| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temsirolimus perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temsirolimus_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.184391 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.182428 |
| INTS6 | integrator complex subunit 6 | 0.12824 |
| RNF213 | ring finger protein 213 | 0.113623 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.112977 |
| SMAD3 | SMAD family member 3 | 0.0978375 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0764329 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.07534 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0691959 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0681371 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0636748 |
| EXT1 | exostosin glycosyltransferase 1 | 0.058984 |
| PLSCR2 | phospholipid scramblase 2 | 0.0525688 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0506133 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0505723 |
| RIGI | RNA sensor RIG-I | 0.0492666 |
| SP100 | SP100 nuclear antigen | 0.0486067 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0471245 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0465012 |
| ANXA2 | annexin A2 | 0.0455219 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0451217 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.04391 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0436257 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0434486 |
| EFNB2 | ephrin-B2 | 0.0415221 |
| KYNU | kynureninase | 0.0398746 |
| VMP1 | vacuole membrane protein 1 | 0.0396747 |
| MX1 | MX dynamin-like GTPase 1 | 0.039389 |
| DST | dystonin | 0.0386556 |
| FNIP2 | folliculin interacting protein 2 | 0.0375479 |
| NABP1 | nucleic acid binding protein 1 | 0.0375045 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0371442 |
| DIAPH1 | diaphanous-related formin 1 | 0.0370114 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0363557 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.035688 |
| VCL | vinculin | 0.0344739 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0330257 |
| TOX3 | TOX high mobility group box family member 3 | 0.0325542 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0316591 |
| HKDC1 | hexokinase domain containing 1 | 0.0309551 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0296944 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0292141 |
| TJP1 | tight junction protein 1 | 0.0289439 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0276877 |
| UBAP2 | ubiquitin associated protein 2 | 0.0272561 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0270019 |
| RBM47 | RNA binding motif protein 47 | 0.026598 |
| PDZD8 | PDZ domain containing 8 | 0.0263972 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0261854 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0253216 |
| AREG | amphiregulin | 0.0249315 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0247518 |
| RAD51B | RAD51 paralog B | 0.0240527 |
| KIAA1217 | KIAA1217 | 0.0238081 |
| LAMA4 | laminin, alpha 4 | 0.0237693 |
| SQSTM1 | sequestosome 1 | 0.0235204 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0233311 |
| STK24 | serine/threonine kinase 24 | 0.022906 |
| PLSCR1 | phospholipid scramblase 1 | 0.0227172 |
| HOMER1 | homer scaffolding protein 1 | 0.0226895 |
| POU2F2 | POU class 2 homeobox 2 | 0.0225876 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.022436 |
| POF1B | premature ovarian failure, 1B | 0.0224088 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0222723 |
| ARHGAP27 | Rho GTPase activating protein 27 | 0.021555 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0213396 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0211475 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0209971 |
| CTBP2 | C-terminal binding protein 2 | 0.020976 |
| MYO5B | myosin VB | 0.0208431 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0208353 |
| TPP2 | tripeptidyl peptidase II | 0.0205932 |
| MCU | mitochondrial calcium uniporter | 0.0205745 |
| PRSS22 | protease, serine, 22 | 0.0204991 |
| GK | glycerol kinase | 0.0204681 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0204507 |
| ERBIN | erbb2 interacting protein | 0.0202771 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0201671 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0200902 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0200488 |
| DUSP10 | dual specificity phosphatase 10 | 0.0199254 |
| PRKCE | protein kinase C, epsilon | 0.019901 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0197886 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0196635 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0195417 |
| PSEN1 | presenilin 1 | 0.0194031 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0191809 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0191725 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0191688 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0187322 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0184962 |
| TRIM25 | tripartite motif containing 25 | 0.0181387 |
| WWOX | WW domain containing oxidoreductase | 0.0179925 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.017838 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0176499 |
| FBXO39 | F-box protein 39 | 0.0175515 |
| SETX | senataxin | 0.0175391 |
| SLC25A25 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 | 0.0173926 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0172584 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0172085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.186623 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.167202 |
| B2M | beta-2-microglobulin | -0.150797 |
| PTMA | prothymosin, alpha | -0.132975 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112814 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.110961 |
| HLA-B | major histocompatibility complex, class I, B | -0.0942263 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0861131 |
| LCN2 | lipocalin 2 | -0.0837451 |
| NDRG1 | N-myc downstream regulated 1 | -0.0834541 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0803877 |
| TXNIP | thioredoxin interacting protein | -0.0724967 |
| CANX | calnexin | -0.0675667 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0674608 |
| RNF149 | ring finger protein 149 | -0.0631926 |
| H1-0 | H1.0 linker histone | -0.0620784 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0606213 |
| FTL | ferritin, light polypeptide | -0.0603112 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0596707 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0587606 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0586452 |
| RPS6 | ribosomal protein S6 | -0.0578322 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.054581 |
| PGK1 | phosphoglycerate kinase 1 | -0.0541164 |
| RPL35A | ribosomal protein L35a | -0.0526007 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0513561 |
| ENO1 | enolase 1, (alpha) | -0.051129 |
| AHI1 | Abelson helper integration site 1 | -0.0505237 |
| HLA-E | major histocompatibility complex, class I, E | -0.0489475 |
| LYZ | lysozyme | -0.0482396 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.046389 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0460348 |
| GOLGA4 | golgin A4 | -0.0454042 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0450447 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0444723 |
| UBC | ubiquitin C | -0.0443821 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0442926 |
| RPL12 | ribosomal protein L12 | -0.0441894 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0431518 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0428154 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0426309 |
| EPCAM | epithelial cell adhesion molecule | -0.0424598 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0417537 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0412014 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0410106 |
| WDR45B | WD repeat domain 45B | -0.0409298 |
| LDHA | lactate dehydrogenase A | -0.0407818 |
| DSTN | destrin (actin depolymerizing factor) | -0.0407082 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0400505 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0390781 |
| CALR | calreticulin | -0.0387538 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0384666 |
| RPL34 | ribosomal protein L34 | -0.0383575 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0383068 |
| MORF4L2 | mortality factor 4 like 2 | -0.0373202 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0373197 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0373067 |
| TMSB10 | thymosin beta 10 | -0.0369997 |
| RBM39 | RNA binding motif protein 39 | -0.0369435 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0368972 |
| RPL23 | ribosomal protein L23 | -0.0367221 |
| RPL19 | ribosomal protein L19 | -0.0366892 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0364101 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0362232 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0356424 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0351633 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0351429 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0343346 |
| RPS8 | ribosomal protein S8 | -0.0341977 |
| PTEN | phosphatase and tensin homolog | -0.0341624 |
| MT2A | metallothionein 2A | -0.0341357 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0335349 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.033034 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0327926 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0326203 |
| EZR | ezrin | -0.0325573 |
| RPL26 | ribosomal protein L26 | -0.0325036 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0317352 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0315416 |
| HLA-A | major histocompatibility complex, class I, A | -0.031394 |
| PHF3 | PHD finger protein 3 | -0.0313923 |
| CEP350 | centrosomal protein 350kDa | -0.0313625 |
| RPS24 | ribosomal protein S24 | -0.0311867 |
| HDLBP | high density lipoprotein binding protein | -0.031115 |
| AHNAK | AHNAK nucleoprotein | -0.0310098 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0309816 |
| H3-3B | H3.3 histone B | -0.0308141 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.030804 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0307497 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0305298 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0305254 |
| CMIP | c-Maf inducing protein | -0.030217 |
| TPM4 | tropomyosin 4 | -0.0301676 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0301049 |
| GNAS | GNAS complex locus | -0.0299289 |
| GOLGA2 | golgin A2 | -0.0293256 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0291678 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0290717 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0290168 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0288821 |
