| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Temuterkib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Temuterkib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0922006 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0652274 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0551276 |
| GLI3 | GLI family zinc finger 3 | 0.0439391 |
| FOXP1 | forkhead box P1 | 0.0316045 |
| HDAC9 | histone deacetylase 9 | 0.0274023 |
| GSE1 | Gse1 coiled-coil protein | 0.0265939 |
| RRM2 | ribonucleotide reductase M2 | 0.026158 |
| ANXA1 | annexin A1 | 0.0260036 |
| MYO5C | myosin VC | 0.0257854 |
| NAV2 | neuron navigator 2 | 0.0257076 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0252914 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0251652 |
| MKI67 | marker of proliferation Ki-67 | 0.0250611 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0250406 |
| FER1L6 | fer-1-like family member 6 | 0.0222635 |
| VCL | vinculin | 0.0214732 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0212841 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0206644 |
| PDGFC | platelet derived growth factor C | 0.019906 |
| MACROD2 | MACRO domain containing 2 | 0.019884 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0197386 |
| PDE7B | phosphodiesterase 7B | 0.0194225 |
| PKM | pyruvate kinase, muscle | 0.0186537 |
| BMP10 | bone morphogenetic protein 10 | 0.0183901 |
| ZNF608 | zinc finger protein 608 | 0.0176304 |
| SEPTIN9 | septin 9 | 0.0175974 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0175586 |
| EGFR | epidermal growth factor receptor | 0.01749 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0171886 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0169865 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0161637 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0160211 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0157863 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0147235 |
| CENPF | centromere protein F, 350/400kDa | 0.0145121 |
| DIAPH3 | diaphanous-related formin 3 | 0.0144787 |
| TJP1 | tight junction protein 1 | 0.0144449 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0143424 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0142202 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0141942 |
| AHNAK | AHNAK nucleoprotein | 0.0141527 |
| PRELID2 | PRELI domain containing 2 | 0.0140448 |
| RPL3 | ribosomal protein L3 | 0.0134655 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0134148 |
| AEBP2 | AE binding protein 2 | 0.0134021 |
| CEP112 | centrosomal protein 112kDa | 0.0133399 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0131779 |
| CUX1 | cut-like homeobox 1 | 0.0130781 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0130565 |
| ASPH | aspartate beta-hydroxylase | 0.0129123 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0128808 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0128232 |
| CEP128 | centrosomal protein 128kDa | 0.0126899 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0126774 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0126205 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.0126106 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0124434 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0123627 |
| RAD51B | RAD51 paralog B | 0.0118911 |
| PRKCE | protein kinase C, epsilon | 0.0118832 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0118805 |
| GLI2 | GLI family zinc finger 2 | 0.011707 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0116637 |
| EXOC4 | exocyst complex component 4 | 0.0116232 |
| MYO9A | myosin IXA | 0.011602 |
| WWOX | WW domain containing oxidoreductase | 0.0115792 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0115364 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0115202 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0113771 |
| TPX2 | TPX2, microtubule-associated | 0.0113323 |
| YAP1 | Yes-associated protein 1 | 0.0113198 |
| POTEF | POTE ankyrin domain family, member F | 0.0113056 |
| CENPP | centromere protein P | 0.0112816 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.011243 |
| MMS22L | MMS22-like, DNA repair protein | 0.010979 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0107175 |
| MLIP | muscular LMNA-interacting protein | 0.0106435 |
| FMN1 | formin 1 | 0.0106254 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.01061 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0105249 |
| INTS6 | integrator complex subunit 6 | 0.0105142 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0104458 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0104264 |
| DST | dystonin | 0.0103622 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0102328 |
| TFDP1 | transcription factor Dp-1 | 0.0101712 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | 0.0101467 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.010123 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0101139 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.0101039 |
| HELLS | helicase, lymphoid-specific | 0.0100714 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0100664 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00998247 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00988353 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.00986714 |
| ITGA6 | integrin, alpha 6 | 0.00971411 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00967802 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00960035 |
| FER | fer (fps/fes related) tyrosine kinase | 0.00958382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125799 |
| PTMA | prothymosin, alpha | -0.124369 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.091822 |
| GOLGA4 | golgin A4 | -0.0647739 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0491386 |
| S100A6 | S100 calcium binding protein A6 | -0.0490306 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.047248 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0458204 |
| RTN4 | reticulon 4 | -0.0453423 |
| ACTG1 | actin gamma 1 | -0.0451392 |
| FLNB | filamin B, beta | -0.0443013 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0397319 |
| RPS8 | ribosomal protein S8 | -0.0387984 |
| RPL35A | ribosomal protein L35a | -0.0371057 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0370645 |
| RPS6 | ribosomal protein S6 | -0.0360446 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0345061 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0311693 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0311223 |
| RPL19 | ribosomal protein L19 | -0.0305083 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0303698 |
| RPS19 | ribosomal protein S19 | -0.0302795 |
| RPL12 | ribosomal protein L12 | -0.0301537 |
| RPL11 | ribosomal protein L11 | -0.0296449 |
| RPL26 | ribosomal protein L26 | -0.0294489 |
| TMSB4X | thymosin beta 4, X-linked | -0.0292881 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0285969 |
| RPL34 | ribosomal protein L34 | -0.0279903 |
| RBM39 | RNA binding motif protein 39 | -0.0278424 |
| RPLP1 | ribosomal protein, large, P1 | -0.0276577 |
| RPL36 | ribosomal protein L36 | -0.0273155 |
| RPL9 | ribosomal protein L9 | -0.0269665 |
| RPLP0 | ribosomal protein, large, P0 | -0.0266887 |
| RPL37A | ribosomal protein L37a | -0.0256224 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0253158 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0247743 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0246088 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0245334 |
| TMEM41B | transmembrane protein 41B | -0.0244113 |
| PFN1 | profilin 1 | -0.0236358 |
| ANK2 | ankyrin 2, neuronal | -0.0234938 |
| RPL13A | ribosomal protein L13a | -0.0234295 |
| GNAS | GNAS complex locus | -0.0233749 |
| RPL32 | ribosomal protein L32 | -0.0230272 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.022945 |
| TXNRD1 | thioredoxin reductase 1 | -0.0228733 |
| ZNF292 | zinc finger protein 292 | -0.0223345 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0221456 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0217825 |
| RPL5 | ribosomal protein L5 | -0.0217112 |
| B2M | beta-2-microglobulin | -0.0215528 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0215498 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0215264 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0213174 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0210658 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0210407 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0209433 |
| RPS3 | ribosomal protein S3 | -0.0209241 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0209207 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0209043 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0208547 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.02072 |
| PGK1 | phosphoglycerate kinase 1 | -0.0206969 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0205682 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0205631 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0204095 |
| TXNIP | thioredoxin interacting protein | -0.0201743 |
| RBM25 | RNA binding motif protein 25 | -0.0201603 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0200803 |
| RPS13 | ribosomal protein S13 | -0.0198623 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0196125 |
| QKI | QKI, KH domain containing, RNA binding | -0.0195277 |
| RPLP2 | ribosomal protein, large, P2 | -0.0192075 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.019139 |
| NF1 | neurofibromin 1 | -0.0186346 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0186272 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0185973 |
| RPS24 | ribosomal protein S24 | -0.0185617 |
| RPL31 | ribosomal protein L31 | -0.0184929 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0183526 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0179447 |
| RRBP1 | ribosome binding protein 1 | -0.0177412 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0173241 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0171679 |
| RPS12 | ribosomal protein S12 | -0.0169523 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0169063 |
| RPS21 | ribosomal protein S21 | -0.0168386 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0166505 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0166049 |
| TMEM263 | transmembrane protein 263 | -0.0165609 |
| FTL | ferritin, light polypeptide | -0.0163874 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0163745 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0161553 |
| RPS25 | ribosomal protein S25 | -0.016032 |
| RPS27A | ribosomal protein S27a | -0.0157987 |
| EVI5 | ecotropic viral integration site 5 | -0.0156999 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0156725 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0154566 |
| RPL27A | ribosomal protein L27a | -0.015446 |
| COG5 | component of oligomeric golgi complex 5 | -0.0154396 |
