| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/76453683 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Teijin compound 1 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.94 |
| TSPAN3 | tetraspanin 3 | 0.89 |
| CD63 | CD63 molecule | 0.8 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.71 |
| APOB | apolipoprotein B | 0.62 |
| ZNF219 | zinc finger protein 219 | 0.54 |
| ADGRE2 | adhesion G protein-coupled receptor E2 | 0.5 |
| SUCO | SUN domain containing ossification factor | 0.47 |
| MYH13 | myosin, heavy chain 13, skeletal muscle | 0.45 |
| VIM | vimentin | 0.43 |
| HKDC1 | hexokinase domain containing 1 | 0.43 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.41 |
| BHLHA15 | basic helix-loop-helix family, member a15 | 0.41 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.39 |
| MIS12 | MIS12 kinetochore complex component | 0.38 |
| RNF187 | ring finger protein 187 | 0.36 |
| BCORL1 | BCL6 corepressor-like 1 | 0.36 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | 0.36 |
| PLPP2 | phospholipid phosphatase 2 | 0.35 |
| IFNGR1 | interferon gamma receptor 1 | 0.34 |
| PAQR7 | progestin and adipoQ receptor family member VII | 0.34 |
| MYZAP | myocardial zonula adherens protein | 0.33 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.33 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.32 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.32 |
| PAH | phenylalanine hydroxylase | 0.32 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.31 |
| SCARB1 | scavenger receptor class B, member 1 | 0.31 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.31 |
| RNASET2 | ribonuclease T2 | 0.3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.3 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 0.3 |
| CHCHD2P9 | coiled-coil-helix-coiled-coil-helix domain containing 2 pseudogene 9 | 0.3 |
| KIAA1210 | KIAA1210 | 0.3 |
| MICOS10 | mitochondrial contact site and cristae organizing system subunit 10 | 0.3 |
| CEP68 | centrosomal protein 68kDa | 0.3 |
| IGSF8 | immunoglobulin superfamily, member 8 | 0.3 |
| UBE2J2 | ubiquitin-conjugating enzyme E2, J2 | 0.29 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.29 |
| UPP1 | uridine phosphorylase 1 | 0.29 |
| TMEM41B | transmembrane protein 41B | 0.29 |
| DDTL | D-dopachrome tautomerase-like | 0.29 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.29 |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 | 0.29 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.29 |
| NOTCH3 | notch 3 | 0.29 |
| CLOCK | clock circadian regulator | 0.29 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.29 |
| ZNF669 | zinc finger protein 669 | 0.29 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.28 |
| XIRP1 | xin actin binding repeat containing 1 | 0.28 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.28 |
| TMEM59 | transmembrane protein 59 | 0.28 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.28 |
| CCDC57 | coiled-coil domain containing 57 | 0.28 |
| LMTK2 | lemur tyrosine kinase 2 | 0.28 |
| NCOA4 | nuclear receptor coactivator 4 | 0.28 |
| RNF166 | ring finger protein 166 | 0.28 |
| CD274 | CD274 molecule | 0.27 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.27 |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) | 0.27 |
| TSPAN33 | tetraspanin 33 | 0.27 |
| NIBAN1 | niban apoptosis regulator 1 | 0.27 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.27 |
| GPATCH3 | G patch domain containing 3 | 0.27 |
| SLC35F6 | solute carrier family 35, member F6 | 0.27 |
| CTSA | cathepsin A | 0.27 |
| SDC1 | syndecan 1 | 0.27 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.27 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.27 |
| ATG10 | autophagy related 10 | 0.27 |
| KLF10 | Kruppel-like factor 10 | 0.27 |
| ING5 | inhibitor of growth family, member 5 | 0.26 |
| CERS4 | ceramide synthase 4 | 0.26 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | 0.26 |
| ARG2 | arginase 2 | 0.26 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.26 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.26 |
| TRIM9 | tripartite motif containing 9 | 0.25 |
| SLC39A11 | solute carrier family 39, member 11 | 0.25 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.25 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.25 |
| MSMO1 | methylsterol monooxygenase 1 | 0.25 |
| MPV17L2 | MPV17 mitochondrial membrane protein-like 2 | 0.25 |
| SELENOK | selenoprotein K | 0.25 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.25 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.25 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.25 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.24 |
| COPZ1 | coatomer protein complex, subunit zeta 1 | 0.24 |
| SGCE | sarcoglycan, epsilon | 0.24 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.24 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.24 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.24 |
| CD81 | CD81 molecule | 0.24 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 0.24 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.24 |
| DTX2 | deltex 2, E3 ubiquitin ligase | 0.24 |
| TMEM200A | transmembrane protein 200A | 0.24 |
| RAB27B | RAB27B, member RAS oncogene family | 0.24 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PIP | prolactin-induced protein | -1.49 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.87 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.8 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.68 |
| SMC1B | structural maintenance of chromosomes 1B | -0.64 |
| NAAA | N-acylethanolamine acid amidase | -0.63 |
| WHAMM | WAS protein homolog associated with actin, golgi membranes and microtubules | -0.59 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.56 |
| KPTN | kaptin (actin binding protein) | -0.56 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.54 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.53 |
| COL13A1 | collagen, type XIII, alpha 1 | -0.52 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | -0.47 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.47 |
| MADD | MAP-kinase activating death domain | -0.46 |
| C9ORF40 | chromosome 9 open reading frame 40 | -0.46 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.46 |
| ZBTB46 | zinc finger and BTB domain containing 46 | -0.45 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | -0.45 |
| FAM241B | family with sequence similarity 241 member B | -0.44 |
| STMN2 | stathmin 2 | -0.44 |
| SRRD | SRR1 domain containing | -0.43 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 | -0.42 |
| CCND3 | cyclin D3 | -0.42 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -0.42 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.42 |
| PHPT1 | phosphohistidine phosphatase 1 | -0.41 |
| DERPC | DERPC proline and glycine rich nuclear protein | -0.4 |
| TOR4A | torsin family 4, member A | -0.4 |
| FURIN | furin (paired basic amino acid cleaving enzyme) | -0.39 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.39 |
| ABHD18 | abhydrolase domain containing 18 | -0.37 |
| KLHL29 | kelch-like family member 29 | -0.37 |
| PLPP6 | phospholipid phosphatase 6 | -0.37 |
| SLC26A11 | solute carrier family 26 (anion exchanger), member 11 | -0.37 |
| TEN1 | TEN1 CST complex subunit | -0.36 |
| HIST1H1T | histone cluster 1, H1t | -0.35 |
| MBOAT1 | membrane bound O-acyltransferase domain containing 1 | -0.35 |
| SETD9 | SET domain containing 9 | -0.34 |
| LYRM1 | LYR motif containing 1 | -0.34 |
| CINP | cyclin-dependent kinase 2 interacting protein | -0.34 |
| SELENOW | selenoprotein W | -0.34 |
| COMMD6 | COMM domain containing 6 | -0.34 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.34 |
| ARHGAP28 | Rho GTPase activating protein 28 | -0.34 |
| ZNF2 | zinc finger protein 2 | -0.33 |
| LMX1B | LIM homeobox transcription factor 1, beta | -0.33 |
| CROCC2 | ciliary rootlet coiled-coil, rootletin family member 2 | -0.33 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) | -0.32 |
| MCOLN1 | mucolipin 1 | -0.32 |
| PCTP | phosphatidylcholine transfer protein | -0.32 |
| PDCD7 | programmed cell death 7 | -0.32 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.32 |
| ATG4D | autophagy related 4D, cysteine peptidase | -0.31 |
| B2M | beta-2-microglobulin | -0.31 |
| ENO1 | enolase 1, (alpha) | -0.31 |
| HLA-E | major histocompatibility complex, class I, E | -0.31 |
| HINT2 | histidine triad nucleotide binding protein 2 | -0.3 |
| BPTF | bromodomain PHD finger transcription factor | -0.3 |
| NOL12 | nucleolar protein 12 | -0.29 |
| TMEM64 | transmembrane protein 64 | -0.29 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.29 |
| KDM8 | lysine (K)-specific demethylase 8 | -0.29 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -0.28 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.28 |
| PSAP | prosaposin | -0.28 |
| NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2 | -0.28 |
| ZNF274 | zinc finger protein 274 | -0.28 |
| AMACR | alpha-methylacyl-CoA racemase | -0.28 |
| FAM110C | family with sequence similarity 110, member C | -0.28 |
| XTBD1 | XRN2 binding domain containing 1 | -0.28 |
| DESI2 | desumoylating isopeptidase 2 | -0.27 |
| DST | dystonin | -0.27 |
| ANGPTL4 | angiopoietin-like 4 | -0.27 |
| ASB7 | ankyrin repeat and SOCS box containing 7 | -0.26 |
| ZDHHC23 | zinc finger, DHHC-type containing 23 | -0.26 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.26 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.26 |
| TRIM68 | tripartite motif containing 68 | -0.26 |
| PUSL1 | pseudouridylate synthase-like 1 | -0.26 |
| KCTD17 | potassium channel tetramerization domain containing 17 | -0.25 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.25 |
| ANO8 | anoctamin 8 | -0.25 |
| CSTF2 | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | -0.25 |
| CASZ1 | castor zinc finger 1 | -0.25 |
| FAM193B | family with sequence similarity 193, member B | -0.25 |
| ZNF142 | zinc finger protein 142 | -0.25 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 | -0.25 |
| ZWINT | ZW10 interacting kinetochore protein | -0.24 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | -0.24 |
| RBFA | ribosome binding factor A (putative) | -0.24 |
| CTHRC1 | collagen triple helix repeat containing 1 | -0.24 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.24 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.24 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | -0.23 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.23 |
| CORO1A | coronin, actin binding protein, 1A | -0.23 |
| DOCK10 | dedicator of cytokinesis 10 | -0.23 |
| EPN3 | epsin 3 | -0.23 |
