| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temuterkib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.0599577 |
| DST | dystonin | 0.0532879 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0524877 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.040247 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0393077 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0390351 |
| VCL | vinculin | 0.0384188 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.037674 |
| AOPEP | aminopeptidase O (putative) | 0.0350225 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0335733 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0326156 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.030412 |
| BLCAP | bladder cancer associated protein | 0.0300143 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0297219 |
| PLEC | plectin | 0.0278998 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0265693 |
| SMAD3 | SMAD family member 3 | 0.0261819 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0257745 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0251195 |
| MTAP | methylthioadenosine phosphorylase | 0.0250559 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0244358 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0244033 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0243488 |
| MSN | moesin | 0.0241201 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0234174 |
| RASAL2 | RAS protein activator like 2 | 0.0233368 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0232705 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0223075 |
| PRELID2 | PRELI domain containing 2 | 0.0222898 |
| ASPH | aspartate beta-hydroxylase | 0.0219112 |
| FOXO1 | forkhead box O1 | 0.0209848 |
| NEK7 | NIMA-related kinase 7 | 0.0208307 |
| CLIC4 | chloride intracellular channel 4 | 0.0205243 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0203785 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0202734 |
| LUZP1 | leucine zipper protein 1 | 0.0202664 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0197625 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0195908 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0188111 |
| SULF1 | sulfatase 1 | 0.0181494 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0179827 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0179619 |
| RIN2 | Ras and Rab interactor 2 | 0.0179087 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.017834 |
| CORO2A | coronin, actin binding protein, 2A | 0.0177575 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0176737 |
| RIGI | RNA sensor RIG-I | 0.0175282 |
| TPM3 | tropomyosin 3 | 0.0173725 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0172265 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0171678 |
| DNAJC18 | DnaJ (Hsp40) homolog, subfamily C, member 18 | 0.0171126 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.0168914 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | 0.0168719 |
| AMOTL1 | angiomotin like 1 | 0.0168057 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0167423 |
| KIAA1671 | KIAA1671 | 0.0166075 |
| SMYD3 | SET and MYND domain containing 3 | 0.0165335 |
| SEPTIN9 | septin 9 | 0.0165033 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0164117 |
| SERTAD2 | SERTA domain containing 2 | 0.0162234 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | 0.0161041 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0159013 |
| SETX | senataxin | 0.0158679 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0158364 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0157852 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0157727 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0157027 |
| DOK5 | docking protein 5 | 0.0154469 |
| PCM1 | pericentriolar material 1 | 0.0150954 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0149645 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0149247 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0148131 |
| ZNF644 | zinc finger protein 644 | 0.0146757 |
| KIAA0040 | KIAA0040 | 0.014653 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0146395 |
| FN1 | fibronectin 1 | 0.0144877 |
| SETBP1 | SET binding protein 1 | 0.01441 |
| UBAP2 | ubiquitin associated protein 2 | 0.0143482 |
| MYOF | myoferlin | 0.0140773 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0139584 |
| IL6ST | interleukin 6 signal transducer | 0.0138033 |
| HMGA2 | high mobility group AT-hook 2 | 0.0137533 |
| MRTFA | myocardin related transcription factor A | 0.01357 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.0133607 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0133345 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0133257 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0132855 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0131923 |
| FAM168A | family with sequence similarity 168, member A | 0.0131877 |
| BCL2L1 | BCL2-like 1 | 0.0131775 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0131774 |
| JAK2 | Janus kinase 2 | 0.0131291 |
| SULF2 | sulfatase 2 | 0.0130794 |
| CTBP2 | C-terminal binding protein 2 | 0.0130742 |
| PLXNA2 | plexin A2 | 0.0130313 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0130295 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0130101 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.0129999 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0128725 |
| CUL4B | cullin 4B | 0.0126838 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.267238 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130034 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.129993 |
| TMSB10 | thymosin beta 10 | -0.125503 |
| MT2A | metallothionein 2A | -0.113447 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101321 |
| NDRG1 | N-myc downstream regulated 1 | -0.0999711 |
| RPS21 | ribosomal protein S21 | -0.0975115 |
| B2M | beta-2-microglobulin | -0.0924631 |
| PTMA | prothymosin, alpha | -0.082794 |
| RPS6 | ribosomal protein S6 | -0.0799077 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0783201 |
| RPS8 | ribosomal protein S8 | -0.0776107 |
| RPS3 | ribosomal protein S3 | -0.0728282 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0726992 |
| HLA-B | major histocompatibility complex, class I, B | -0.0710347 |
| RPLP2 | ribosomal protein, large, P2 | -0.0681713 |
| RPLP1 | ribosomal protein, large, P1 | -0.0648832 |
| MTSS1 | metastasis suppressor 1 | -0.0641182 |
| RPS13 | ribosomal protein S13 | -0.063658 |
| RPS19 | ribosomal protein S19 | -0.0623073 |
| LDHA | lactate dehydrogenase A | -0.061561 |
| S100A10 | S100 calcium binding protein A10 | -0.0592124 |
| RPL11 | ribosomal protein L11 | -0.0591521 |
| TMSB4X | thymosin beta 4, X-linked | -0.0584159 |
| RPL34 | ribosomal protein L34 | -0.0559098 |
| RPL12 | ribosomal protein L12 | -0.0557363 |
| RPL23 | ribosomal protein L23 | -0.0546865 |
| FLNB | filamin B, beta | -0.054562 |
| ENO1 | enolase 1, (alpha) | -0.0535896 |
| RPL37 | ribosomal protein L37 | -0.0522234 |
| RPL31 | ribosomal protein L31 | -0.0509759 |
| FTL | ferritin, light polypeptide | -0.0500135 |
| RPL26 | ribosomal protein L26 | -0.0495852 |
| RPS12 | ribosomal protein S12 | -0.049414 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0462214 |
| LMNA | lamin A/C | -0.0454904 |
| RPL8 | ribosomal protein L8 | -0.0451697 |
| CLU | clusterin | -0.04512 |
| RPL19 | ribosomal protein L19 | -0.0434549 |
| S100A9 | S100 calcium binding protein A9 | -0.0432959 |
| RPL35A | ribosomal protein L35a | -0.0429514 |
| RPS24 | ribosomal protein S24 | -0.0421246 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0412853 |
| RPL36 | ribosomal protein L36 | -0.0412266 |
| POTEF | POTE ankyrin domain family, member F | -0.0406762 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0401248 |
| S100A6 | S100 calcium binding protein A6 | -0.0390016 |
| S100A11 | S100 calcium binding protein A11 | -0.0388427 |
| RPS25 | ribosomal protein S25 | -0.038226 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0374773 |
| RPL37A | ribosomal protein L37a | -0.0373131 |
| RPS27 | ribosomal protein S27 | -0.0372756 |
| S100A2 | S100 calcium binding protein A2 | -0.0369555 |
| KRT17 | keratin 17, type I | -0.0368053 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0362631 |
| RPL35 | ribosomal protein L35 | -0.0360415 |
| IGF2 | insulin-like growth factor 2 | -0.035952 |
| H1-0 | H1.0 linker histone | -0.0357814 |
| RPL32 | ribosomal protein L32 | -0.0353782 |
| RPS23 | ribosomal protein S23 | -0.0352342 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0349331 |
| GNAS | GNAS complex locus | -0.0341279 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0335607 |
| RPL9 | ribosomal protein L9 | -0.0333094 |
| MT1X | metallothionein 1X | -0.03298 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0323371 |
| RPS14 | ribosomal protein S14 | -0.0323194 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0322623 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0321373 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0318876 |
| RPL30 | ribosomal protein L30 | -0.0318385 |
| RPLP0 | ribosomal protein, large, P0 | -0.0317023 |
| RACK1 | receptor for activated C kinase 1 | -0.0315282 |
| CSTB | cystatin B (stefin B) | -0.0312131 |
| RPL5 | ribosomal protein L5 | -0.0310187 |
| RPS4X | ribosomal protein S4, X-linked | -0.0308287 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0307444 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0305727 |
| RPL36A | ribosomal protein L36a | -0.0303724 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0301036 |
| CD44 | CD44 molecule (Indian blood group) | -0.0299089 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0298813 |
| EMP1 | epithelial membrane protein 1 | -0.0298572 |
| RPL27A | ribosomal protein L27a | -0.0296691 |
| PGK1 | phosphoglycerate kinase 1 | -0.0294693 |
| GOLGA4 | golgin A4 | -0.0289279 |
| MT1E | metallothionein 1E | -0.0284719 |
| RPL18 | ribosomal protein L18 | -0.0283183 |
| STC1 | stanniocalcin 1 | -0.0278962 |
| YBX3 | Y box binding protein 3 | -0.0278458 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0271469 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0267386 |
| PFN1 | profilin 1 | -0.0265868 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.026536 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262959 |
| PODXL | podocalyxin-like | -0.0261858 |
| IFI44L | interferon-induced protein 44-like | -0.0260983 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0257734 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.025737 |
