| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temuterkib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLE4 | transducin-like enhancer of split 4 | 0.0487193 |
| RIGI | RNA sensor RIG-I | 0.0429607 |
| FMN1 | formin 1 | 0.0417917 |
| DST | dystonin | 0.0387969 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.036089 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0353007 |
| ATXN1 | ataxin 1 | 0.0350455 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0339654 |
| SMYD3 | SET and MYND domain containing 3 | 0.0334701 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0323529 |
| VCL | vinculin | 0.0322119 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0313916 |
| PLPP1 | phospholipid phosphatase 1 | 0.030866 |
| DNM3 | dynamin 3 | 0.0294827 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0292172 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0287081 |
| TRIB2 | tribbles pseudokinase 2 | 0.0282278 |
| EXOC4 | exocyst complex component 4 | 0.028113 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0273773 |
| GLCCI1 | glucocorticoid induced 1 | 0.0273446 |
| SEPTIN9 | septin 9 | 0.026877 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0265141 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0261492 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0260767 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0258579 |
| RNF213 | ring finger protein 213 | 0.0253974 |
| FAM107B | family with sequence similarity 107, member B | 0.0250716 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0249499 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.024165 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0239481 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0236135 |
| AMOTL1 | angiomotin like 1 | 0.0229237 |
| LDHA | lactate dehydrogenase A | 0.0227269 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0224306 |
| VGF | VGF nerve growth factor inducible | 0.0222312 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0220548 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0220331 |
| SP100 | SP100 nuclear antigen | 0.0218573 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0218414 |
| GAB2 | GRB2-associated binding protein 2 | 0.0215972 |
| APP | amyloid beta (A4) precursor protein | 0.021375 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0212953 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0212185 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0212017 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0210915 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0209926 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0209912 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0208706 |
| SMAD3 | SMAD family member 3 | 0.0206838 |
| MEIS2 | Meis homeobox 2 | 0.0203981 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0203156 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0200586 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0197528 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0194761 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0191138 |
| ADAR | adenosine deaminase, RNA-specific | 0.0190666 |
| IL6ST | interleukin 6 signal transducer | 0.0190378 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0188989 |
| HELZ | helicase with zinc finger | 0.0187366 |
| KLHL13 | kelch-like family member 13 | 0.0186746 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0186432 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0184511 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0184282 |
| RET | ret proto-oncogene | 0.0184091 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0183461 |
| TPM1 | tropomyosin 1 (alpha) | 0.018068 |
| PDE10A | phosphodiesterase 10A | 0.0180373 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0179309 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0177909 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0175591 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0173825 |
| ZNF521 | zinc finger protein 521 | 0.0172924 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0172712 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0170895 |
| NPAS3 | neuronal PAS domain protein 3 | 0.016948 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0169275 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0168329 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0167705 |
| ITGAV | integrin, alpha V | 0.016676 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0164039 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0163295 |
| GPC6 | glypican 6 | 0.0162456 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0161449 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0159524 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0159188 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0158771 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0158694 |
| MX2 | MX dynamin-like GTPase 2 | 0.0158551 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0157724 |
| COG5 | component of oligomeric golgi complex 5 | 0.0156 |
| LAMB1 | laminin, beta 1 | 0.0155273 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0155015 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0154826 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0153712 |
| TENM4 | teneurin transmembrane protein 4 | 0.015276 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0152739 |
| MSI2 | musashi RNA-binding protein 2 | 0.0152583 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0151717 |
| CANX | calnexin | 0.0151663 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0150972 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.203369 |
| IGF2 | insulin-like growth factor 2 | -0.188758 |
| PTMA | prothymosin, alpha | -0.0788888 |
| VIM | vimentin | -0.0463421 |
| RPL19 | ribosomal protein L19 | -0.0453822 |
| RPS6 | ribosomal protein S6 | -0.0404036 |
| B2M | beta-2-microglobulin | -0.0396741 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0385936 |
| CADM2 | cell adhesion molecule 2 | -0.0385195 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0380436 |
| RPS12 | ribosomal protein S12 | -0.0362048 |
| RPL35A | ribosomal protein L35a | -0.0354304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0354253 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0346546 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0327245 |
| ENAH | enabled homolog (Drosophila) | -0.0325171 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0323248 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0317972 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0312034 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0286656 |
| CRH | corticotropin releasing hormone | -0.0286622 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282257 |
| RPS24 | ribosomal protein S24 | -0.028134 |
| PLAT | plasminogen activator, tissue | -0.0274036 |
| EGR1 | early growth response 1 | -0.0269238 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0268405 |
| GPC5 | glypican 5 | -0.0267384 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0261594 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0253209 |
| ACTG1 | actin gamma 1 | -0.0245571 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0244229 |
| DPH6 | diphthamine biosynthesis 6 | -0.0243799 |
| RPL23 | ribosomal protein L23 | -0.0242547 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0240502 |
| RPLP0 | ribosomal protein, large, P0 | -0.0239254 |
| RPL36 | ribosomal protein L36 | -0.0238763 |
| RPL34 | ribosomal protein L34 | -0.0224576 |
| VEGFA | vascular endothelial growth factor A | -0.0224461 |
| CUX1 | cut-like homeobox 1 | -0.0224194 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0223119 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0222186 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0221006 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0214892 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0214887 |
| IER3 | immediate early response 3 | -0.0213007 |
| FTL | ferritin, light polypeptide | -0.0212129 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0210221 |
| RPS23 | ribosomal protein S23 | -0.0206507 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0202907 |
| LSAMP | limbic system-associated membrane protein | -0.0200075 |
| MBTD1 | mbt domain containing 1 | -0.0198952 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0198347 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0196009 |
| SEPTIN7 | septin 7 | -0.0189249 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0188399 |
| RAB7A | RAB7A, member RAS oncogene family | -0.018822 |
| RO60 | Ro60, Y RNA binding protein | -0.0187685 |
| SETD5 | SET domain containing 5 | -0.0187421 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0185734 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0184622 |
| FAM162A | family with sequence similarity 162, member A | -0.0182194 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0182135 |
| S100A9 | S100 calcium binding protein A9 | -0.0178808 |
| PLCB4 | phospholipase C, beta 4 | -0.0178477 |
| NDRG1 | N-myc downstream regulated 1 | -0.0176617 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0174784 |
| ARF1 | ADP-ribosylation factor 1 | -0.0172819 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0171454 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0171116 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0169115 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0167946 |
| LMNA | lamin A/C | -0.0167713 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0166463 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0165399 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0165286 |
| RPL18 | ribosomal protein L18 | -0.0164355 |
| RPL12 | ribosomal protein L12 | -0.0164142 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0163787 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0162287 |
| CDC27 | cell division cycle 27 | -0.0161462 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0160363 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0159879 |
| RPL32 | ribosomal protein L32 | -0.0159782 |
| TMSB10 | thymosin beta 10 | -0.0158897 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0157793 |
| SCFD1 | sec1 family domain containing 1 | -0.0157484 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0156384 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0155455 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0155163 |
| COL3A1 | collagen, type III, alpha 1 | -0.0154676 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0153017 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.015261 |
| RPS11 | ribosomal protein S11 | -0.0152323 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0152148 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0151937 |
| DTNA | dystrobrevin, alpha | -0.0151778 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -0.0151421 |
| RPL37A | ribosomal protein L37a | -0.0151349 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0151155 |
| USP8 | ubiquitin specific peptidase 8 | -0.0151071 |
