| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temsirolimus perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temsirolimus_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0990532 |
| RPL3 | ribosomal protein L3 | 0.0699376 |
| VEGFA | vascular endothelial growth factor A | 0.0601525 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0466509 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0430871 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0399449 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0392546 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0376359 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0371039 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0323205 |
| KRT8 | keratin 8, type II | 0.0295605 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0293611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0275306 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0267601 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0254751 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0243386 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0228345 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0216453 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0209316 |
| FAT1 | FAT atypical cadherin 1 | 0.0207728 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0205089 |
| DSPP | dentin sialophosphoprotein | 0.020483 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0203999 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.020133 |
| TMF1 | TATA element modulatory factor 1 | 0.0201193 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0195701 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0192837 |
| PLEC | plectin | 0.0191624 |
| COPA | coatomer protein complex, subunit alpha | 0.0189166 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0188081 |
| HYOU1 | hypoxia up-regulated 1 | 0.0186084 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0185412 |
| FAM13A | family with sequence similarity 13, member A | 0.0184468 |
| DNM2 | dynamin 2 | 0.0183992 |
| CALR | calreticulin | 0.0180502 |
| RNF145 | ring finger protein 145 | 0.0180184 |
| ABHD2 | abhydrolase domain containing 2 | 0.0179562 |
| RPL4 | ribosomal protein L4 | 0.0176877 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0171075 |
| POTEF | POTE ankyrin domain family, member F | 0.0165393 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0156555 |
| ANXA1 | annexin A1 | 0.0152989 |
| GOLGA4 | golgin A4 | 0.0150221 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0148346 |
| PCBP2 | poly(rC) binding protein 2 | 0.0145971 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0142142 |
| ZNF91 | zinc finger protein 91 | 0.0139467 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0138997 |
| PTEN | phosphatase and tensin homolog | 0.0136045 |
| TPM3 | tropomyosin 3 | 0.0136023 |
| NDRG1 | N-myc downstream regulated 1 | 0.0135981 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0134936 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0133072 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0131994 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0131328 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0130726 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0130089 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.012963 |
| NCOR2 | nuclear receptor corepressor 2 | 0.012955 |
| MED13L | mediator complex subunit 13-like | 0.0128964 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0127654 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0126103 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.012414 |
| ERBIN | erbb2 interacting protein | 0.0120403 |
| CLDN7 | claudin 7 | 0.0120355 |
| RPL21 | ribosomal protein L21 | 0.0117943 |
| ZNF292 | zinc finger protein 292 | 0.0117171 |
| CASZ1 | castor zinc finger 1 | 0.0116297 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0114978 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0114875 |
| SLK | STE20-like kinase | 0.0113295 |
| ZFP36 | ZFP36 ring finger protein | 0.0113235 |
| RPS18 | ribosomal protein S18 | 0.011307 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0111435 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0111429 |
| DIAPH1 | diaphanous-related formin 1 | 0.0110103 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0109744 |
| NUP58 | nucleoporin 58 | 0.0109105 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0108916 |
| PKM | pyruvate kinase, muscle | 0.0106376 |
| CALB1 | calbindin 1, 28kDa | 0.0105925 |
| PER2 | period circadian clock 2 | 0.0105846 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0104979 |
| RPS26 | ribosomal protein S26 | 0.0104194 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0104158 |
| MLF1 | myeloid leukemia factor 1 | 0.0104094 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.010392 |
| PRPF8 | pre-mRNA processing factor 8 | 0.010274 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0102487 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0102094 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.010056 |
| LMO7 | LIM domain 7 | 0.00993732 |
| GSE1 | Gse1 coiled-coil protein | 0.00992799 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00990814 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00986441 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0097907 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00977293 |
| GATA6 | GATA binding protein 6 | 0.00974417 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00974023 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.00973772 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.256148 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.203854 |
| NPSR1 | neuropeptide S receptor 1 | -0.183736 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.182128 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115551 |
| TMSB10 | thymosin beta 10 | -0.112223 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.095663 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0956105 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0936006 |
| ANXA2 | annexin A2 | -0.0866572 |
| VCL | vinculin | -0.0831647 |
| ACTG1 | actin gamma 1 | -0.0695376 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0666185 |
| EPCAM | epithelial cell adhesion molecule | -0.0628724 |
| RPS24 | ribosomal protein S24 | -0.0587286 |
| GPHN | gephyrin | -0.0583767 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0576195 |
| S100A6 | S100 calcium binding protein A6 | -0.0561503 |
| ONECUT3 | one cut homeobox 3 | -0.0559906 |
| RPS6 | ribosomal protein S6 | -0.055205 |
| IER3 | immediate early response 3 | -0.0529925 |
| RPLP1 | ribosomal protein, large, P1 | -0.0521967 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0511373 |
| RPL35A | ribosomal protein L35a | -0.0510474 |
| RPL34 | ribosomal protein L34 | -0.049069 |
| RPL9 | ribosomal protein L9 | -0.0479586 |
| TPM4 | tropomyosin 4 | -0.0478739 |
| FLNB | filamin B, beta | -0.0471948 |
| CADPS | Ca++-dependent secretion activator | -0.0456335 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0452802 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0445649 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0440325 |
| RPL26 | ribosomal protein L26 | -0.0440201 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0432183 |
| RPL12 | ribosomal protein L12 | -0.0427985 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0425885 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0424215 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0422977 |
| CCND1 | cyclin D1 | -0.0422269 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0409397 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0401419 |
| PGK1 | phosphoglycerate kinase 1 | -0.0399621 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0394425 |
| RPS8 | ribosomal protein S8 | -0.0392115 |
| NFIA | nuclear factor I/A | -0.0384539 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0383904 |
| RPS27A | ribosomal protein S27a | -0.0381497 |
| CD44 | CD44 molecule (Indian blood group) | -0.0380726 |
| AHNAK | AHNAK nucleoprotein | -0.0379921 |
| EXT1 | exostosin glycosyltransferase 1 | -0.037911 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0374185 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0370553 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0362606 |
| RPS3 | ribosomal protein S3 | -0.036144 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0360051 |
| LDHA | lactate dehydrogenase A | -0.0359156 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0352887 |
| RPL11 | ribosomal protein L11 | -0.0352491 |
| RPLP0 | ribosomal protein, large, P0 | -0.0349974 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0348339 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0348006 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0347353 |
| FHIT | fragile histidine triad | -0.0342874 |
| RPL31 | ribosomal protein L31 | -0.0342774 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.032966 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0326058 |
| RPL37A | ribosomal protein L37a | -0.0321871 |
| RAB10 | RAB10, member RAS oncogene family | -0.0321082 |
| POF1B | premature ovarian failure, 1B | -0.0317243 |
| FERMT1 | fermitin family member 1 | -0.0317038 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0315463 |
| PRELID2 | PRELI domain containing 2 | -0.0310744 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0309467 |
| SMYD3 | SET and MYND domain containing 3 | -0.030932 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0309173 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0307475 |
| RPS25 | ribosomal protein S25 | -0.0306994 |
| S100A10 | S100 calcium binding protein A10 | -0.030557 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0303255 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0298813 |
| RPL7A | ribosomal protein L7a | -0.0296743 |
| B2M | beta-2-microglobulin | -0.0295886 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0294014 |
| ITGA6 | integrin, alpha 6 | -0.0292842 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0289797 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0287707 |
| PALLD | palladin, cytoskeletal associated protein | -0.028739 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0285646 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0284116 |
| RPS29 | ribosomal protein S29 | -0.0282784 |
| PKP2 | plakophilin 2 | -0.0282781 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0279821 |
| HDAC2 | histone deacetylase 2 | -0.0279691 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0279498 |
| RPL36 | ribosomal protein L36 | -0.0278474 |
| MYO1E | myosin IE | -0.0277148 |
| FRMD5 | FERM domain containing 5 | -0.0275232 |
| RPS19 | ribosomal protein S19 | -0.0274217 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0273424 |
| RACK1 | receptor for activated C kinase 1 | -0.0271771 |
