| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temsirolimus perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Temsirolimus_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.213601 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.125809 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.110821 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.082449 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0753768 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.071042 |
| NTN4 | netrin 4 | 0.0671325 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.062868 |
| S100A6 | S100 calcium binding protein A6 | 0.0627973 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0589242 |
| CD44 | CD44 molecule (Indian blood group) | 0.0584584 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0580282 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0566293 |
| GLCCI1 | glucocorticoid induced 1 | 0.0564166 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0558209 |
| VIM | vimentin | 0.0556944 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0548125 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0521224 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0519776 |
| NRG1 | neuregulin 1 | 0.0512946 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0512799 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0501984 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0498608 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0497359 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.047605 |
| TGM2 | transglutaminase 2 | 0.0473409 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0467515 |
| NRP1 | neuropilin 1 | 0.0464748 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0459413 |
| DOCK5 | dedicator of cytokinesis 5 | 0.045298 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0447132 |
| SMAD3 | SMAD family member 3 | 0.0437688 |
| PLIN2 | perilipin 2 | 0.0421105 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0419342 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0417856 |
| KYNU | kynureninase | 0.0416209 |
| PCNX1 | pecanex 1 | 0.0415632 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.041404 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0407306 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0405607 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0399404 |
| CALU | calumenin | 0.0394304 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0383989 |
| RHCG | Rh family, C glycoprotein | 0.0382083 |
| NUMB | numb homolog (Drosophila) | 0.0373826 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0364874 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0360701 |
| NAV2 | neuron navigator 2 | 0.0359392 |
| AHI1 | Abelson helper integration site 1 | 0.0353969 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0348969 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0347382 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0345266 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0338113 |
| IL6ST | interleukin 6 signal transducer | 0.033605 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0329432 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0327718 |
| STC1 | stanniocalcin 1 | 0.032285 |
| RPS21 | ribosomal protein S21 | 0.032245 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0321288 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0309362 |
| EHBP1 | EH domain binding protein 1 | 0.0308735 |
| FNIP2 | folliculin interacting protein 2 | 0.0308076 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0305555 |
| ENO1 | enolase 1, (alpha) | 0.0304844 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0304734 |
| ADM | adrenomedullin | 0.0304283 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0302561 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0298657 |
| VRK2 | vaccinia related kinase 2 | 0.0295775 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0294241 |
| ACTN4 | actinin, alpha 4 | 0.0292135 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.029203 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0290994 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0290639 |
| RARB | retinoic acid receptor, beta | 0.0289605 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0288925 |
| THBD | thrombomodulin | 0.0286614 |
| BPTF | bromodomain PHD finger transcription factor | 0.028624 |
| SP100 | SP100 nuclear antigen | 0.0286024 |
| RNF24 | ring finger protein 24 | 0.0285963 |
| ADD3 | adducin 3 (gamma) | 0.0285302 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0283165 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0282365 |
| SUSD6 | sushi domain containing 6 | 0.0282255 |
| LOX | lysyl oxidase | 0.0281372 |
| TMEM131 | transmembrane protein 131 | 0.0279736 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.027809 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0277152 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0276077 |
| SRGN | serglycin | 0.0275605 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0274813 |
| HIP1 | huntingtin interacting protein 1 | 0.0273967 |
| OXSR1 | oxidative stress responsive 1 | 0.0272817 |
| LAMA4 | laminin, alpha 4 | 0.0269852 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0268524 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0267616 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0265665 |
| TMSB10 | thymosin beta 10 | 0.0264888 |
| UBC | ubiquitin C | 0.0262873 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0261558 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | -0.167465 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.146705 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.137135 |
| NDRG1 | N-myc downstream regulated 1 | -0.0786088 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0748623 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0733492 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0718102 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0704528 |
| CDH13 | cadherin 13 | -0.0684055 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0616498 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0614781 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0575898 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.057442 |
| MECOM | MDS1 and EVI1 complex locus | -0.0545694 |
| GPC6 | glypican 6 | -0.0519509 |
| RAD51B | RAD51 paralog B | -0.0498256 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0493939 |
| RPS12 | ribosomal protein S12 | -0.045986 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0459775 |
| ZNF804A | zinc finger protein 804A | -0.0457049 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0455987 |
| FN1 | fibronectin 1 | -0.0455054 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0454925 |
| USP34 | ubiquitin specific peptidase 34 | -0.0448648 |
| PRELID2 | PRELI domain containing 2 | -0.0445776 |
| PCBP2 | poly(rC) binding protein 2 | -0.0432314 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0424215 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0422678 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0416299 |
| CFAP20DC | CFAP20 domain containing | -0.0415627 |
| TBC1D22A | TBC1 domain family, member 22A | -0.041555 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0413086 |
| HDAC9 | histone deacetylase 9 | -0.0400343 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0395263 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0395057 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0388923 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376446 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0374673 |
| RPL13A | ribosomal protein L13a | -0.0363697 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0362177 |
| MTSS1 | metastasis suppressor 1 | -0.035126 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0349726 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0347061 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0346414 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0345019 |
| FAM107B | family with sequence similarity 107, member B | -0.0341015 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0338733 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0334979 |
| RAI14 | retinoic acid induced 14 | -0.0334805 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0324028 |
| RPS19 | ribosomal protein S19 | -0.0312078 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0311983 |
| ATXN1 | ataxin 1 | -0.0311872 |
| DST | dystonin | -0.0311798 |
| OGA | O-GlcNAcase | -0.0311054 |
| TNNC1 | troponin C type 1 (slow) | -0.0310337 |
| MCL1 | myeloid cell leukemia 1 | -0.0309253 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0304756 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0303164 |
| CDK14 | cyclin-dependent kinase 14 | -0.0302826 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0299538 |
| HDAC4 | histone deacetylase 4 | -0.0295134 |
| NAV3 | neuron navigator 3 | -0.0292049 |
| YBX1 | Y box binding protein 1 | -0.0288995 |
| CMIP | c-Maf inducing protein | -0.0285384 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0283327 |
| FAM13A | family with sequence similarity 13, member A | -0.0282785 |
| RUNX1 | runt-related transcription factor 1 | -0.0281343 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0280234 |
| JMJD1C | jumonji domain containing 1C | -0.0279794 |
| RPL12 | ribosomal protein L12 | -0.0276135 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0274486 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0271791 |
| HMGA1 | high mobility group AT-hook 1 | -0.0271577 |
| SNX14 | sorting nexin 14 | -0.0271318 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0270857 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0269997 |
| CCDC88A | coiled-coil domain containing 88A | -0.0268215 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0266601 |
| DIAPH2 | diaphanous-related formin 2 | -0.0265398 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0264079 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0262146 |
| CDC73 | cell division cycle 73 | -0.0260885 |
| EGR1 | early growth response 1 | -0.0260463 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0260426 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0257959 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0256869 |
| NAV1 | neuron navigator 1 | -0.0250751 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0250215 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0246428 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0245923 |
| KLF12 | Kruppel-like factor 12 | -0.0245593 |
| PRKCA | protein kinase C, alpha | -0.0244192 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0241803 |
| PTMA | prothymosin, alpha | -0.0240658 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0239054 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0234876 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0234651 |
| EFL1 | elongation factor like GTPase 1 | -0.0234502 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0234297 |
