| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temsirolimus perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Temsirolimus_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.090985 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0858924 |
| IL6 | interleukin 6 | 0.0756451 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0735579 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0699402 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0679526 |
| EGFR | epidermal growth factor receptor | 0.0640704 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0573007 |
| FNIP1 | folliculin interacting protein 1 | 0.0550196 |
| COL5A1 | collagen, type V, alpha 1 | 0.0516011 |
| VEGFA | vascular endothelial growth factor A | 0.0476614 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0432483 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.039997 |
| ZNF638 | zinc finger protein 638 | 0.0388555 |
| KYNU | kynureninase | 0.0379075 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0378668 |
| PLEC | plectin | 0.0374888 |
| PRELID2 | PRELI domain containing 2 | 0.0373892 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0369175 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0368504 |
| MSN | moesin | 0.0362877 |
| VEGFC | vascular endothelial growth factor C | 0.0359637 |
| NRXN3 | neurexin 3 | 0.0355727 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0346112 |
| RUNX1 | runt-related transcription factor 1 | 0.0336427 |
| CDH13 | cadherin 13 | 0.0332092 |
| TNS3 | tensin 3 | 0.0326338 |
| NBAS | neuroblastoma amplified sequence | 0.0323973 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0323665 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0314591 |
| FN1 | fibronectin 1 | 0.0313456 |
| STC2 | stanniocalcin 2 | 0.0306836 |
| NAV2 | neuron navigator 2 | 0.0305076 |
| POTEF | POTE ankyrin domain family, member F | 0.0304283 |
| DST | dystonin | 0.030291 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0292669 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0288452 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0281155 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0279559 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0275977 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0273124 |
| ATXN1 | ataxin 1 | 0.0271908 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0266565 |
| INSIG2 | insulin induced gene 2 | 0.0266519 |
| HYOU1 | hypoxia up-regulated 1 | 0.0255094 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0254664 |
| BRD2 | bromodomain containing 2 | 0.0254436 |
| CALR | calreticulin | 0.0253321 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0248295 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0247815 |
| FLNA | filamin A, alpha | 0.0247238 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0244467 |
| IGF2 | insulin-like growth factor 2 | 0.0243729 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0243266 |
| INTS6 | integrator complex subunit 6 | 0.0239144 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0238851 |
| RNF145 | ring finger protein 145 | 0.0238227 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0234952 |
| GSE1 | Gse1 coiled-coil protein | 0.0233387 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0233179 |
| TGFB1 | transforming growth factor, beta 1 | 0.0233101 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0232944 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.023194 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0230887 |
| FER | fer (fps/fes related) tyrosine kinase | 0.023024 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0229701 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.022618 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0225593 |
| SCFD1 | sec1 family domain containing 1 | 0.0223421 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0220886 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0219338 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0219305 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0218769 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0217175 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0213094 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0211938 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0210921 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0210678 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0210061 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0209088 |
| NOTCH2 | notch 2 | 0.0208313 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0207671 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0207604 |
| RND3 | Rho family GTPase 3 | 0.020759 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0207552 |
| HDAC9 | histone deacetylase 9 | 0.0206277 |
| FAM219A | family with sequence similarity 219, member A | 0.0205753 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0202954 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0202373 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0202173 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0201882 |
| YAP1 | Yes-associated protein 1 | 0.0200827 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0198495 |
| MAGT1 | magnesium transporter 1 | 0.0198082 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.0197991 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0196783 |
| FAM13B | family with sequence similarity 13, member B | 0.0195344 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.019478 |
| LSAMP | limbic system-associated membrane protein | 0.0193843 |
| MMP12 | matrix metallopeptidase 12 | 0.0192138 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.361822 |
| MT2A | metallothionein 2A | -0.224734 |
| TMSB10 | thymosin beta 10 | -0.157207 |
| VIM | vimentin | -0.148208 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.123783 |
| HLA-B | major histocompatibility complex, class I, B | -0.0930915 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0898419 |
| LOX | lysyl oxidase | -0.0808875 |
| PTMA | prothymosin, alpha | -0.0779882 |
| ANXA2 | annexin A2 | -0.0776275 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0767669 |
| COL1A2 | collagen, type I, alpha 2 | -0.0755848 |
| B2M | beta-2-microglobulin | -0.072498 |
| MT1X | metallothionein 1X | -0.0626584 |
| LOXL2 | lysyl oxidase-like 2 | -0.0608964 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0567481 |
| COL1A1 | collagen, type I, alpha 1 | -0.0561368 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0518843 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0514448 |
| NDRG1 | N-myc downstream regulated 1 | -0.0489493 |
| H3-3B | H3.3 histone B | -0.0483013 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0470048 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0457286 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0452777 |
| PRSS23 | protease, serine, 23 | -0.044298 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0420758 |
| STC1 | stanniocalcin 1 | -0.0414703 |
| FTL | ferritin, light polypeptide | -0.0406928 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.038289 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.037325 |
| ZNF292 | zinc finger protein 292 | -0.0371324 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0366381 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0365144 |
| S100A10 | S100 calcium binding protein A10 | -0.0360513 |
| SMAD3 | SMAD family member 3 | -0.0359355 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0357234 |
| OGA | O-GlcNAcase | -0.0356974 |
| AHNAK | AHNAK nucleoprotein | -0.0354797 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0343609 |
| HLA-C | major histocompatibility complex, class I, C | -0.034309 |
| RPL34 | ribosomal protein L34 | -0.0340596 |
| GNAS | GNAS complex locus | -0.0339366 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0339249 |
| NRP1 | neuropilin 1 | -0.0334432 |
| RNF24 | ring finger protein 24 | -0.0332432 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.032566 |
| TMSB4X | thymosin beta 4, X-linked | -0.0325574 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0322133 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0321285 |
| SFTPA2 | surfactant protein A2 | -0.0313809 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0303848 |
| TAGLN2 | transgelin 2 | -0.0300463 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.029916 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0295646 |
| RBM25 | RNA binding motif protein 25 | -0.0295241 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293706 |
| S100A9 | S100 calcium binding protein A9 | -0.0290191 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0286719 |
| RPL35A | ribosomal protein L35a | -0.0285646 |
| RPL37 | ribosomal protein L37 | -0.028206 |
| RPL23 | ribosomal protein L23 | -0.0281667 |
| ENO1 | enolase 1, (alpha) | -0.0278722 |
| CD44 | CD44 molecule (Indian blood group) | -0.0278046 |
| EFNA5 | ephrin-A5 | -0.0275287 |
| RPL31 | ribosomal protein L31 | -0.0271419 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0268716 |
| ASPH | aspartate beta-hydroxylase | -0.0267145 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0266899 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0263534 |
| HLA-A | major histocompatibility complex, class I, A | -0.026213 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0262126 |
| RPS24 | ribosomal protein S24 | -0.0261249 |
| RLF | rearranged L-myc fusion | -0.0261127 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0257908 |
| MAP1B | microtubule-associated protein 1B | -0.0257374 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0253667 |
| COG5 | component of oligomeric golgi complex 5 | -0.0253395 |
| CTSB | cathepsin B | -0.0251559 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0251242 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0243763 |
| CALU | calumenin | -0.024189 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.024105 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0239648 |
| LDHA | lactate dehydrogenase A | -0.0239076 |
| RPS13 | ribosomal protein S13 | -0.0238736 |
| PCM1 | pericentriolar material 1 | -0.0235908 |
| RPS23 | ribosomal protein S23 | -0.0235395 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0231513 |
| MEF2A | myocyte enhancer factor 2A | -0.0231165 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0228417 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0226659 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0226264 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.022579 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0224833 |
| SSR1 | signal sequence receptor, alpha | -0.0224712 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0222534 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.0221595 |
| CFDP1 | craniofacial development protein 1 | -0.0221121 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.022082 |
| KLHDC10 | kelch domain containing 10 | -0.0220058 |
