| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temuterkib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.233021 |
| ANXA2 | annexin A2 | 0.0836441 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0710386 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0706034 |
| AREG | amphiregulin | 0.0653879 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0621257 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0598141 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0549103 |
| SMAD3 | SMAD family member 3 | 0.0501596 |
| PLSCR2 | phospholipid scramblase 2 | 0.042892 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0426292 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.039974 |
| PHF3 | PHD finger protein 3 | 0.0398974 |
| PRELID2 | PRELI domain containing 2 | 0.0360025 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.034908 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0348461 |
| FAT1 | FAT atypical cadherin 1 | 0.0341836 |
| SQSTM1 | sequestosome 1 | 0.0334286 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0332392 |
| TOX3 | TOX high mobility group box family member 3 | 0.0331157 |
| KYNU | kynureninase | 0.0305502 |
| DSPP | dentin sialophosphoprotein | 0.0296162 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0290133 |
| USP53 | ubiquitin specific peptidase 53 | 0.0283628 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0280932 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0271387 |
| SDC4 | syndecan 4 | 0.0256861 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0254403 |
| MYO1E | myosin IE | 0.0250413 |
| LAMB3 | laminin, beta 3 | 0.0241564 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0241454 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.023719 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.022854 |
| DST | dystonin | 0.0225391 |
| DUSP10 | dual specificity phosphatase 10 | 0.0220739 |
| EREG | epiregulin | 0.0218784 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0212139 |
| ASPH | aspartate beta-hydroxylase | 0.0211443 |
| RNF43 | ring finger protein 43 | 0.0209052 |
| ANO6 | anoctamin 6 | 0.0206351 |
| VMP1 | vacuole membrane protein 1 | 0.0203209 |
| YAP1 | Yes-associated protein 1 | 0.0201451 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.02007 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0199452 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0199333 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0198003 |
| DSG2 | desmoglein 2 | 0.0193141 |
| EXT1 | exostosin glycosyltransferase 1 | 0.019313 |
| EFNB2 | ephrin-B2 | 0.0192797 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0192641 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0191289 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0191076 |
| IFNGR1 | interferon gamma receptor 1 | 0.0190984 |
| ANXA1 | annexin A1 | 0.0183593 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0180529 |
| CTBP2 | C-terminal binding protein 2 | 0.017949 |
| AEBP2 | AE binding protein 2 | 0.0177156 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0176347 |
| RBM39 | RNA binding motif protein 39 | 0.0175812 |
| OGA | O-GlcNAcase | 0.0175152 |
| FRMD5 | FERM domain containing 5 | 0.0174616 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0173728 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0170082 |
| USP54 | ubiquitin specific peptidase 54 | 0.016914 |
| NEBL | nebulette | 0.016746 |
| EZR | ezrin | 0.0166263 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | 0.0165949 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0164447 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0161507 |
| MLPH | melanophilin | 0.0161297 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0160885 |
| AHNAK | AHNAK nucleoprotein | 0.0160649 |
| RUNX1 | runt-related transcription factor 1 | 0.0159014 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0157288 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0155453 |
| TPR | translocated promoter region, nuclear basket protein | 0.0153833 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0152777 |
| SDCBP | syndecan binding protein (syntenin) | 0.0150737 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0148838 |
| LAMC2 | laminin, gamma 2 | 0.014881 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0148309 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0147341 |
| CLDN12 | claudin 12 | 0.0146786 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0145167 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0144034 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0141942 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.014105 |
| CTSB | cathepsin B | 0.0139678 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0136996 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0136802 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0136075 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0135361 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0135349 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0134448 |
| RYK | receptor-like tyrosine kinase | 0.0134036 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0133973 |
| TMEM65 | transmembrane protein 65 | 0.0133401 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0133143 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0132893 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0132861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LYZ | lysozyme | -0.143089 |
| LCN2 | lipocalin 2 | -0.133433 |
| B2M | beta-2-microglobulin | -0.115816 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.105244 |
| PTMA | prothymosin, alpha | -0.095626 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0943135 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0845267 |
| TXNIP | thioredoxin interacting protein | -0.0820218 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0770732 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0750881 |
| HLA-B | major histocompatibility complex, class I, B | -0.0736768 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0691287 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0668033 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0603304 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0572198 |
| RPL35A | ribosomal protein L35a | -0.0569339 |
| MX1 | MX dynamin-like GTPase 1 | -0.053237 |
| EGR1 | early growth response 1 | -0.0528829 |
| TMSB10 | thymosin beta 10 | -0.0505663 |
| RPS6 | ribosomal protein S6 | -0.0499836 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0468717 |
| MX2 | MX dynamin-like GTPase 2 | -0.0464125 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0453762 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0440013 |
| FTL | ferritin, light polypeptide | -0.0436343 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0426787 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0426383 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0412038 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0406386 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0406198 |
| ERBIN | erbb2 interacting protein | -0.0400985 |
| HLA-A | major histocompatibility complex, class I, A | -0.0385553 |
| TAOK3 | TAO kinase 3 | -0.0377859 |
| PRKCA | protein kinase C, alpha | -0.0376677 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0372067 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0370918 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0369467 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0362962 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0360329 |
| RPL34 | ribosomal protein L34 | -0.035632 |
| TNS4 | tensin 4 | -0.0355763 |
| RPL23 | ribosomal protein L23 | -0.0353691 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0348284 |
| RIGI | RNA sensor RIG-I | -0.0344523 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0340264 |
| EPHB2 | EPH receptor B2 | -0.0337421 |
| AHI1 | Abelson helper integration site 1 | -0.0336663 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0334603 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0332391 |
| PMP22 | peripheral myelin protein 22 | -0.0331111 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0330149 |
| NPSR1 | neuropeptide S receptor 1 | -0.0328226 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.032354 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0318148 |
| TMC5 | transmembrane channel-like 5 | -0.0317483 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0313749 |
| ACTG1 | actin gamma 1 | -0.0309753 |
| RPS27 | ribosomal protein S27 | -0.0307567 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0305551 |
| DSTN | destrin (actin depolymerizing factor) | -0.0305273 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0298328 |
| SP100 | SP100 nuclear antigen | -0.029781 |
| PKM | pyruvate kinase, muscle | -0.0297777 |
| RPS19 | ribosomal protein S19 | -0.029723 |
| IRS2 | insulin receptor substrate 2 | -0.0296708 |
| RPS8 | ribosomal protein S8 | -0.0294998 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0292265 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0291433 |
| CST3 | cystatin C | -0.0288417 |
| S100A9 | S100 calcium binding protein A9 | -0.028586 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0283798 |
| LIMA1 | LIM domain and actin binding 1 | -0.0283511 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280717 |
| UBXN4 | UBX domain protein 4 | -0.0279602 |
| POTEF | POTE ankyrin domain family, member F | -0.0279458 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0274442 |
| ZNF609 | zinc finger protein 609 | -0.0268129 |
| KRT19 | keratin 19, type I | -0.0262255 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0261474 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0260602 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0258506 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.025606 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0254955 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0251793 |
| NBR1 | neighbor of BRCA1 gene 1 | -0.0251418 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0251324 |
| RPL12 | ribosomal protein L12 | -0.0250088 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0248107 |
| ATP11A | ATPase, class VI, type 11A | -0.0246924 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0245226 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.024458 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0244071 |
| RPS23 | ribosomal protein S23 | -0.0241345 |
| BMP4 | bone morphogenetic protein 4 | -0.0241324 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0240195 |
| RPS29 | ribosomal protein S29 | -0.0238762 |
| RPL11 | ribosomal protein L11 | -0.0237165 |
| NDRG1 | N-myc downstream regulated 1 | -0.0236038 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0235982 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0234823 |
