| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Temuterkib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.185266 |
| COL5A2 | collagen, type V, alpha 2 | 0.15429 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.121039 |
| TENM3 | teneurin transmembrane protein 3 | 0.107434 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.106751 |
| NTM | neurotrimin | 0.105926 |
| CADM2 | cell adhesion molecule 2 | 0.0764775 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0663965 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0638568 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.060322 |
| ITGAV | integrin, alpha V | 0.0577504 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0576539 |
| LDHA | lactate dehydrogenase A | 0.0529985 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0511582 |
| COL3A1 | collagen, type III, alpha 1 | 0.0510436 |
| PDGFC | platelet derived growth factor C | 0.0493502 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0428422 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0411888 |
| RAD51B | RAD51 paralog B | 0.0393953 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0371459 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0366112 |
| FOXP2 | forkhead box P2 | 0.0361213 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0358825 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0350377 |
| ENO1 | enolase 1, (alpha) | 0.0350176 |
| CDH19 | cadherin 19, type 2 | 0.0344325 |
| LRRC4C | leucine rich repeat containing 4C | 0.0342227 |
| HDAC9 | histone deacetylase 9 | 0.0342002 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0337302 |
| NHSL1 | NHS-like 1 | 0.0334948 |
| ZNF608 | zinc finger protein 608 | 0.0323222 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0314776 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0304976 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0302793 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0298252 |
| RPS16 | ribosomal protein S16 | 0.0295449 |
| HMGA2 | high mobility group AT-hook 2 | 0.0292157 |
| MPG | N-methylpurine-DNA glycosylase | 0.0291019 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0282416 |
| RPL37 | ribosomal protein L37 | 0.0279538 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0274556 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0273311 |
| PTMA | prothymosin, alpha | 0.0270018 |
| ANK2 | ankyrin 2, neuronal | 0.0267671 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0266292 |
| RPS27A | ribosomal protein S27a | 0.0265001 |
| MKI67 | marker of proliferation Ki-67 | 0.026303 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0262357 |
| LIN28B | lin-28 homolog B (C. elegans) | 0.0260056 |
| RPS8 | ribosomal protein S8 | 0.0256795 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0253186 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0252832 |
| LPIN2 | lipin 2 | 0.0250714 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0250317 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0249898 |
| CCDC138 | coiled-coil domain containing 138 | 0.0243267 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0240877 |
| MCL1 | myeloid cell leukemia 1 | 0.0240148 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0238092 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0236962 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.023454 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0233404 |
| PGK1 | phosphoglycerate kinase 1 | 0.0232514 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0228089 |
| WWC2 | WW and C2 domain containing 2 | 0.0226634 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0226083 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0224111 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0221367 |
| RPL38 | ribosomal protein L38 | 0.0219848 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0217954 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0216074 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0210294 |
| PDS5A | PDS5 cohesin associated factor A | 0.0209413 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0209396 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0206159 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0206143 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0206104 |
| FAT1 | FAT atypical cadherin 1 | 0.0205744 |
| YAP1 | Yes-associated protein 1 | 0.0205454 |
| SCFD1 | sec1 family domain containing 1 | 0.0203727 |
| CLSTN1 | calsyntenin 1 | 0.0201581 |
| RPL11 | ribosomal protein L11 | 0.020105 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0197726 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0196796 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0196613 |
| RBM5 | RNA binding motif protein 5 | 0.0196498 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0195236 |
| AFF1 | AF4/FMR2 family, member 1 | 0.019271 |
| RPL31 | ribosomal protein L31 | 0.0192155 |
| APOE | apolipoprotein E | 0.0188813 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0186693 |
| MGA | MGA, MAX dimerization protein | 0.0186043 |
| FGF12 | fibroblast growth factor 12 | 0.0185717 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0185451 |
| PCNX4 | pecanex 4 | 0.0185102 |
| CANX | calnexin | 0.018349 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0182449 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0182233 |
| RPL36A | ribosomal protein L36a | 0.0182211 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0181934 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0955928 |
| VIM | vimentin | -0.0875971 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0612329 |
| PFN1 | profilin 1 | -0.0508411 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0452649 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0450144 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0443658 |
| PEG10 | paternally expressed 10 | -0.0443516 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0418973 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.041351 |
| TMSB4X | thymosin beta 4, X-linked | -0.0406256 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0386927 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.037942 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0364525 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0343959 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0342679 |
| TCF12 | transcription factor 12 | -0.0330253 |
| RAI1 | retinoic acid induced 1 | -0.0305891 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0296789 |
| EMP1 | epithelial membrane protein 1 | -0.0296263 |
| EZR | ezrin | -0.0294437 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0281945 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0274937 |
| POTEF | POTE ankyrin domain family, member F | -0.0272965 |
| HSPA1A | heat shock 70kDa protein 1A | -0.026276 |
| YBX1 | Y box binding protein 1 | -0.0259141 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0257435 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0255273 |
| ZNF217 | zinc finger protein 217 | -0.0253583 |
| SETD5 | SET domain containing 5 | -0.0251948 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0250652 |
| TPX2 | TPX2, microtubule-associated | -0.024656 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0246026 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0240218 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0239315 |
| RTN4 | reticulon 4 | -0.0237849 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0237422 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0237001 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0230115 |
| MED13L | mediator complex subunit 13-like | -0.0229152 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0228412 |
| TMEM165 | transmembrane protein 165 | -0.0227323 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0224341 |
| FBL | fibrillarin | -0.0222505 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0220327 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0219934 |
| OGA | O-GlcNAcase | -0.0217395 |
| SEPTIN7 | septin 7 | -0.0217106 |
| SLMAP | sarcolemma associated protein | -0.0215571 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0213909 |
| RBM27 | RNA binding motif protein 27 | -0.0213866 |
| TMSB10 | thymosin beta 10 | -0.0210271 |
| ZFR | zinc finger RNA binding protein | -0.0210265 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0208226 |
| CBX3 | chromobox homolog 3 | -0.0207246 |
| CDC73 | cell division cycle 73 | -0.0205735 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0204163 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0204023 |
| RPL32 | ribosomal protein L32 | -0.0203393 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0202734 |
| NOP58 | NOP58 ribonucleoprotein | -0.0202473 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0201866 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0200861 |
| LYPLA1 | lysophospholipase I | -0.0200667 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0198998 |
| FLNB | filamin B, beta | -0.019839 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | -0.0198073 |
| SGO2 | shugoshin 2 | -0.0198018 |
| RANBP9 | RAN binding protein 9 | -0.0197833 |
| RPS6 | ribosomal protein S6 | -0.0196836 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0196003 |
| SRPK2 | SRSF protein kinase 2 | -0.0195526 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0195462 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0195181 |
| RAD21 | RAD21 homolog (S. pombe) | -0.01951 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0193796 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0193608 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0193141 |
| RACK1 | receptor for activated C kinase 1 | -0.0192954 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0191253 |
| RFX7 | regulatory factor X, 7 | -0.018872 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -0.0187372 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0186691 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0185873 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0185575 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0185386 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0183636 |
| GNAS | GNAS complex locus | -0.0183422 |
| FNBP1L | formin binding protein 1-like | -0.0182915 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0182225 |
| TENM2 | teneurin transmembrane protein 2 | -0.0181962 |
| LAMB3 | laminin, beta 3 | -0.0181389 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0181263 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0180307 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0180063 |
| H1-0 | H1.0 linker histone | -0.0179024 |
| MYO6 | myosin VI | -0.017877 |
| TMEM263 | transmembrane protein 263 | -0.0178048 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0177346 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0176818 |
