| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tazarotene perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tazarotene_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0389144 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0115115 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0106282 |
| TGM2 | transglutaminase 2 | 0.0103238 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00925671 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00904734 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00891315 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00889067 |
| FOSL1 | FOS-like antigen 1 | 0.00875185 |
| HMGB2 | high mobility group box 2 | 0.00836406 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00791696 |
| PCBP1 | poly(rC) binding protein 1 | 0.00719198 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.00676292 |
| EGR1 | early growth response 1 | 0.00662359 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.00640774 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.00629894 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.00618511 |
| TOM1 | target of myb1 (chicken) | 0.00618188 |
| IGF2 | insulin-like growth factor 2 | 0.00616053 |
| TUFT1 | tuftelin 1 | 0.00605934 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.00602972 |
| MED26 | mediator complex subunit 26 | 0.00601864 |
| NOCT | nocturnin | 0.00596596 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00576448 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00567439 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00566366 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00562868 |
| QKI | QKI, KH domain containing, RNA binding | 0.00556322 |
| FERMT2 | fermitin family member 2 | 0.00547036 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00544806 |
| RYBP | RING1 and YY1 binding protein | 0.00539952 |
| PRKCI | protein kinase C, iota | 0.00538849 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0053835 |
| PNN | pinin, desmosome associated protein | 0.00531227 |
| ANKRD33B | ankyrin repeat domain 33B | 0.00529429 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.00522177 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.00515676 |
| MXD1 | MAX dimerization protein 1 | 0.0050602 |
| HBS1L | HBS1-like translational GTPase | 0.00504654 |
| FOXJ3 | forkhead box J3 | 0.0048976 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.00489276 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.00485972 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.00476803 |
| RPL3 | ribosomal protein L3 | 0.00474781 |
| USP12 | ubiquitin specific peptidase 12 | 0.00473264 |
| RARA | retinoic acid receptor, alpha | 0.00467203 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.00464653 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00463761 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.00462351 |
| DCTN1 | dynactin 1 | 0.00461742 |
| ERI1 | exoribonuclease 1 | 0.00458856 |
| RAB8B | RAB8B, member RAS oncogene family | 0.00457644 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0045698 |
| ADM | adrenomedullin | 0.00455651 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00450877 |
| TSC22D4 | TSC22 domain family, member 4 | 0.00450515 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00447499 |
| RAB5B | RAB5B, member RAS oncogene family | 0.00445927 |
| HDAC3 | histone deacetylase 3 | 0.00444297 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.00441845 |
| MTMR2 | myotubularin related protein 2 | 0.00439041 |
| MXRA7 | matrix-remodelling associated 7 | 0.00430216 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | 0.00426927 |
| RPS18 | ribosomal protein S18 | 0.00426424 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00426156 |
| ERLIN1 | ER lipid raft associated 1 | 0.00419929 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | 0.00419879 |
| SNX3 | sorting nexin 3 | 0.00416445 |
| YAP1 | Yes-associated protein 1 | 0.00408949 |
| MED15 | mediator complex subunit 15 | 0.00407864 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.00403989 |
| OTUD6B | OTU domain containing 6B | 0.00403973 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00402291 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.00401454 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | 0.00401442 |
| LEMD3 | LEM domain containing 3 | 0.00400544 |
| CCDC126 | coiled-coil domain containing 126 | 0.00398639 |
| ARL6 | ADP-ribosylation factor-like 6 | 0.00397983 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.00397823 |
| CDK11B | cyclin-dependent kinase 11B | 0.00397519 |
| RPS2 | ribosomal protein S2 | 0.00397035 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00395615 |
| MYOCOS | myocilin opposite strand | 0.00395511 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 | 0.00395344 |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.00392917 |
| H1-4 | H1.4 linker histone, cluster member | 0.00388981 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.00387327 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.00386167 |
| SDC3 | syndecan 3 | 0.00385551 |
| CEP85L | centrosomal protein 85kDa-like | 0.00383626 |
| PER1 | period circadian clock 1 | 0.00382931 |
| LRRC1 | leucine rich repeat containing 1 | 0.00382863 |
| PLXNB2 | plexin B2 | 0.00381497 |
| TNPO3 | transportin 3 | 0.00381255 |
| RPS3A | ribosomal protein S3A | 0.00381097 |
| DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 0.00380381 |
| MOB3B | MOB kinase activator 3B | 0.00380093 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00378504 |
| CRY1 | cryptochrome circadian clock 1 | 0.00376463 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | 0.00376375 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.292997 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.251901 |
| FN1 | fibronectin 1 | -0.250894 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.195145 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.17281 |
| NRG1 | neuregulin 1 | -0.131855 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128545 |
| PTMA | prothymosin, alpha | -0.126638 |
| CANX | calnexin | -0.125243 |
| SQSTM1 | sequestosome 1 | -0.106759 |
| ITGA1 | integrin, alpha 1 | -0.089742 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0890744 |
| ASPH | aspartate beta-hydroxylase | -0.0855228 |
| HMGA2 | high mobility group AT-hook 2 | -0.0837739 |
| FTL | ferritin, light polypeptide | -0.0791807 |
| VIM | vimentin | -0.0741312 |
| TMSB10 | thymosin beta 10 | -0.0737092 |
| S100A6 | S100 calcium binding protein A6 | -0.0709605 |
| GLIS3 | GLIS family zinc finger 3 | -0.0659054 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0645277 |
| SYT1 | synaptotagmin I | -0.0582478 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0560209 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0559 |
| TMSB4X | thymosin beta 4, X-linked | -0.0555729 |
| SFTPA2 | surfactant protein A2 | -0.0536517 |
| PLIN2 | perilipin 2 | -0.0533242 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.052694 |
| B2M | beta-2-microglobulin | -0.0518056 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0508193 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0500651 |
| HLA-B | major histocompatibility complex, class I, B | -0.0494629 |
| AHR | aryl hydrocarbon receptor | -0.0493022 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0480962 |
| ENO1 | enolase 1, (alpha) | -0.0474508 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.046995 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0466626 |
| OSMR | oncostatin M receptor | -0.0463864 |
| TPR | translocated promoter region, nuclear basket protein | -0.0449048 |
| RAI14 | retinoic acid induced 14 | -0.0431772 |
| LMNA | lamin A/C | -0.041168 |
| TXNIP | thioredoxin interacting protein | -0.0406972 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0400524 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0397281 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0393358 |
| CALU | calumenin | -0.038789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0385614 |
| CD109 | CD109 molecule | -0.0384082 |
| TMEM165 | transmembrane protein 165 | -0.0380756 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0380692 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0379428 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0368553 |
| EFNA5 | ephrin-A5 | -0.0358773 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0355864 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0355355 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0354548 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0354433 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0352843 |
| ETV1 | ets variant 1 | -0.0349031 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0344017 |
| CALR | calreticulin | -0.0342013 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0338042 |
| S100A10 | S100 calcium binding protein A10 | -0.0337703 |
| NRP1 | neuropilin 1 | -0.0336247 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.033106 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0330826 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0328275 |
| CENPF | centromere protein F, 350/400kDa | -0.0327615 |
| TXNRD1 | thioredoxin reductase 1 | -0.0326225 |
| H1-0 | H1.0 linker histone | -0.0324185 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0323379 |
| KLHL5 | kelch-like family member 5 | -0.0320939 |
| RACK1 | receptor for activated C kinase 1 | -0.0318553 |
| DST | dystonin | -0.0318352 |
| HDLBP | high density lipoprotein binding protein | -0.0318005 |
| TMEM156 | transmembrane protein 156 | -0.0317348 |
| MTDH | metadherin | -0.0316357 |
| NDRG1 | N-myc downstream regulated 1 | -0.0316332 |
| USP34 | ubiquitin specific peptidase 34 | -0.0316052 |
| RPS6 | ribosomal protein S6 | -0.0315479 |
| ETV6 | ets variant 6 | -0.0315432 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0308789 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0306695 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0301019 |
| CEP350 | centrosomal protein 350kDa | -0.0300763 |
| AHNAK | AHNAK nucleoprotein | -0.0299889 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0299771 |
| PKM | pyruvate kinase, muscle | -0.0296376 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0294786 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0293273 |
| MT2A | metallothionein 2A | -0.0292564 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0290183 |
| RPS24 | ribosomal protein S24 | -0.0289955 |
| MAP1B | microtubule-associated protein 1B | -0.0289568 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0288144 |
| IER3 | immediate early response 3 | -0.0286559 |
| PGK1 | phosphoglycerate kinase 1 | -0.028451 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0283724 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0281657 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0281644 |
| RPL35A | ribosomal protein L35a | -0.028124 |
