| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temsirolimus perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Temsirolimus_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0774707 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0719815 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0545147 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0532263 |
| MYO9B | myosin IXB | 0.0398204 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0376578 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0360562 |
| COL5A1 | collagen, type V, alpha 1 | 0.0350589 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.033416 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0327013 |
| RBM6 | RNA binding motif protein 6 | 0.0307502 |
| DNER | delta/notch-like EGF repeat containing | 0.0307439 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0305817 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0277795 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0277297 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0271739 |
| FMNL2 | formin-like 2 | 0.0270276 |
| CAPRIN2 | caprin family member 2 | 0.0269493 |
| POTEF | POTE ankyrin domain family, member F | 0.0265686 |
| NDRG1 | N-myc downstream regulated 1 | 0.0265135 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0257632 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0254148 |
| FN1 | fibronectin 1 | 0.0253214 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0253108 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0251207 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0245391 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0242904 |
| TGM2 | transglutaminase 2 | 0.0242571 |
| GPC5 | glypican 5 | 0.0242295 |
| IGF2 | insulin-like growth factor 2 | 0.02422 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0234735 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0229746 |
| VEGFA | vascular endothelial growth factor A | 0.022758 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0225997 |
| RIN2 | Ras and Rab interactor 2 | 0.0224865 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0222101 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0216853 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0214952 |
| FOSL1 | FOS-like antigen 1 | 0.0207441 |
| PODXL | podocalyxin-like | 0.020401 |
| AREG | amphiregulin | 0.0203419 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0203248 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0202022 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0200813 |
| ANKRD37 | ankyrin repeat domain 37 | 0.02003 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 | 0.0198576 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0197339 |
| PCM1 | pericentriolar material 1 | 0.0194777 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0192881 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0188801 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0185804 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0184344 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0183496 |
| SLC35F2 | solute carrier family 35, member F2 | 0.0183121 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0182924 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | 0.0181191 |
| MT2A | metallothionein 2A | 0.0179059 |
| JAZF1 | JAZF zinc finger 1 | 0.0178276 |
| STK39 | serine threonine kinase 39 | 0.0177383 |
| ATG5 | autophagy related 5 | 0.0177289 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0177162 |
| LAMB1 | laminin, beta 1 | 0.0177049 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0176103 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0174333 |
| SNX25 | sorting nexin 25 | 0.0171589 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0171193 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0170514 |
| RAB31 | RAB31, member RAS oncogene family | 0.0169417 |
| TTC1 | tetratricopeptide repeat domain 1 | 0.0169012 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.016863 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0168575 |
| GSE1 | Gse1 coiled-coil protein | 0.0167872 |
| SATB2 | SATB homeobox 2 | 0.0167561 |
| DSE | dermatan sulfate epimerase | 0.0167408 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0167221 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0165882 |
| SYNRG | synergin, gamma | 0.0165599 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0165342 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0165145 |
| EHD4 | EH-domain containing 4 | 0.016383 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0162516 |
| SMIM44 | small integral membrane protein 44 | 0.0162245 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0161903 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.0161074 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0160757 |
| ISCA1 | iron-sulfur cluster assembly 1 | 0.0160581 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.016048 |
| PLEC | plectin | 0.0160387 |
| KIF1B | kinesin family member 1B | 0.0159653 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0157598 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | 0.0157101 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0156828 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0156552 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.0156518 |
| RNF217 | ring finger protein 217 | 0.0156122 |
| SKIL | SKI-like proto-oncogene | 0.0155118 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0155092 |
| C1D | C1D nuclear receptor corepressor | 0.0154525 |
| DISC1 | disrupted in schizophrenia 1 | 0.0154393 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0154352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.155568 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0998973 |
| SMYD3 | SET and MYND domain containing 3 | -0.0886142 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0842895 |
| NAV2 | neuron navigator 2 | -0.0842179 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0792124 |
| LDHA | lactate dehydrogenase A | -0.0751907 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0749936 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0704636 |
| RBM39 | RNA binding motif protein 39 | -0.0688147 |
| DST | dystonin | -0.0631981 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0628641 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.06197 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0578355 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0566936 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0564324 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0560485 |
| CANX | calnexin | -0.0538213 |
| TPX2 | TPX2, microtubule-associated | -0.0523254 |
| ATM | ATM serine/threonine kinase | -0.0520178 |
| GNAS | GNAS complex locus | -0.0516228 |
| RAD51B | RAD51 paralog B | -0.0514997 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0514694 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0513932 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0509505 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0501874 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0487685 |
| ACER3 | alkaline ceramidase 3 | -0.0485418 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0483804 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0470887 |
| PTMA | prothymosin, alpha | -0.0464461 |
| GOLGA4 | golgin A4 | -0.0463796 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0462169 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0461429 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0459276 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0456928 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0453036 |
| EXOC4 | exocyst complex component 4 | -0.0449332 |
| HMGA2 | high mobility group AT-hook 2 | -0.0445173 |
| RPS3 | ribosomal protein S3 | -0.043542 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0434004 |
| CENPF | centromere protein F, 350/400kDa | -0.0432851 |
| ZNF292 | zinc finger protein 292 | -0.0428061 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.042666 |
| RSF1 | remodeling and spacing factor 1 | -0.0424905 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0423796 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.041889 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0418808 |
| RPLP1 | ribosomal protein, large, P1 | -0.0417279 |
| NAV3 | neuron navigator 3 | -0.0412413 |
| PRSS23 | protease, serine, 23 | -0.0411221 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0411068 |
| MATR3 | matrin 3 | -0.0408773 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0407819 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0406481 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0393794 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.039079 |
| ETNK1 | ethanolamine kinase 1 | -0.0390664 |
| DIAPH3 | diaphanous-related formin 3 | -0.0384644 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0383105 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0382686 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0378984 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0376511 |
| SPAG9 | sperm associated antigen 9 | -0.0374227 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0372894 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0366517 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0364803 |
| OSMR | oncostatin M receptor | -0.0358176 |
| AK1 | adenylate kinase 1 | -0.035794 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0356724 |
| RPL19 | ribosomal protein L19 | -0.0354812 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0353762 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0353209 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0352609 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0352517 |
| GPC6 | glypican 6 | -0.0350345 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0349969 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.03486 |
| AHNAK | AHNAK nucleoprotein | -0.0346136 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0344577 |
| VCL | vinculin | -0.0343112 |
| NKTR | natural killer cell triggering receptor | -0.0341628 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0341108 |
| IL6ST | interleukin 6 signal transducer | -0.0340506 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0339865 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0339509 |
| PGK1 | phosphoglycerate kinase 1 | -0.0338635 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0335438 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0333622 |
| TNPO1 | transportin 1 | -0.0330255 |
| PTK2 | protein tyrosine kinase 2 | -0.0324573 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.032457 |
| FUS | FUS RNA binding protein | -0.0324338 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0321878 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0321558 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0321534 |
| KIF5B | kinesin family member 5B | -0.0320883 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0314542 |
| NUP153 | nucleoporin 153kDa | -0.0311897 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0305079 |
