| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Temuterkib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.12237 |
| EXT1 | exostosin glycosyltransferase 1 | 0.109789 |
| EFNA5 | ephrin-A5 | 0.103503 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0765594 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0760213 |
| FBXO32 | F-box protein 32 | 0.0670064 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0607596 |
| NDRG1 | N-myc downstream regulated 1 | 0.0574157 |
| NAV2 | neuron navigator 2 | 0.0558361 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0538935 |
| DTNA | dystrobrevin, alpha | 0.0537943 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0532502 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0510195 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0497849 |
| ERBIN | erbb2 interacting protein | 0.0483619 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0447619 |
| MYO1E | myosin IE | 0.0442186 |
| ATXN1 | ataxin 1 | 0.0438792 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0408996 |
| EGFR | epidermal growth factor receptor | 0.0385265 |
| VEGFA | vascular endothelial growth factor A | 0.0377148 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0375145 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0372959 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0371972 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0371417 |
| GOLGB1 | golgin B1 | 0.0371347 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0366171 |
| PLEC | plectin | 0.0361918 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0358338 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0357187 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0350273 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.034969 |
| DSPP | dentin sialophosphoprotein | 0.0349104 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0345581 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.03402 |
| MAP1B | microtubule-associated protein 1B | 0.0334297 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0334012 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0331436 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0326966 |
| VCL | vinculin | 0.0326469 |
| SMAD3 | SMAD family member 3 | 0.0325736 |
| LDHA | lactate dehydrogenase A | 0.0325409 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0324984 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0322223 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0320292 |
| MSN | moesin | 0.0319805 |
| TJP1 | tight junction protein 1 | 0.0319354 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0318423 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0317373 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0316664 |
| OCLN | occludin | 0.0316546 |
| RNF213 | ring finger protein 213 | 0.0316297 |
| MYO5B | myosin VB | 0.0316284 |
| FNIP1 | folliculin interacting protein 1 | 0.0313911 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0312894 |
| RAD51B | RAD51 paralog B | 0.0312567 |
| HDAC9 | histone deacetylase 9 | 0.0311573 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0311508 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0309564 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0308294 |
| CTBP2 | C-terminal binding protein 2 | 0.0305029 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0304177 |
| FHIT | fragile histidine triad | 0.0303671 |
| RUNX1 | runt-related transcription factor 1 | 0.0302374 |
| DUSP10 | dual specificity phosphatase 10 | 0.0296128 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0294505 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.029312 |
| HLA-B | major histocompatibility complex, class I, B | 0.0291748 |
| POTEF | POTE ankyrin domain family, member F | 0.0289048 |
| RCOR1 | REST corepressor 1 | 0.0285752 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0284456 |
| MYO6 | myosin VI | 0.0284257 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0281383 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0280435 |
| VGLL3 | vestigial-like family member 3 | 0.0279851 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278744 |
| RPL23 | ribosomal protein L23 | 0.02774 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0277195 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.027667 |
| PRKCA | protein kinase C, alpha | 0.0273268 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0273225 |
| ARF4 | ADP-ribosylation factor 4 | 0.0272146 |
| FAM107B | family with sequence similarity 107, member B | 0.027198 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271657 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0271138 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0270742 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0268229 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0266176 |
| VMP1 | vacuole membrane protein 1 | 0.0265115 |
| ANO6 | anoctamin 6 | 0.0263745 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0262057 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.026152 |
| PLSCR1 | phospholipid scramblase 1 | 0.0260587 |
| BRD2 | bromodomain containing 2 | 0.0258719 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0255393 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0251734 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.024917 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0247308 |
| TPM3 | tropomyosin 3 | 0.0246892 |
| RPS17 | ribosomal protein S17 | 0.0246439 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.165337 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148601 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.119502 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115002 |
| FTL | ferritin, light polypeptide | -0.113468 |
| S100A6 | S100 calcium binding protein A6 | -0.101089 |
| ASPH | aspartate beta-hydroxylase | -0.0876327 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0870363 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0824281 |
| FN1 | fibronectin 1 | -0.0821234 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0803871 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0725645 |
| ANXA2 | annexin A2 | -0.0675701 |
| S100A10 | S100 calcium binding protein A10 | -0.0652544 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0651734 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0620639 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0616179 |
| PLAU | plasminogen activator, urokinase | -0.0606558 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0590915 |
| CCND1 | cyclin D1 | -0.0587855 |
| GNAS | GNAS complex locus | -0.0576367 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0574563 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0570331 |
| ACTG1 | actin gamma 1 | -0.0543829 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0533973 |
| TFG | TRK-fused gene | -0.0500556 |
| PGK1 | phosphoglycerate kinase 1 | -0.0490857 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0480113 |
| HMGB2 | high mobility group box 2 | -0.0479671 |
| EPCAM | epithelial cell adhesion molecule | -0.0450022 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0446533 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0435335 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0431975 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0423325 |
| TMSB10 | thymosin beta 10 | -0.0416372 |
| HMGA1 | high mobility group AT-hook 1 | -0.041625 |
| RPL8 | ribosomal protein L8 | -0.0411979 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0395302 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0393491 |
| RPL35A | ribosomal protein L35a | -0.0387951 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0369212 |
| RLF | rearranged L-myc fusion | -0.0369015 |
| RNF145 | ring finger protein 145 | -0.0355519 |
| DEK | DEK proto-oncogene | -0.03544 |
| FAM162A | family with sequence similarity 162, member A | -0.0347154 |
| DSTN | destrin (actin depolymerizing factor) | -0.0345813 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0345131 |
| AREG | amphiregulin | -0.034371 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0342491 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0338907 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0338197 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0334259 |
| RHEB | Ras homolog enriched in brain | -0.0330718 |
| TOP1 | topoisomerase (DNA) I | -0.0327557 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0325272 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0321686 |
| LMAN1 | lectin, mannose-binding, 1 | -0.031812 |
| TPM4 | tropomyosin 4 | -0.0315487 |
| LMNA | lamin A/C | -0.0314413 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0313506 |
| ZNF292 | zinc finger protein 292 | -0.0312857 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0309484 |
| CD2AP | CD2-associated protein | -0.0306565 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0303668 |
| CSTB | cystatin B (stefin B) | -0.0301168 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0297135 |
| ANLN | anillin, actin binding protein | -0.0294089 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0292512 |
| TMEM123 | transmembrane protein 123 | -0.0287492 |
| G0S2 | G0/G1 switch 2 | -0.0287135 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0284178 |
| TMEM263 | transmembrane protein 263 | -0.0281119 |
| PRRC1 | proline-rich coiled-coil 1 | -0.027111 |
| RPS24 | ribosomal protein S24 | -0.0270734 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0270601 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0267521 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0264999 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0264668 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.026424 |
| RPS8 | ribosomal protein S8 | -0.0261244 |
| RPL34 | ribosomal protein L34 | -0.0261082 |
| CALU | calumenin | -0.0260951 |
| USP3 | ubiquitin specific peptidase 3 | -0.0259265 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0258187 |
| MXD1 | MAX dimerization protein 1 | -0.0257377 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.025641 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0254294 |
| RPLP1 | ribosomal protein, large, P1 | -0.025288 |
| CCNI | cyclin I | -0.0251674 |
| YBX3 | Y box binding protein 3 | -0.0251098 |
| CALR | calreticulin | -0.0251094 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0250408 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0247261 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0243736 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0242694 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0239771 |
| TMSB4X | thymosin beta 4, X-linked | -0.0237888 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0236947 |
| WTAP | Wilms tumor 1 associated protein | -0.0233079 |
| CD63 | CD63 molecule | -0.0231412 |
