| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Temuterkib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.144044 |
| FNDC3B | fibronectin type III domain containing 3B | 0.10261 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0915851 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.090459 |
| SMAD3 | SMAD family member 3 | 0.0880463 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0855308 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0792565 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0792381 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0722861 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0716325 |
| FN1 | fibronectin 1 | 0.0706375 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0657455 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.059146 |
| EFNA5 | ephrin-A5 | 0.0591003 |
| RAD51B | RAD51 paralog B | 0.0572591 |
| NAV2 | neuron navigator 2 | 0.056373 |
| ATXN1 | ataxin 1 | 0.056152 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0551727 |
| EGFR | epidermal growth factor receptor | 0.0532329 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0509279 |
| ASPH | aspartate beta-hydroxylase | 0.050553 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0498827 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0494358 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0489732 |
| HMGA2 | high mobility group AT-hook 2 | 0.0466949 |
| NTN4 | netrin 4 | 0.0459638 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0454769 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0452624 |
| MYO10 | myosin X | 0.0442624 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0439668 |
| FAM20C | family with sequence similarity 20, member C | 0.0434091 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0413494 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0399489 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0393726 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0392793 |
| KYNU | kynureninase | 0.0389924 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0385695 |
| DST | dystonin | 0.0382686 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0380931 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0377712 |
| SYT1 | synaptotagmin I | 0.0377543 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0372187 |
| PRKCA | protein kinase C, alpha | 0.0363652 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0357863 |
| SVIL | supervillin | 0.0352481 |
| VCL | vinculin | 0.035099 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0347725 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0343051 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0342162 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0340176 |
| FAM107B | family with sequence similarity 107, member B | 0.0329521 |
| ANO6 | anoctamin 6 | 0.0325199 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0325046 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0323359 |
| TGM2 | transglutaminase 2 | 0.0322481 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0322051 |
| GLCCI1 | glucocorticoid induced 1 | 0.0317899 |
| AHNAK | AHNAK nucleoprotein | 0.0313867 |
| ECE1 | endothelin converting enzyme 1 | 0.0312267 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0306435 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0300103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0293043 |
| SEPTIN9 | septin 9 | 0.0292216 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0288625 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0288372 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0285215 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0284818 |
| STK38L | serine/threonine kinase 38 like | 0.0276957 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0274656 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0272474 |
| LOX | lysyl oxidase | 0.027199 |
| NAV1 | neuron navigator 1 | 0.0271357 |
| LOXL2 | lysyl oxidase-like 2 | 0.0271046 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0270797 |
| ZNF804A | zinc finger protein 804A | 0.026832 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0266062 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0265233 |
| KSR1 | kinase suppressor of ras 1 | 0.0263774 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0263145 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0262265 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0259066 |
| LDHA | lactate dehydrogenase A | 0.0258336 |
| WLS | wntless Wnt ligand secretion mediator | 0.0254413 |
| HDAC4 | histone deacetylase 4 | 0.0253589 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0249467 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0249148 |
| TXNRD1 | thioredoxin reductase 1 | 0.024877 |
| ETV6 | ets variant 6 | 0.0247737 |
| IL6ST | interleukin 6 signal transducer | 0.0247595 |
| EXOC6B | exocyst complex component 6B | 0.0246637 |
| PLEC | plectin | 0.0245065 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0243923 |
| KIAA1217 | KIAA1217 | 0.0243385 |
| CLIC4 | chloride intracellular channel 4 | 0.0239659 |
| CDH13 | cadherin 13 | 0.023919 |
| GPC6 | glypican 6 | 0.0238568 |
| VEGFC | vascular endothelial growth factor C | 0.023828 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0235926 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0235868 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0235219 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.110639 |
| FTL | ferritin, light polypeptide | -0.106668 |
| VIM | vimentin | -0.0957578 |
| GOLGA4 | golgin A4 | -0.0933844 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0848003 |
| STC1 | stanniocalcin 1 | -0.0812136 |
| PTMA | prothymosin, alpha | -0.0729998 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0669332 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0622779 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0615786 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0510917 |
| RIOK3 | RIO kinase 3 | -0.0426448 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0407288 |
| RPS19 | ribosomal protein S19 | -0.0402346 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0391627 |
| SETD5 | SET domain containing 5 | -0.0391407 |
| RPS8 | ribosomal protein S8 | -0.0388301 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0379772 |
| S100A6 | S100 calcium binding protein A6 | -0.0377444 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0376903 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0371047 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0370675 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0367058 |
| RPLP1 | ribosomal protein, large, P1 | -0.0364285 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0358904 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0357706 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0356975 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.035271 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0352191 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0349368 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0349309 |
| B2M | beta-2-microglobulin | -0.0348797 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0346666 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0344124 |
| RPLP0 | ribosomal protein, large, P0 | -0.0337673 |
| FAM13A | family with sequence similarity 13, member A | -0.0335531 |
| NDRG1 | N-myc downstream regulated 1 | -0.0332206 |
| GNAS | GNAS complex locus | -0.032638 |
| USP3 | ubiquitin specific peptidase 3 | -0.031916 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0317988 |
| RBM39 | RNA binding motif protein 39 | -0.0315871 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0304672 |
| RPL35A | ribosomal protein L35a | -0.030397 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0294078 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0291912 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0288228 |
| WDR45B | WD repeat domain 45B | -0.028548 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0285154 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0284627 |
| HMGA1 | high mobility group AT-hook 1 | -0.0281227 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0279379 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0277056 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0276932 |
| SPAG9 | sperm associated antigen 9 | -0.0276718 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0275776 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0274069 |
| RPL37A | ribosomal protein L37a | -0.0273582 |
| RPS3 | ribosomal protein S3 | -0.0271603 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0263523 |
| RPL36 | ribosomal protein L36 | -0.0263168 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0262956 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0262051 |
| RPS6 | ribosomal protein S6 | -0.0261115 |
| FAM162A | family with sequence similarity 162, member A | -0.0254311 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0252509 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0249882 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0244373 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0238793 |
| YBX1 | Y box binding protein 1 | -0.0233807 |
| OGA | O-GlcNAcase | -0.0233769 |
| MEF2A | myocyte enhancer factor 2A | -0.0231645 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0231523 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0229945 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0228748 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0227659 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.022575 |
| SRP54 | signal recognition particle 54kDa | -0.022547 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0224777 |
| RPL18 | ribosomal protein L18 | -0.0223392 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0221687 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0221581 |
| YY1 | YY1 transcription factor | -0.0218869 |
| RPS13 | ribosomal protein S13 | -0.0217652 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0216879 |
| RNF145 | ring finger protein 145 | -0.0214545 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0214263 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0212614 |
| CCDC88A | coiled-coil domain containing 88A | -0.0210279 |
| PFN1 | profilin 1 | -0.0210026 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0209943 |
| RPL11 | ribosomal protein L11 | -0.0208203 |
| DENND4A | DENN/MADD domain containing 4A | -0.020515 |
| NGLY1 | N-glycanase 1 | -0.0204424 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0204304 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0202927 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0202136 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.01988 |
| HIP1 | huntingtin interacting protein 1 | -0.019797 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0196885 |
| RPL26 | ribosomal protein L26 | -0.0196775 |
