| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temsirolimus perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temsirolimus_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0699746 |
| NAV2 | neuron navigator 2 | 0.0698434 |
| SPAG9 | sperm associated antigen 9 | 0.060308 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0489587 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0405909 |
| FN1 | fibronectin 1 | 0.0394081 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0380759 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0348318 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0319047 |
| HELZ | helicase with zinc finger | 0.0293455 |
| RPL3 | ribosomal protein L3 | 0.0255339 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0229478 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0226636 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0215074 |
| DUSP10 | dual specificity phosphatase 10 | 0.0210831 |
| OGA | O-GlcNAcase | 0.0206408 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0202158 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0194404 |
| GOLGA4 | golgin A4 | 0.0193353 |
| FLNA | filamin A, alpha | 0.019224 |
| NEK7 | NIMA-related kinase 7 | 0.01867 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0185165 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0183728 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0183076 |
| CEP250 | centrosomal protein 250kDa | 0.0180889 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0180597 |
| KYNU | kynureninase | 0.0178097 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0176999 |
| WTAP | Wilms tumor 1 associated protein | 0.0176443 |
| TXNRD1 | thioredoxin reductase 1 | 0.0175889 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.017579 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0174146 |
| HBS1L | HBS1-like translational GTPase | 0.0174142 |
| HDAC9 | histone deacetylase 9 | 0.0170964 |
| NCKAP1 | NCK-associated protein 1 | 0.0170798 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0169456 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0169054 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.016802 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.016743 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0162819 |
| USP37 | ubiquitin specific peptidase 37 | 0.0162718 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0162633 |
| CLTC | clathrin, heavy chain (Hc) | 0.0162544 |
| NUP153 | nucleoporin 153kDa | 0.0158463 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0155946 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0150894 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0149535 |
| MYOF | myoferlin | 0.0148737 |
| AHR | aryl hydrocarbon receptor | 0.0146702 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0146564 |
| ANLN | anillin, actin binding protein | 0.0146146 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0146112 |
| FMNL2 | formin-like 2 | 0.014584 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0144093 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0143829 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0142986 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0142588 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0141377 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0139415 |
| CENPF | centromere protein F, 350/400kDa | 0.0139383 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0139191 |
| JMJD1C | jumonji domain containing 1C | 0.0138498 |
| CCDC93 | coiled-coil domain containing 93 | 0.0137247 |
| YBX1 | Y box binding protein 1 | 0.0136811 |
| SRP54 | signal recognition particle 54kDa | 0.0136252 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0135549 |
| ARRDC3 | arrestin domain containing 3 | 0.0135236 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0134471 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0134184 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0132202 |
| ZNF451 | zinc finger protein 451 | 0.0132188 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0131531 |
| YEATS2 | YEATS domain containing 2 | 0.0131321 |
| TJP2 | tight junction protein 2 | 0.0130728 |
| PLEC | plectin | 0.0130646 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0130437 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.012903 |
| ABI1 | abl-interactor 1 | 0.0127682 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0127515 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0126564 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0125761 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0125745 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0125587 |
| XPO1 | exportin 1 | 0.0125354 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0124467 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0124363 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0124262 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.012413 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0122884 |
| USP36 | ubiquitin specific peptidase 36 | 0.0122841 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0122233 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0122007 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0121561 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0121442 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.012072 |
| UVRAG | UV radiation resistance associated | 0.0120403 |
| CUL3 | cullin 3 | 0.0120221 |
| HLA-C | major histocompatibility complex, class I, C | 0.0120163 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0120096 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0120042 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.334287 |
| CD44 | CD44 molecule (Indian blood group) | -0.136071 |
| GLIS3 | GLIS family zinc finger 3 | -0.133982 |
| VCL | vinculin | -0.119438 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119078 |
| FRMD4A | FERM domain containing 4A | -0.114885 |
| HLA-B | major histocompatibility complex, class I, B | -0.113288 |
| FTL | ferritin, light polypeptide | -0.110588 |
| LDHA | lactate dehydrogenase A | -0.108706 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0984352 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0924262 |
| EGR1 | early growth response 1 | -0.0803835 |
| ENO1 | enolase 1, (alpha) | -0.080379 |
| IER3 | immediate early response 3 | -0.0801628 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0755922 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0755109 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0733001 |
| BICC1 | BicC family RNA binding protein 1 | -0.0666742 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0665171 |
| B2M | beta-2-microglobulin | -0.0659303 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0633106 |
| HLA-A | major histocompatibility complex, class I, A | -0.0627574 |
| TMSB10 | thymosin beta 10 | -0.062743 |
| NDRG1 | N-myc downstream regulated 1 | -0.0609966 |
| TPM4 | tropomyosin 4 | -0.0594223 |
| PGK1 | phosphoglycerate kinase 1 | -0.0592905 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0587068 |
| RPS3 | ribosomal protein S3 | -0.0569179 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0563576 |
| PLIN2 | perilipin 2 | -0.0556526 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0534422 |
| PTMA | prothymosin, alpha | -0.0532249 |
| HLA-E | major histocompatibility complex, class I, E | -0.0531995 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0526558 |
| GPC6 | glypican 6 | -0.0514766 |
| RPS12 | ribosomal protein S12 | -0.0489502 |
| RPL37A | ribosomal protein L37a | -0.0482623 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.047639 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0475788 |
| VCAN | versican | -0.0471378 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0454319 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0447694 |
| MT2A | metallothionein 2A | -0.0446681 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0436844 |
| CTSB | cathepsin B | -0.0434423 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0430299 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0430245 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0429363 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0420862 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0420109 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0417263 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0414061 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.040762 |
| NAV1 | neuron navigator 1 | -0.0397352 |
| CTSD | cathepsin D | -0.0392386 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0388716 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0388222 |
| DIAPH2 | diaphanous-related formin 2 | -0.0383871 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0377319 |
| RPL9 | ribosomal protein L9 | -0.0374842 |
| HMGA2 | high mobility group AT-hook 2 | -0.0369786 |
| PDE10A | phosphodiesterase 10A | -0.0369062 |
| RAI14 | retinoic acid induced 14 | -0.0364891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0364692 |
| C3 | complement component 3 | -0.0361394 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0354312 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0343029 |
| RPL36A | ribosomal protein L36a | -0.0339543 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.033626 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0334979 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0333231 |
| VMP1 | vacuole membrane protein 1 | -0.0331645 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0331201 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0330133 |
| RPS6 | ribosomal protein S6 | -0.0329686 |
| PALLD | palladin, cytoskeletal associated protein | -0.0323022 |
| OSMR | oncostatin M receptor | -0.032268 |
| STC1 | stanniocalcin 1 | -0.0315041 |
| ADM | adrenomedullin | -0.0313843 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0307895 |
| UBC | ubiquitin C | -0.0306847 |
| EGFR | epidermal growth factor receptor | -0.0299351 |
| RPS8 | ribosomal protein S8 | -0.0298365 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0297497 |
| KRT19 | keratin 19, type I | -0.0296021 |
| NABP1 | nucleic acid binding protein 1 | -0.0295342 |
| RPS27A | ribosomal protein S27a | -0.029522 |
| CDH13 | cadherin 13 | -0.0292626 |
| JUN | jun proto-oncogene | -0.0289914 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0289243 |
| IER2 | immediate early response 2 | -0.0283962 |
| COL1A1 | collagen, type I, alpha 1 | -0.0283189 |
| THBS1 | thrombospondin 1 | -0.0281996 |
| ANXA2 | annexin A2 | -0.0279614 |
| TPM1 | tropomyosin 1 (alpha) | -0.027815 |
| RTN4 | reticulon 4 | -0.0274338 |
| GNAS | GNAS complex locus | -0.0268189 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.026558 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0261636 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0256732 |
