| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temsirolimus perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Temsirolimus_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLE4 | transducin-like enhancer of split 4 | 0.0660566 |
| LPIN1 | lipin 1 | 0.0591927 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.058945 |
| VCL | vinculin | 0.0516703 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0350545 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0341317 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0327114 |
| HSPA1B | heat shock 70kDa protein 1B | 0.032467 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0319009 |
| MED13 | mediator complex subunit 13 | 0.0305772 |
| HOMER1 | homer scaffolding protein 1 | 0.0294204 |
| INTS6 | integrator complex subunit 6 | 0.0285671 |
| RIGI | RNA sensor RIG-I | 0.0278677 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0273433 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0267056 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0261692 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0261432 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0254422 |
| RNF213 | ring finger protein 213 | 0.0254222 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0253094 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0250303 |
| PARD3 | par-3 family cell polarity regulator | 0.025019 |
| ACTN1 | actinin, alpha 1 | 0.0245937 |
| VMP1 | vacuole membrane protein 1 | 0.0244689 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0240684 |
| CTBP2 | C-terminal binding protein 2 | 0.0237935 |
| SEPTIN9 | septin 9 | 0.0237816 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0236501 |
| RBM33 | RNA binding motif protein 33 | 0.0233824 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0229311 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0228389 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0228137 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.022466 |
| CHD6 | chromodomain helicase DNA binding protein 6 | 0.0220163 |
| EGFR | epidermal growth factor receptor | 0.0219133 |
| GOLGB1 | golgin B1 | 0.0219081 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0218698 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0216511 |
| FAM13B | family with sequence similarity 13, member B | 0.0216143 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0213723 |
| DUSP10 | dual specificity phosphatase 10 | 0.0209692 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.020956 |
| GLCCI1 | glucocorticoid induced 1 | 0.0208302 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0207998 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.020732 |
| AUTS2 | autism susceptibility candidate 2 | 0.0203989 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.02035 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0200957 |
| USP34 | ubiquitin specific peptidase 34 | 0.0199196 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0198834 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0198687 |
| MYO1E | myosin IE | 0.0198461 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0198453 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0196634 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0195485 |
| ZNF644 | zinc finger protein 644 | 0.0194907 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0194423 |
| SMAD3 | SMAD family member 3 | 0.0192088 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0191573 |
| GLG1 | golgi glycoprotein 1 | 0.0191004 |
| EP300 | E1A binding protein p300 | 0.0190577 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | 0.0190094 |
| PALLD | palladin, cytoskeletal associated protein | 0.0185311 |
| MED13L | mediator complex subunit 13-like | 0.0185228 |
| RASAL2 | RAS protein activator like 2 | 0.0185197 |
| KIF21A | kinesin family member 21A | 0.0184822 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.018272 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0181672 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) | 0.0181296 |
| ATXN1 | ataxin 1 | 0.0180979 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.017917 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0178904 |
| PRKCA | protein kinase C, alpha | 0.0177161 |
| RBM25 | RNA binding motif protein 25 | 0.0176953 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0176479 |
| STXBP4 | syntaxin binding protein 4 | 0.0175534 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.017527 |
| RBM26 | RNA binding motif protein 26 | 0.0174824 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0173831 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.01737 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0173616 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0173601 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0173089 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0172433 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0170421 |
| NPAS2 | neuronal PAS domain protein 2 | 0.016988 |
| CEP350 | centrosomal protein 350kDa | 0.0169057 |
| EP400 | E1A binding protein p400 | 0.0168911 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.016858 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0165902 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0165267 |
| FLNA | filamin A, alpha | 0.0165186 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0164768 |
| OXSR1 | oxidative stress responsive 1 | 0.0162838 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0162418 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0162043 |
| PI4KB | phosphatidylinositol 4-kinase, catalytic, beta | 0.0161726 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0160995 |
| USP36 | ubiquitin specific peptidase 36 | 0.0160891 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0160789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.255055 |
| IGF2 | insulin-like growth factor 2 | -0.177343 |
| VIM | vimentin | -0.118183 |
| LSAMP | limbic system-associated membrane protein | -0.116345 |
| PTMA | prothymosin, alpha | -0.11115 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.105387 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0963604 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0958248 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0932965 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0837811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0755645 |
| FAM13A | family with sequence similarity 13, member A | -0.0738104 |
| RPS6 | ribosomal protein S6 | -0.0677677 |
| NDRG1 | N-myc downstream regulated 1 | -0.0586636 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0578566 |
| RPS24 | ribosomal protein S24 | -0.057731 |
| MEIS2 | Meis homeobox 2 | -0.0547071 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.054247 |
| RPL35A | ribosomal protein L35a | -0.0517349 |
| MAP1B | microtubule-associated protein 1B | -0.0516193 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0508695 |
| MEF2A | myocyte enhancer factor 2A | -0.0493585 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0486516 |
| FMN1 | formin 1 | -0.0484372 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0475691 |
| DTNA | dystrobrevin, alpha | -0.0474769 |
| SYT1 | synaptotagmin I | -0.044437 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0442599 |
| B2M | beta-2-microglobulin | -0.0439167 |
| RPL23 | ribosomal protein L23 | -0.0438629 |
| COL1A1 | collagen, type I, alpha 1 | -0.043408 |
| HELZ | helicase with zinc finger | -0.0431198 |
| RPS8 | ribosomal protein S8 | -0.0406692 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0403665 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0400658 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0398034 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0397997 |
| RPL19 | ribosomal protein L19 | -0.0391794 |
| RPLP1 | ribosomal protein, large, P1 | -0.0389057 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0383857 |
| CADM2 | cell adhesion molecule 2 | -0.0371748 |
| RPS3 | ribosomal protein S3 | -0.0371019 |
| CRH | corticotropin releasing hormone | -0.0369962 |
| ENO1 | enolase 1, (alpha) | -0.0368094 |
| RPL12 | ribosomal protein L12 | -0.0355433 |
| RPS12 | ribosomal protein S12 | -0.0349787 |
| FAM162A | family with sequence similarity 162, member A | -0.0349729 |
| RPLP0 | ribosomal protein, large, P0 | -0.0342733 |
| IER3 | immediate early response 3 | -0.0341342 |
| RPL31 | ribosomal protein L31 | -0.0341237 |
| RPS19 | ribosomal protein S19 | -0.0338673 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0338545 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0337352 |
| PGK1 | phosphoglycerate kinase 1 | -0.0335944 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0335232 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0334863 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0325365 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0322474 |
| WDR45B | WD repeat domain 45B | -0.0317146 |
| SETD5 | SET domain containing 5 | -0.031639 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0316221 |
| RPL34 | ribosomal protein L34 | -0.0314529 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0314107 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0312924 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.031071 |
| TRIB2 | tribbles pseudokinase 2 | -0.031019 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0308656 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0307947 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0306218 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0302832 |
| RPS2 | ribosomal protein S2 | -0.0298117 |
| GNAS | GNAS complex locus | -0.0297355 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.029654 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0293301 |
| FTL | ferritin, light polypeptide | -0.0289969 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0287952 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0283319 |
| RPL36 | ribosomal protein L36 | -0.028155 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0278475 |
| RPS5 | ribosomal protein S5 | -0.0276514 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0275929 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0270327 |
| FNBP1 | formin binding protein 1 | -0.0269893 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0269335 |
| RPL32 | ribosomal protein L32 | -0.0267969 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0265524 |
| CALD1 | caldesmon 1 | -0.0262498 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.026048 |
| SET | SET nuclear proto-oncogene | -0.0259898 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0255938 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0253274 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0253216 |
| NUP58 | nucleoporin 58 | -0.0246886 |
| RPS27A | ribosomal protein S27a | -0.0246799 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0242434 |
| RPL26 | ribosomal protein L26 | -0.0241313 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0241005 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0239561 |
| ANGPT1 | angiopoietin 1 | -0.0236136 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0234747 |
