0221034 |
| RAD21 | RAD21 homolog (S. pombe) | -0.022099 |
| RANBP17 | RAN binding protein 17 | -0.0219066 |
| RIGI | RNA sensor RIG-I | -0.0218417 |
| RDX | radixin | -0.0218172 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0216916 |
